PDB entry 6yuu

View 6yuu on RCSB PDB site
Description: Crystal structure of M. tuberculosis InhA inhibited by SKTS1
Class: oxidoreductase
Keywords: bacterial enoyl-ACP reductase, diphenylether, residence time, oxidoreductase
Deposited on 2020-04-27, released 2021-03-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-21, with a file datestamp of 2021-04-16.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Mycobacterium tuberculosis CDC1551 [TaxId:83331]
    Gene: inhA, MT1531
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6yuua_
  • Heterogens: F9T, NAD, CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6yuuA (A:)
mgsshhhhhhssglvprgshmtglldgkrilvsgiitdssiafhiarvaqeqgaqlvltg
fdrlrliqritdrlpakaplleldvqneehlaslagrvteaigagnkldgvvhsigfmpq
tgmginpffdapyadvskgihisaysyasmakallpimnpggsivgmdfdpsrampaynw
mtvaksalesvnrfvareagkygvrsnlvaagpirtlamsaivggalgeeagaqiqllee
gwdqrapigwnmkdatpvaktvcallsdwlpattgdiiyadggahtqll

    Sequence, based on observed residues (ATOM records): (download) 
    >6yuuA (A:)
tglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakapll
eldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgih
isaysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareagk
ygvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvakt
vcallsdwlpattgdiiyadggahtqll