Lineage for Species: Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2091104Protein Enoyl-ACP reductase [51791] (11 species)
  7. 2091223Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] [51793] (70 PDB entries)

PDB entries in Species: Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]:

  1. Domain(s) for 1bvr:
    1. 2091348Domain d1bvra_: 1bvr A: [29913]
      complexed with nad, tht
    2. 2091349Domain d1bvrb_: 1bvr B: [29914]
      complexed with nad, tht
    3. 2091350Domain d1bvrc_: 1bvr C: [29915]
      complexed with nad, tht
    4. 2091351Domain d1bvrd_: 1bvr D: [29916]
      complexed with nad, tht
    5. 2091352Domain d1bvre_: 1bvr E: [29917]
      complexed with nad, tht
    6. 2091353Domain d1bvrf_: 1bvr F: [29918]
      complexed with nad, tht
  2. Domain(s) for 1eny:
  3. Domain(s) for 1enz:
  4. Domain(s) for 1p44:
    1. 2091331Domain d1p44a_: 1p44 A: [94076]
      complexed with geq, nad
    2. 2091332Domain d1p44b_: 1p44 B: [94077]
      complexed with geq, nad
    3. 2091333Domain d1p44c_: 1p44 C: [94078]
      complexed with geq, nad
    4. 2091334Domain d1p44d_: 1p44 D: [94079]
      complexed with geq, nad
    5. 2091335Domain d1p44e_: 1p44 E: [94080]
      complexed with geq, nad
    6. 2091336Domain d1p44f_: 1p44 F: [94081]
      complexed with geq, nad
  5. Domain(s) for 1p45:
    1. 2091346Domain d1p45a_: 1p45 A: [94082]
      complexed with nad, tcl
    2. 2091347Domain d1p45b_: 1p45 B: [94083]
      complexed with nad, tcl
  6. Domain(s) for 1zid:
  7. Domain(s) for 2aq8:
  8. Domain(s) for 2aqh:
  9. Domain(s) for 2aqi:
  10. Domain(s) for 2aqk:
  11. Domain(s) for 2b35:
    1. 2091314Domain d2b35a_: 2b35 A: [127767]
      automated match to d1bvra_
      complexed with nad, tcl
    2. 2091315Domain d2b35b_: 2b35 B: [127768]
      automated match to d1bvra_
      complexed with nad, tcl
    3. 2091316Domain d2b35c_: 2b35 C: [127769]
      automated match to d1bvra_
      complexed with nad, tcl
    4. 2091317Domain d2b35d_: 2b35 D: [127770]
      automated match to d1bvra_
      complexed with nad, tcl
    5. 2091318Domain d2b35e_: 2b35 E: [127771]
      automated match to d1bvra_
      complexed with nad, tcl
    6. 2091319Domain d2b35f_: 2b35 F: [127772]
      automated match to d1bvra_
      complexed with nad, tcl
  12. Domain(s) for 2b36:
    1. 2091354Domain d2b36a_: 2b36 A: [127773]
      automated match to d1bvra_
      complexed with 5pp, nad
    2. 2091355Domain d2b36b_: 2b36 B: [127774]
      automated match to d1bvra_
      complexed with 5pp, nad
    3. 2091356Domain d2b36c_: 2b36 C: [127775]
      automated match to d1bvra_
      complexed with 5pp, nad
    4. 2091357Domain d2b36d_: 2b36 D: [127776]
      automated match to d1bvra_
      complexed with 5pp, nad
    5. 2091358Domain d2b36e_: 2b36 E: [127777]
      automated match to d1bvra_
      complexed with 5pp, nad
    6. 2091359Domain d2b36f_: 2b36 F: [127778]
      automated match to d1bvra_
      complexed with 5pp, nad
  13. Domain(s) for 2b37:
    1. 2091325Domain d2b37a_: 2b37 A: [127779]
      automated match to d1bvra_
      complexed with 8ps, nad
    2. 2091326Domain d2b37b_: 2b37 B: [127780]
      automated match to d1bvra_
      complexed with 8ps, nad
    3. 2091327Domain d2b37c_: 2b37 C: [127781]
      automated match to d1bvra_
      complexed with 8ps, nad
    4. 2091328Domain d2b37d_: 2b37 D: [127782]
      automated match to d1bvra_
      complexed with 8ps, nad
    5. 2091329Domain d2b37e_: 2b37 E: [127783]
      automated match to d1bvra_
      complexed with 8ps, nad
    6. 2091330Domain d2b37f_: 2b37 F: [127784]
      automated match to d1bvra_
      complexed with 8ps, nad
  14. Domain(s) for 2h7i:
  15. Domain(s) for 2h7l:
  16. Domain(s) for 2h7m:
  17. Domain(s) for 2h7n:
  18. Domain(s) for 2h7p:
  19. Domain(s) for 2h9i:
  20. Domain(s) for 2idz:
  21. Domain(s) for 2ie0:
  22. Domain(s) for 2ieb:
  23. Domain(s) for 2ied:
    1. 2091257Domain d2ieda_: 2ied A: [147643]
      automated match to d1bvra_
      mutant
    2. 2091258Domain d2iedb_: 2ied B: [147644]
      automated match to d1bvra_
      mutant
    3. 2091259Domain d2iedc_: 2ied C: [147645]
      automated match to d1bvra_
      mutant
    4. 2091260Domain d2iedd_: 2ied D: [147646]
      automated match to d1bvra_
      mutant
  24. Domain(s) for 2nsd:
    1. 2091255Domain d2nsda_: 2nsd A: [148384]
      automated match to d1bvra_
      complexed with 4pi, nad
    2. 2091256Domain d2nsdb_: 2nsd B: [148385]
      automated match to d1bvra_
      complexed with 4pi, nad
  25. Domain(s) for 2ntj:
    1. 2091312Domain d2ntja_: 2ntj A: [138581]
      automated match to d1eny__
      complexed with p1h
    2. 2091313Domain d2ntjb_: 2ntj B: [138582]
      automated match to d1eny__
      complexed with p1h
  26. Domain(s) for 2nv6:
  27. Domain(s) for 2pr2:
  28. Domain(s) for 2x22:
    1. 2091247Domain d2x22a_: 2x22 A: [169811]
      automated match to d1bvra_
      complexed with dms, nad, tcu
    2. 2091248Domain d2x22b_: 2x22 B: [169812]
      automated match to d1bvra_
      complexed with dms, nad, tcu
  29. Domain(s) for 2x23:
    1. 2091227Domain d2x23a_: 2x23 A: [169813]
      automated match to d1bvra_
      complexed with dms, nad, tcu
    2. 2091228Domain d2x23b_: 2x23 B: [169814]
      automated match to d1bvra_
      complexed with dms, nad, tcu
    3. 2091229Domain d2x23e_: 2x23 E: [169815]
      automated match to d1bvra_
      complexed with dms, nad, tcu
    4. 2091230Domain d2x23g_: 2x23 G: [169816]
      automated match to d1bvra_
      complexed with dms, nad, tcu
  30. Domain(s) for 3fne:
    1. 2091249Domain d3fnea_: 3fne A: [175911]
      automated match to d1bvra_
      complexed with 8pc, nad
    2. 2091250Domain d3fneb_: 3fne B: [175912]
      automated match to d1bvra_
      complexed with 8pc, nad
    3. 2091251Domain d3fnec_: 3fne C: [175913]
      automated match to d1bvra_
      complexed with 8pc, nad
    4. 2091252Domain d3fned_: 3fne D: [175914]
      automated match to d1bvra_
      complexed with 8pc, nad
  31. Domain(s) for 3fnf:
    1. 2091296Domain d3fnfa_: 3fnf A: [175915]
      automated match to d1bvra_
      complexed with jpm, nad
    2. 2091297Domain d3fnfb_: 3fnf B: [175916]
      automated match to d1bvra_
      complexed with jpm, nad
    3. 2091298Domain d3fnfc_: 3fnf C: [175917]
      automated match to d1bvra_
      complexed with jpm, nad
    4. 2091299Domain d3fnfd_: 3fnf D: [175918]
      automated match to d1bvra_
      complexed with jpm, nad
  32. Domain(s) for 3fng:
  33. Domain(s) for 3fnh:
  34. Domain(s) for 3oew:
  35. Domain(s) for 3oey:
  36. Domain(s) for 3of2:
  37. Domain(s) for 4bge:
    1. 2091337Domain d4bgea_: 4bge A: [229364]
      automated match to d2aqka_
      complexed with pyw; mutant
    2. 2091338Domain d4bgeb_: 4bge B: [229368]
      automated match to d2aqka_
      complexed with pyw; mutant
    3. 2091339Domain d4bgec_: 4bge C: [229367]
      automated match to d2aqka_
      complexed with pyw; mutant
    4. 2091340Domain d4bged_: 4bge D: [229363]
      automated match to d2aqka_
      complexed with pyw; mutant
    5. 2091341Domain d4bgee_: 4bge E: [229362]
      automated match to d2aqka_
      complexed with pyw; mutant
    6. 2091342Domain d4bgef_: 4bge F: [229370]
      automated match to d2aqka_
      complexed with pyw; mutant
  38. Domain(s) for 4bii:
    1. 2091261Domain d4biia_: 4bii A: [229371]
      automated match to d1p44a_
      complexed with nad, pyw
    2. 2091262Domain d4biib_: 4bii B: [229365]
      automated match to d1p44a_
      complexed with nad, pyw
    3. 2091263Domain d4biic_: 4bii C: [229369]
      automated match to d1p44a_
      complexed with nad, pyw
    4. 2091264Domain d4biid_: 4bii D: [229366]
      automated match to d1p44a_
      complexed with nad, pyw
  39. Domain(s) for 4bqp:
    1. 2091273Domain d4bqpa_: 4bqp A: [229515]
      automated match to d1p44a_
      complexed with na, nad, vmy
    2. 2091274Domain d4bqpb_: 4bqp B: [229512]
      automated match to d1p44a_
      complexed with na, nad, vmy
    3. 2091275Domain d4bqpc_: 4bqp C: [229509]
      automated match to d1p44a_
      complexed with na, nad, vmy
    4. 2091276Domain d4bqpd_: 4bqp D: [229513]
      automated match to d1p44a_
      complexed with na, nad, vmy
    5. 2091277Domain d4bqpe_: 4bqp E: [229514]
      automated match to d1p44a_
      complexed with na, nad, vmy
    6. 2091278Domain d4bqpf_: 4bqp F: [229511]
      automated match to d1p44a_
      complexed with na, nad, vmy
  40. Domain(s) for 4bqr:
    1. 2091287Domain d4bqra_: 4bqr A: [229510]
      automated match to d1p44a_
      complexed with ibh, nad
    2. 2091288Domain d4bqrb_: 4bqr B: [229507]
      automated match to d1p44a_
      complexed with ibh, nad
    3. 2091289Domain d4bqrc_: 4bqr C: [229508]
      automated match to d1p44a_
      complexed with ibh, nad
    4. 2091290Domain d4bqrd_: 4bqr D: [229516]
      automated match to d1p44a_
      complexed with ibh, nad
  41. Domain(s) for 4cod:
    1. 2091308Domain d4codb_: 4cod B: [236702]
      automated match to d1p44a_
      complexed with kv1, nad
    2. 2091309Domain d4codd_: 4cod D: [236704]
      automated match to d1p44a_
      complexed with kv1, nad
    3. 2091310Domain d4codf_: 4cod F: [236703]
      automated match to d1p44a_
      complexed with kv1, nad
    4. 2091311Domain d4codh_: 4cod H: [236705]
      automated match to d1p44a_
      complexed with kv1, nad
  42. Domain(s) for 4d0r:
  43. Domain(s) for 4d0s:
    1. 2091242Domain d4d0sa_: 4d0s A: [272854]
      automated match to d1p44a_
      complexed with 9g4, mg, nad
    2. 2091243Domain d4d0sb_: 4d0s B: [272850]
      automated match to d1p44a_
      complexed with 9g4, mg, nad
    3. 2091244Domain d4d0sc_: 4d0s C: [272853]
      automated match to d1p44a_
      complexed with 9g4, mg, nad
    4. 2091245Domain d4d0sd_: 4d0s D: [272849]
      automated match to d1p44a_
      complexed with 9g4, mg, nad
  44. Domain(s) for 4dqu:
  45. Domain(s) for 4dre:
  46. Domain(s) for 4dti:
  47. Domain(s) for 4oim:
  48. Domain(s) for 4qxm:
    1. 2091321Domain d4qxma_: 4qxm A: [275213]
      automated match to d1p44a_
      complexed with 713, nad
    2. 2091322Domain d4qxmc_: 4qxm C: [275214]
      automated match to d1p44a_
      complexed with 713, nad
    3. 2091323Domain d4qxme_: 4qxm E: [275216]
      automated match to d1p44a_
      complexed with 713, nad
    4. 2091324Domain d4qxmg_: 4qxm G: [275217]
      automated match to d1p44a_
      complexed with 713, nad
  49. Domain(s) for 4r9r:
    1. 2091363Domain d4r9ra_: 4r9r A: [268685]
      automated match to d4tzka_
      complexed with 3kx, nad
    2. 2091364Domain d4r9rc_: 4r9r C: [268686]
      automated match to d4tzka_
      complexed with 3kx, nad
    3. 2091365Domain d4r9re_: 4r9r E: [268683]
      automated match to d4tzka_
      complexed with 3kx, nad
    4. 2091366Domain d4r9rg_: 4r9r G: [268684]
      automated match to d4tzka_
      complexed with 3kx, nad
  50. Domain(s) for 4trj:
  51. Domain(s) for 4trm:
    1. 2091279Domain d4trma_: 4trm A: [271980]
      automated match to d1p44a_
      complexed with mes
    2. 2091280Domain d4trmb_: 4trm B: [271979]
      automated match to d1p44a_
      complexed with mes
    3. 2091281Domain d4trmc_: 4trm C: [271970]
      automated match to d1p44a_
      complexed with mes
    4. 2091282Domain d4trmd_: 4trm D: [271972]
      automated match to d1p44a_
      complexed with mes
    5. 2091283Domain d4trme_: 4trm E: [271969]
      automated match to d1p44a_
      complexed with mes
    6. 2091284Domain d4trmf_: 4trm F: [271968]
      automated match to d1p44a_
      complexed with mes
  52. Domain(s) for 4trn:
  53. Domain(s) for 4tro:
  54. Domain(s) for 4tzk:
  55. Domain(s) for 4tzt:
  56. Domain(s) for 4u0j:
  57. Domain(s) for 4u0k:
  58. Domain(s) for 4uvd:
  59. Domain(s) for 4uve:
  60. Domain(s) for 4uvg:
  61. Domain(s) for 4uvh:
    1. 2091292Domain d4uvha_: 4uvh A: [277589]
      automated match to d1p44a_
      complexed with act, nad, uud
    2. 2091293Domain d4uvhb_: 4uvh B: [277585]
      automated match to d1p44a_
      complexed with act, nad, uud
    3. 2091294Domain d4uvhc_: 4uvh C: [277591]
      automated match to d1p44a_
      complexed with act, nad, uud
    4. 2091295Domain d4uvhd_: 4uvh D: [277590]
      automated match to d1p44a_
      complexed with act, nad, uud
  62. Domain(s) for 4uvi:
    1. 2091265Domain d4uvia_: 4uvi A: [277584]
      automated match to d1p44a_
      complexed with kxu, nad
    2. 2091266Domain d4uvib_: 4uvi B: [277583]
      automated match to d1p44a_
      complexed with kxu, nad
    3. 2091267Domain d4uvic_: 4uvi C: [277588]
      automated match to d1p44a_
      complexed with kxu, nad
    4. 2091268Domain d4uvid_: 4uvi D: [277586]
      automated match to d1p44a_
      complexed with kxu, nad
  63. Domain(s) for 5cp8:
  64. Domain(s) for 5g0s:
    1. 2283329Domain d5g0sc_: 5g0s C: [326630]
      automated match to d1p44a_
      protein/DNA complex; complexed with eeh, nad
    2. 2283352Domain d5g0sa_: 5g0s A: [326653]
      automated match to d1p44a_
      protein/DNA complex; complexed with eeh, nad
    3. 2283393Domain d5g0sd_: 5g0s D: [326694]
      automated match to d1p44a_
      protein/DNA complex; complexed with eeh, nad
    4. 2283443Domain d5g0sb_: 5g0s B: [326744]
      automated match to d1p44a_
      protein/DNA complex; complexed with eeh, nad
  65. Domain(s) for 5g0t:
    1. 2283333Domain d5g0td_: 5g0t D: [326634]
      automated match to d1p44a_
      protein/DNA complex; complexed with nad, s72
    2. 2283389Domain d5g0tb_: 5g0t B: [326690]
      automated match to d1p44a_
      protein/DNA complex; complexed with nad, s72
    3. 2283419Domain d5g0tc_: 5g0t C: [326720]
      automated match to d1p44a_
      protein/DNA complex; complexed with nad, s72
    4. 2283454Domain d5g0ta_: 5g0t A: [326755]
      automated match to d1p44a_
      protein/DNA complex; complexed with nad, s72
  66. Domain(s) for 5g0u:
    1. 2283325Domain d5g0ud_: 5g0u D: [326626]
      automated match to d1p44a_
      protein/DNA complex; complexed with 9cv, nad
    2. 2283326Domain d5g0uc_: 5g0u C: [326627]
      automated match to d1p44a_
      protein/DNA complex; complexed with 9cv, nad
    3. 2283360Domain d5g0ua_: 5g0u A: [326661]
      automated match to d1p44a_
      protein/DNA complex; complexed with 9cv, nad
    4. 2283442Domain d5g0ub_: 5g0u B: [326743]
      automated match to d1p44a_
      protein/DNA complex; complexed with 9cv, nad
  67. Domain(s) for 5g0v:
    1. 2283327Domain d5g0va_: 5g0v A: [326628]
      automated match to d1p44a_
      protein/DNA complex; complexed with jdd, mg, nad
    2. 2283328Domain d5g0vc_: 5g0v C: [326629]
      automated match to d1p44a_
      protein/DNA complex; complexed with jdd, mg, nad
    3. 2283392Domain d5g0vb_: 5g0v B: [326693]
      automated match to d1p44a_
      protein/DNA complex; complexed with jdd, mg, nad
    4. 2283438Domain d5g0vd_: 5g0v D: [326739]
      automated match to d1p44a_
      protein/DNA complex; complexed with jdd, mg, nad
  68. Domain(s) for 5g0w:
    1. 2283323Domain d5g0wc_: 5g0w C: [326624]
      automated match to d1p44a_
      protein/DNA complex; complexed with 9nu, mg, nad
    2. 2283350Domain d5g0wb_: 5g0w B: [326651]
      automated match to d1p44a_
      protein/DNA complex; complexed with 9nu, mg, nad
    3. 2283390Domain d5g0wd_: 5g0w D: [326691]
      automated match to d1p44a_
      protein/DNA complex; complexed with 9nu, mg, nad
    4. 2283403Domain d5g0wa_: 5g0w A: [326704]
      automated match to d1p44a_
      protein/DNA complex; complexed with 9nu, mg, nad
  69. Domain(s) for 5jfo:
    1. 2277744Domain d5jfod_: 5jfo D: [321045]
      automated match to d1p44a_
      complexed with 6ka, nad
    2. 2277769Domain d5jfoc_: 5jfo C: [321070]
      automated match to d1p44a_
      complexed with 6ka, nad
    3. 2277832Domain d5jfob_: 5jfo B: [321133]
      automated match to d1p44a_
      complexed with 6ka, nad
    4. 2277871Domain d5jfoa_: 5jfo A: [321172]
      automated match to d1p44a_
      complexed with 6ka, nad
  70. Domain(s) for 5ugu:

More info for Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase

Timeline for Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] from c.2.1.2 Enoyl-ACP reductase: