Superfamily c.31.1: DHS-like NAD/FAD-binding domain

Structural Classification of Proteins and ASTRAL release 1.75B (January 2013)

Lineage for Superfamily c.31.1: DHS-like NAD/FAD-binding domain

Root: SCOP 1.75B
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
binds cofactor molecules in the opposite direction than classical Rossmann fold

c.31.1.1: Deoxyhypusine synthase, DHS [52468] (1 protein)
c.31.1.2: C-terminal domain of the electron transfer flavoprotein alpha subunit [52471] (1 protein)
lacks strand 3; shares the FAD-binding mode with the pyruvate oxidase domain
c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 protein domains)
N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
c.31.1.4: Transhydrogenase domain III (dIII) [52484] (1 protein)
binds NADP, shares with the pyruvate oxidase FAD-binding domain a common ADP-binding mode
c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 protein domains)
silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
c.31.1.6: ACDE2-like [142130] (1 protein)
Pfam PF02552
c.31.1.0: automated matches [191352] (1 protein)
not a true family

Timeline for Superfamily c.31.1: DHS-like NAD/FAD-binding domain:

Superfamily c.31.1: DHS-like NAD/FAD-binding domain appears in SCOP 1.75A