Lineage for d4ni7a_ (4ni7 A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991438Family a.26.1.1: Long-chain cytokines [47267] (10 protein domains)
  6. 1991478Protein Interleukin-6 [47272] (2 species)
  7. 1991479Species Human (Homo sapiens) [TaxId:9606] [47273] (9 PDB entries)
  8. 1991485Domain d4ni7a_: 4ni7 A: [236231]
    automated match to d1alua_
    protein/DNA complex; complexed with na

Details for d4ni7a_

PDB Entry: 4ni7 (more details), 2.4 Å

PDB Description: crystal structure of human interleukin 6 in complex with a modified nucleotide aptamer (somamer sl1025)
PDB Compounds: (A:) interleukin-6

SCOPe Domain Sequences for d4ni7a_:

Sequence, based on SEQRES records: (download)

>d4ni7a_ a.26.1.1 (A:) Interleukin-6 {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d4ni7a_ a.26.1.1 (A:) Interleukin-6 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4ni7a_:

Click to download the PDB-style file with coordinates for d4ni7a_.
(The format of our PDB-style files is described here.)

Timeline for d4ni7a_: