Lineage for d1tb4a1 (1tb4 A:1-133,A:358-368)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2843543Family c.2.1.3: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain [51800] (22 proteins)
    family members also share a common alpha+beta fold in C-terminal domain
  6. 2843586Protein Aspartate beta-semialdehyde dehydrogenase [51813] (4 species)
  7. 2843598Species Haemophilus influenzae [TaxId:727] [102159] (12 PDB entries)
    Uniprot P44801
  8. 2843616Domain d1tb4a1: 1tb4 A:1-133,A:358-368 [112380]
    Other proteins in same PDB: d1tb4a2
    complexed with pej

Details for d1tb4a1

PDB Entry: 1tb4 (more details), 2.15 Å

PDB Description: crystal structure of aspartate-semialdehyde dehydrogenase from haemophilus influenzae with a bound periodate
PDB Compounds: (A:) aspartate-semialdehyde dehydrogenase

SCOPe Domain Sequences for d1tb4a1:

Sequence, based on SEQRES records: (download)

>d1tb4a1 c.2.1.3 (A:1-133,A:358-368) Aspartate beta-semialdehyde dehydrogenase {Haemophilus influenzae [TaxId: 727]}
mknvgfigwrgmvgsvlmdrmsqendfenlnpvffttsqagqkapvfggkdagdlksafd
ieelkkldiivtcqggdytnevypklkatgwdgywvdaasalrmkddaiivldpvnqhvi
seglkkgiktfvggXpvrrilkqlva

Sequence, based on observed residues (ATOM records): (download)

>d1tb4a1 c.2.1.3 (A:1-133,A:358-368) Aspartate beta-semialdehyde dehydrogenase {Haemophilus influenzae [TaxId: 727]}
mknvgfigwrgmvgsvlmdrmsqendfenlnpvffttsqalksafdieelkkldiivtcq
ggdytnevypklkatgwdgywvdaasalrmkddaiivldpvnqhviseglkkgiktfvgg
Xpvrrilkqlva

SCOPe Domain Coordinates for d1tb4a1:

Click to download the PDB-style file with coordinates for d1tb4a1.
(The format of our PDB-style files is described here.)

Timeline for d1tb4a1:

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Domains from same chain:
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d1tb4a2