SCOPe 2.08: Family c.31.1.1: Deoxyhypusine synthase, DHS

Lineage for Family c.31.1.1: Deoxyhypusine synthase, DHS

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.1: Deoxyhypusine synthase, DHS [52468] (2 proteins)
   automatically mapped to Pfam PF01916

Proteins:

1. Deoxyhypusine synthase, DHS [52469] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [52470] (14 PDB entries)
     Uniprot P49366

2. automated matches [396027] (1 species)
   not a true protein

   • Species Nematode (Brugia malayi) [TaxId:6279] [396028] (1 PDB entry)

More info for Family c.31.1.1: Deoxyhypusine synthase, DHS

Timeline for Family c.31.1.1: Deoxyhypusine synthase, DHS:

• Family c.31.1.1: Deoxyhypusine synthase, DHS first appeared (with stable ids) in SCOP 1.55
  
• Family c.31.1.1: Deoxyhypusine synthase, DHS appears in SCOPe 2.07