PDB entry 6sq5

View 6sq5 on RCSB PDB site
Description: Crystal structure of M. tuberculosis InhA in complex with NAD+ and 3-[3-(trifluoromethyl)phenyl]prop-2-enoic acid
Class: oxidoreductase
Keywords: InhA, NADH-dependent enoyl-[acyl-carrier-protein] reductase, OXIDOREDUCTASE
Deposited on 2019-09-03, released 2020-04-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: XRAY
Resolution: 1.84 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: inhA, Rv1484, MTCY277.05
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6sq5a_
  • Heterogens: LRW, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6sq5A (A:)
smtglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakap
lleldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskg
ihisaysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvarea
gkygvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpva
ktvcallsdwlpattgdiiyadggahtqll

    Sequence, based on observed residues (ATOM records): (download) 
    >6sq5A (A:)
glldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakaplle
ldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgihi
saysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareagky
gvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvaktv
callsdwlpattgdiiyadggahtqll