Lineage for Protein: Interleukin-6

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991438Family a.26.1.1: Long-chain cytokines [47267] (10 protein domains)
  6. 1991478Protein Interleukin-6 [47272] (2 species)

Species:

  1. 1991479Human (Homo sapiens) [TaxId:9606] [47273] (9 PDB entries)
    1. Domain for 1alu:
    2. Domain for 1il6:
    3. Domain for 1p9m:
    4. Domain for 2il6:
    5. Domains for 4cni:
      1. 1991481Domain d4cnic_: 4cni C: [256633]
        Other proteins in same PDB: d4cnib1, d4cnib2, d4cnil1, d4cnil2
        automated match to d4ni9a_
        complexed with so4, tam
      2. 1991482Domain d4cnid_: 4cni D: [256634]
        Other proteins in same PDB: d4cnib1, d4cnib2, d4cnil1, d4cnil2
        automated match to d4ni9a_
        complexed with so4, tam
    6. Domain for 4ni7:
    7. Domains for 4ni9:
      1. 1991483Domain d4ni9a_: 4ni9 A: [236232]
        automated match to d1alua_
        protein/DNA complex; complexed with na
      2. 1991484Domain d4ni9c_: 4ni9 C: [236233]
        automated match to d1alua_
        protein/DNA complex; complexed with na
    8. Domain for 4o9h:
    9. Domain for 4zs7:
  2. 1991490Human herpesvirus 8, Kaposi's sarcoma herpes-virus [TaxId:37296] [63528] (1 PDB entry)

More info for Protein Interleukin-6 from a.26.1.1: Long-chain cytokines

Timeline for Protein Interleukin-6 from a.26.1.1: Long-chain cytokines: