SCOPe 2.08: Domain d2h9ia2: 2h9i A:3-269

Lineage for d2h9ia2 (2h9i A:3-269)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein Enoyl-ACP reductase [51791] (11 species)

7. Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] [51793] (96 PDB entries)

8. Domain d2h9ia2: 2h9i A:3-269 [136265]
   Other proteins in same PDB: d2h9ia3
   automated match to d1eny__
   complexed with ead

Details for d2h9ia2

PDB Entry: 2h9i, 2.2 Å

PDB Description: mycobacterium tuberculosis inha bound with eth-nad adduct

PDB Compounds: (A:) Enoyl-[acyl-carrier-protein] reductase [NADH]

SCOPe Domain Sequences for d2h9ia2:

Sequence; same for both SEQRES and ATOM records:

>d2h9ia2 c.2.1.2 (A:3-269) Enoyl-ACP reductase {Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]}
glldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakaplle
ldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgihi
saysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareagky
gvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvaktv
callsdwlpattgdiiyadggahtqll

Timeline for d2h9ia2:

• d2h9ia2 first appeared in SCOP 1.73, called d2h9ia1
  
• d2h9ia2 was called d2h9ia_ in SCOPe 2.07