Lineage for d2ezua1 (2ezu A:183-365)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2862578Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2862579Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2862632Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 proteins)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
  6. 2862831Protein Pyruvate oxidase [52476] (2 species)
    binds FAD
  7. 2862835Species Lactobacillus plantarum [TaxId:1590] [52477] (8 PDB entries)
  8. 2862850Domain d2ezua1: 2ezu A:183-365 [132639]
    Other proteins in same PDB: d2ezua2, d2ezua3, d2ezub2, d2ezub3
    automated match to d2ezua1
    complexed with fad, htl, mg, na, pyr

Details for d2ezua1

PDB Entry: 2ezu (more details), 2.16 Å

PDB Description: pyruvate oxidase variant f479w in complex with reaction intermediate 2-acetyl-thiamin diphosphate
PDB Compounds: (A:) Pyruvate oxidase

SCOPe Domain Sequences for d2ezua1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ezua1 c.31.1.3 (A:183-365) Pyruvate oxidase {Lactobacillus plantarum [TaxId: 1590]}

SCOPe Domain Coordinates for d2ezua1:

Click to download the PDB-style file with coordinates for d2ezua1.
(The format of our PDB-style files is described here.)

Timeline for d2ezua1: