Lineage for d4u0ja_ (4u0j A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2426096Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2426097Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2426443Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2427028Protein Enoyl-ACP reductase [51791] (11 species)
  7. 2427148Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] [51793] (86 PDB entries)
  8. 2427164Domain d4u0ja_: 4u0j A: [258542]
    automated match to d1p44a_
    complexed with 566, nad

Details for d4u0ja_

PDB Entry: 4u0j (more details), 1.62 Å

PDB Description: crystal structure of mycobacterium tuberculosis enoyl reductase (inha) complexed with 1-cyclohexyl-5-oxo-n-phenylpyrrolidine-3-carboxamide, refined with new ligand restraints
PDB Compounds: (A:) Enoyl-[acyl-carrier-protein] reductase [NADH]

SCOPe Domain Sequences for d4u0ja_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4u0ja_ c.2.1.2 (A:) Enoyl-ACP reductase {Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]}

SCOPe Domain Coordinates for d4u0ja_:

Click to download the PDB-style file with coordinates for d4u0ja_.
(The format of our PDB-style files is described here.)

Timeline for d4u0ja_: