Lineage for Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2426096Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2426097Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2428331Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 protein domains)
    family members also share a common alpha+beta fold in C-terminal domain

Protein Domains:

  1. 24283321-deoxy-D-xylulose-5-phosphate reductoisomerase [69410] (2 species)
    1. 2428333Species Escherichia coli [TaxId:562] [69411] (11 PDB entries)
      Uniprot P45568
    2. 2428359Species Zymomonas mobilis [TaxId:542] [110420] (2 PDB entries)
      Uniprot Q9X5F2
  2. 2428368Acetaldehyde dehydrogenase (acylating) [89527] (1 species)
  3. 2428374Aspartate beta-semialdehyde dehydrogenase [51813] (4 species)
    1. 2428375Species Escherichia coli [TaxId:562] [51814] (4 PDB entries)
      Uniprot P00353
    2. 2428386Species Haemophilus influenzae [TaxId:727] [102159] (12 PDB entries)
      Uniprot P44801
    3. 2428405Species Pneumococcus (Streptococcus pneumoniae) [TaxId:1313] [141917] (18 PDB entries)
      Uniprot Q8DQ00 2-127,330-357
    4. 2428450Species Vibrio cholerae [TaxId:666] [82297] (4 PDB entries)
  4. 2428458Biliverdin reductase [51823] (1 species)
  5. 2428463Diaminopimelic acid dehydrogenase (DAPDH) [51819] (1 species)
  6. 2428472Dihydrodipicolinate reductase [51821] (3 species)
    1. 2428473Species Escherichia coli [TaxId:562] [51822] (5 PDB entries)
    2. 2428482Species Mycobacterium tuberculosis [TaxId:1773] [102160] (5 PDB entries)
    3. 2428499Species Thermotoga maritima [TaxId:2336] [110417] (1 PDB entry)
      Uniprot Q9X1K8
  7. 2428504Galactose/lactose metabolism regulatory protein GAL80 [141921] (1 species)
  8. 2428515Glucose 6-phosphate dehydrogenase, N-terminal domain [51827] (2 species)
    1. 2428516Species Human (Homo sapiens) [TaxId:9606] [51829] (1 PDB entry)
    2. 2428525Species Leuconostoc mesenteroides [TaxId:1245] [51828] (9 PDB entries)
  9. 2428536Glucose-fructose oxidoreductase, N-terminal domain [51825] (1 species)
  10. 2428572Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) [51801] (20 species)
    1. 2428573Species Achromobacter xylosoxidans [TaxId:85698] [89526] (1 PDB entry)
      formerly Alcaligenes xylosoxidans
    2. 2428576Species American lobster (Homarus americanus) [TaxId:6706] [51810] (2 PDB entries)
    3. 2428583Species Bacillus stearothermophilus, nca 1503 [TaxId:1422] [51803] (11 PDB entries)
    4. 2428628Species Escherichia coli [TaxId:562] [51802] (9 PDB entries)
      Uniprot P06977
    5. 2428648Species Escherichia coli [TaxId:83334] [336836] (1 PDB entry)
    6. 2428650Species Human (Homo sapiens) [TaxId:9606] [51812] (1 PDB entry)
    7. 2428653Species Human (Homo sapiens), liver isoform [TaxId:9606] [141915] (2 PDB entries)
      Uniprot P04406 2-150,315-334
    8. 2428662Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141916] (4 PDB entries)
      Uniprot Q8IKK7 4-152,319-335! Uniprot Q8T6B1 1-152,319-337
    9. 2428679Species Methanothermus fervidus [TaxId:2180] [51807] (1 PDB entry)
    10. 2428684Species Pyrococcus horikoshii [TaxId:53953] [159423] (1 PDB entry)
      Uniprot O59494 1-139,302-334
    11. 2428689Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [102158] (1 PDB entry)
    12. 2428694Species South China Sea lobster (Palinurus versicolor) [TaxId:150436] [51811] (5 PDB entries)
    13. 2428709Species Spinach (Spinacia oleracea) [TaxId:3562] [69409] (8 PDB entries)
      Uniprot P19866
    14. 2428744Species Sulfolobus solfataricus [TaxId:2287] [51806] (1 PDB entry)
    15. 2428747Species Thermotoga maritima [TaxId:2336] [51805] (1 PDB entry)
    16. 2428750Species Thermus aquaticus [TaxId:271] [51804] (2 PDB entries)
    17. 2428767Species Thermus thermophilus [TaxId:274] [102157] (1 PDB entry)
    18. 2428769Species Trypanosoma brucei brucei, glycosome [TaxId:5702] [51808] (1 PDB entry)
    19. 2428776Species Trypanosoma cruzi [TaxId:5693] [75104] (5 PDB entries)
    20. 2428797Species Trypanosome (Leishmania mexicana) [TaxId:5665] [51809] (5 PDB entries)
  11. 2428822Homoserine dehydrogenase [51815] (1 species)
  12. 2428834Hypothetical protein TM0312 [141925] (1 species)
  13. 2428838Hypothetical protein TM1419 [102161] (1 species)
    myo-inositol 1-phosphate synthase-related protein
  14. 2428842Hypothetical protein TM1643 [75108] (1 species)
  15. 2428846Myo-inositol 1-phosphate synthase [75105] (4 species)
    1. 2428847Species Archaeoglobus fulgidus [TaxId:2234] [110418] (3 PDB entries)
      Uniprot O28480
    2. 2428854Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [75107] (9 PDB entries)
      Uniprot P11986
    3. 2428877Species Mycobacterium tuberculosis [TaxId:1773] [75106] (1 PDB entry)
    4. 2428879Species Nematode (Caenorhabditis elegans) [TaxId:6239] [110419] (1 PDB entry)
      Uniprot Q18664
  16. 2428881N-acetyl-gamma-glutamyl-phosphate reductase ArgC [110423] (3 species)
    1. 2428882Species Salmonella typhimurium [TaxId:90371] [141918] (1 PDB entry)
      Uniprot Q8ZKL8 1-153,309-334
    2. 2428884Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [117428] (2 PDB entries)
      Uniprot O82187 15-359
    3. 2428893Species Thermotoga maritima [TaxId:2336] [110424] (1 PDB entry)
      Uniprot Q9X2A2
  17. 2428898Probable oxidoreductase At4g09670 [117429] (1 species)
  18. 2428904Putative oxidoreductase VCA1048 [110425] (1 species)
  19. 2428910Putative semialdehyde dehydrogenase [141919] (1 species)
  20. 2428916Saccharopine reductase [51817] (1 species)
  21. 2428929Usg-1 protein homolog PA3116 [141923] (1 species)
  22. 2428932Virulence factor MviM [110421] (1 species)

More info for Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Timeline for Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain: