Lineage for Protein: Pyruvate oxidase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2107255Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2107256Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2107283Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 protein domains)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
  6. 2107461Protein Pyruvate oxidase [52476] (2 species)
    binds FAD

Species:

  1. 2107462Aerococcus viridans [TaxId:1377] [142122] (2 PDB entries)
    1. Domain for 1v5e:
    2. Domain for 2dji:
  2. 2107465Lactobacillus plantarum [TaxId:1590] [52477] (8 PDB entries)
    1. Domains for 1pow:
      1. 2107482Domain d1powa1: 1pow A:183-365 [31733]
        Other proteins in same PDB: d1powa2, d1powa3, d1powb2, d1powb3
        complexed with fad, mg, tpp; mutant
      2. 2107483Domain d1powb1: 1pow B:183-365 [31734]
        Other proteins in same PDB: d1powa2, d1powa3, d1powb2, d1powb3
        complexed with fad, mg, tpp; mutant
    2. Domains for 1pox:
      1. 2107472Domain d1poxa1: 1pox A:183-365 [31731]
        Other proteins in same PDB: d1poxa2, d1poxa3, d1poxb2, d1poxb3
        complexed with fad, gol, mg, na, tpp; mutant
      2. 2107473Domain d1poxb1: 1pox B:183-365 [31732]
        Other proteins in same PDB: d1poxa2, d1poxa3, d1poxb2, d1poxb3
        complexed with fad, gol, mg, na, tpp; mutant
    3. Domains for 1y9d:
      1. 2107478Domain d1y9da2: 1y9d A:192-365 [240983]
        Other proteins in same PDB: d1y9da1, d1y9da3, d1y9db1, d1y9db3, d1y9dc1, d1y9dc3, d1y9dd1, d1y9dd3
        automated match to d2ez9a1
        complexed with fad, mg, na, so4, tpp
      2. 2107479Domain d1y9db2: 1y9d B:183-365 [240986]
        Other proteins in same PDB: d1y9da1, d1y9da3, d1y9db1, d1y9db3, d1y9dc1, d1y9dc3, d1y9dd1, d1y9dd3
        automated match to d2ez9a1
        complexed with fad, mg, na, so4, tpp
      3. 2107480Domain d1y9dc2: 1y9d C:194-365 [240989]
        Other proteins in same PDB: d1y9da1, d1y9da3, d1y9db1, d1y9db3, d1y9dc1, d1y9dc3, d1y9dd1, d1y9dd3
        automated match to d2ez9a1
        complexed with fad, mg, na, so4, tpp
      4. 2107481Domain d1y9dd2: 1y9d D:183-365 [240992]
        Other proteins in same PDB: d1y9da1, d1y9da3, d1y9db1, d1y9db3, d1y9dc1, d1y9dc3, d1y9dd1, d1y9dd3
        automated match to d2ez9a1
        complexed with fad, mg, na, so4, tpp
    4. Domains for 2ez4:
      1. 2107470Domain d2ez4a1: 2ez4 A:183-365 [132610]
        Other proteins in same PDB: d2ez4a2, d2ez4a3, d2ez4b2, d2ez4b3
        automated match to d2ez9a1
        complexed with fad, mg, na, po4, tpp
      2. 2107471Domain d2ez4b1: 2ez4 B:183-365 [132613]
        Other proteins in same PDB: d2ez4a2, d2ez4a3, d2ez4b2, d2ez4b3
        automated match to d2ez9a1
        complexed with fad, mg, na, po4, tpp
    5. Domains for 2ez8:
      1. 2107468Domain d2ez8a1: 2ez8 A:183-365 [132621]
        Other proteins in same PDB: d2ez8a2, d2ez8a3, d2ez8b2, d2ez8b3
        automated match to d2ez9a1
        complexed with fad, mg, na, pyr, tdl
      2. 2107469Domain d2ez8b1: 2ez8 B:183-365 [132624]
        Other proteins in same PDB: d2ez8a2, d2ez8a3, d2ez8b2, d2ez8b3
        automated match to d2ez9a1
        complexed with fad, mg, na, pyr, tdl
    6. Domains for 2ez9:
      1. 2107466Domain d2ez9a1: 2ez9 A:183-365 [132627]
        Other proteins in same PDB: d2ez9a2, d2ez9a3, d2ez9b2, d2ez9b3
        automated match to d2ez9a1
        complexed with fad, mg, na, tdk
      2. 2107467Domain d2ez9b1: 2ez9 B:183-365 [132630]
        Other proteins in same PDB: d2ez9a2, d2ez9a3, d2ez9b2, d2ez9b3
        automated match to d2ez9b1
        complexed with fad, mg, na, tdk
    7. Domains for 2ezt:
      1. 2107476Domain d2ezta1: 2ezt A:183-365 [132633]
        Other proteins in same PDB: d2ezta2, d2ezta3, d2eztb2, d2eztb3
        automated match to d2ezua1
        complexed with fad, mg, na, po4, pyr, tdm
      2. 2107477Domain d2eztb1: 2ezt B:183-365 [132636]
        Other proteins in same PDB: d2ezta2, d2ezta3, d2eztb2, d2eztb3
        automated match to d2ezua1
        complexed with fad, mg, na, po4, pyr, tdm
    8. Domains for 2ezu:
      1. 2107474Domain d2ezua1: 2ezu A:183-365 [132639]
        Other proteins in same PDB: d2ezua2, d2ezua3, d2ezub2, d2ezub3
        automated match to d2ezua1
        complexed with fad, htl, mg, na, pyr
      2. 2107475Domain d2ezub1: 2ezu B:183-365 [132642]
        Other proteins in same PDB: d2ezua2, d2ezua3, d2ezub2, d2ezub3
        automated match to d2ezua1
        complexed with fad, htl, mg, na, pyr

More info for Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain: