![]() | Class b: All beta proteins [48724] (176 folds) |
![]() | Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
![]() | Superfamily b.1.1: Immunoglobulin [48726] (5 families) ![]() |
![]() | Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins) |
![]() | Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species) VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species |
![]() | Species Mouse (Mus musculus), cluster 1.2 [TaxId:10090] [88525] (46 PDB entries) |
![]() | Domain d1a3rl1: 1a3r L:1-114 [19780] Other proteins in same PDB: d1a3rh1, d1a3rh2, d1a3rl2 part of Fab 8F5 |
![]() | Domain d1a5fl1: 1a5f L:1-113 [20302] Other proteins in same PDB: d1a5fh1, d1a5fh2, d1a5fl2 part of an anti-E-selectin Fab |
![]() | Domain d1ap2a_: 1ap2 A: [20182] Other proteins in same PDB: d1ap2b_, d1ap2d_ part of P-glycoprotein-specific scFv C219 |
![]() | Domain d1ap2c_: 1ap2 C: [20184] Other proteins in same PDB: d1ap2b_, d1ap2d_ part of P-glycoprotein-specific scFv C219 |
![]() | Domain d1bbdl1: 1bbd L:1-114 [19782] Other proteins in same PDB: d1bbdh1, d1bbdh2, d1bbdl2 part of Fab 8F5 complexed with so4 |
![]() | Domain d1ck0l1: 1ck0 L:1-107 [90424] Other proteins in same PDB: d1ck0h1, d1ck0h2, d1ck0l2 part of anti-anti-idiotypic Fab against human angiotensin II, unliganded form |
![]() | Domain d1frgl1: 1frg L:1-113 [19924] Other proteins in same PDB: d1frgh1, d1frgh2, d1frgl2 part of Fab 26/9 |
![]() | Domain d1h3pl1: 1h3p L:1-107 [76650] Other proteins in same PDB: d1h3ph1, d1h3ph2, d1h3pl2 part of anti-hepatitis B Fab (against PRES1 region) |
![]() | Domain d1himh1: 1him H:1-108 [19793] Other proteins in same PDB: d1himh2, d1himj2, d1himl1, d1himl2, d1himm1, d1himm2 part of Fab 17/9; chain identifiers are mixed up |
![]() | Domain d1himj1: 1him J:1-108 [19795] Other proteins in same PDB: d1himh2, d1himj2, d1himl1, d1himl2, d1himm1, d1himm2 part of Fab 17/9; chain identifiers are mixed up |
![]() | Domain d1hinl1: 1hin L:1-108 [19796] Other proteins in same PDB: d1hinh1, d1hinh2, d1hinl2 part of Fab 17/9 |
![]() | Domain d1ifhl1: 1ifh L:1-108 [19790] Other proteins in same PDB: d1ifhh1, d1ifhh2, d1ifhl2 part of Fab 17/9 |
![]() | Domain d1il1b1: 1il1 B:1-112 [62541] Other proteins in same PDB: d1il1a1, d1il1a2, d1il1b2 part of anti-HIV Fab G3-519 |
![]() | Domain d1mcpl1: 1mcp L:1-114 [19858] Other proteins in same PDB: d1mcph1, d1mcph2, d1mcpl2 part of Fab MCPC603 complexed with so4 |
![]() | Domain d1mhha1: 1mhh A:1-107 [79119] Other proteins in same PDB: d1mhha2, d1mhhb1, d1mhhb2, d1mhhc2, d1mhhd1, d1mhhd2, d1mhhe_, d1mhhf_ part of anti-HCV Fab 19D9D6 complexed with edo |
![]() | Domain d1mhhc1: 1mhh C:1-107 [79123] Other proteins in same PDB: d1mhha2, d1mhhb1, d1mhhb2, d1mhhc2, d1mhhd1, d1mhhd2, d1mhhe_, d1mhhf_ part of anti-HCV Fab 19D9D6 complexed with edo |
![]() | Domain d1mvua_: 1mvu A: [91474] Other proteins in same PDB: d1mvub_ part of P-glycoprotein-specific scFv C219; complexed with synthetic epitope peptide, chain P complexed with so4; mutant |
![]() | Domain d1n64l1: 1n64 L:1-107 [80116] Other proteins in same PDB: d1n64h1, d1n64h2, d1n64l2 part of anti-HCV Fab 19D9D6; complex with peptide, chain P (related to 1cwx) |
![]() | Domain d1nlbl1: 1nlb L:1-107 [80623] Other proteins in same PDB: d1nlbh1, d1nlbh2, d1nlbl2 part of anti-HCV Fab 19D9D6 |
![]() | Domain d1pkqa1: 1pkq A:1-107 [88148] Other proteins in same PDB: d1pkqa2, d1pkqb1, d1pkqb2, d1pkqe_, d1pkqf2, d1pkqg1, d1pkqg2, d1pkqj_ part of humanized Fab 8-18c5 |
![]() | Domain d1pkqf1: 1pkq F:1-107 [88153] Other proteins in same PDB: d1pkqa2, d1pkqb1, d1pkqb2, d1pkqe_, d1pkqf2, d1pkqg1, d1pkqg2, d1pkqj_ part of humanized Fab 8-18c5 |
![]() | Domain d1q9ka1: 1q9k A:1-107 [96276] Other proteins in same PDB: d1q9ka2, d1q9kb1, d1q9kb2 part of Fab s25-2 complexed with mg |
![]() | Domain d1q9la1: 1q9l A:1-107 [96280] Other proteins in same PDB: d1q9la2, d1q9lb1, d1q9lb2, d1q9lc2, d1q9ld1, d1q9ld2 part of Fab s25-2 complexed with mg, zn |
![]() | Domain d1q9lc1: 1q9l C:1-107 [96284] Other proteins in same PDB: d1q9la2, d1q9lb1, d1q9lb2, d1q9lc2, d1q9ld1, d1q9ld2 part of Fab s25-2 complexed with mg, zn |
![]() | Domain d1q9oa1: 1q9o A:1-107 [96292] Other proteins in same PDB: d1q9oa2, d1q9ob1, d1q9ob2, d1q9oc2, d1q9od1, d1q9od2 part of Fab s45-18 complexed with mg |
![]() | Domain d1q9oc1: 1q9o C:1-107 [96296] Other proteins in same PDB: d1q9oa2, d1q9ob1, d1q9ob2, d1q9oc2, d1q9od1, d1q9od2 part of Fab s45-18 complexed with mg |
![]() | Domain d1q9wa1: 1q9w A:1-107 [96320] Other proteins in same PDB: d1q9wa2, d1q9wb1, d1q9wb2, d1q9wc2, d1q9wd1, d1q9wd2 part of Fab s45-18 complexed with mg |
![]() | Domain d1q9wc1: 1q9w C:1-107 [96324] Other proteins in same PDB: d1q9wa2, d1q9wb1, d1q9wb2, d1q9wc2, d1q9wd1, d1q9wd2 part of Fab s45-18 complexed with mg |
![]() | Domain d1sbsl1: 1sbs L:1-113 [20366] Other proteins in same PDB: d1sbsh1, d1sbsh2, d1sbsl2 part of anti-HCG Fab 3A2 complexed with so4 |
![]() | Domain d1t4ka1: 1t4k A:1-107 [112235] Other proteins in same PDB: d1t4ka2, d1t4kb1, d1t4kb2, d1t4kc2, d1t4kd1, d1t4kd2 MQ P01632 P01837 # natural chimera; catalytic antibody with aldolase activity complexed with zn |
![]() | Domain d1t4kc1: 1t4k C:1-107 [112239] Other proteins in same PDB: d1t4ka2, d1t4kb1, d1t4kb2, d1t4kc2, d1t4kd1, d1t4kd2 MQ P01632 P01837 # natural chimera; catalytic antibody with aldolase activity complexed with zn |
![]() | Domain d1ymha1: 1ymh A:1-107 [197663] Other proteins in same PDB: d1ymha2, d1ymhb1, d1ymhb2, d1ymhc2, d1ymhd1, d1ymhd2, d1ymhe_, d1ymhf_ automated match to d1nlbl1 mutant |
![]() | Domain d1ymhc1: 1ymh C:1-107 [197667] Other proteins in same PDB: d1ymha2, d1ymhb1, d1ymhb2, d1ymhc2, d1ymhd1, d1ymhd2, d1ymhe_, d1ymhf_ automated match to d1nlbl1 mutant |
![]() | Domain d2ap2a_: 2ap2 A: [20178] Other proteins in same PDB: d2ap2b_, d2ap2d_ part of P-glycoprotein-specific scFv C219 |
![]() | Domain d2ap2c_: 2ap2 C: [20180] Other proteins in same PDB: d2ap2b_, d2ap2d_ part of P-glycoprotein-specific scFv C219 |
![]() | Domain d2ck0l1: 2ck0 L:1-107 [100855] Other proteins in same PDB: d2ck0h1, d2ck0h2, d2ck0l2 part of anti-anti-idiotypic Fab against human angiotensin II, complex with a synthetic cyclic peptide |
![]() | Domain d2imma_: 2imm A: [19857] VL domain only of MCPC603 complexed with act, so4; mutant |
![]() | Domain d2mcpl1: 2mcp L:1-114 [19860] Other proteins in same PDB: d2mcph1, d2mcph2, d2mcpl2 part of Fab MCPC603 complexed with pc |
![]() | Domain d2r1wa1: 2r1w A:1-107 [205926] Other proteins in same PDB: d2r1wa2, d2r1wb1, d2r1wb2 automated match to d3t65a1 complexed with kda, kdb, mg, zn |
![]() | Domain d2r1xa1: 2r1x A:1-107 [205930] Other proteins in same PDB: d2r1xa2, d2r1xb1, d2r1xb2 automated match to d3t65a1 complexed with kda, kdd, mg, zn |
![]() | Domain d2r1ya1: 2r1y A:1-107 [205934] Other proteins in same PDB: d2r1ya2, d2r1yb1, d2r1yb2 automated match to d3t65a1 complexed with kdo, kdr, mg, zn |
![]() | Domain d2r23a1: 2r23 A:1-107 [205938] Other proteins in same PDB: d2r23a2, d2r23b1, d2r23b2 automated match to d3t65a1 complexed with mg, zn |
![]() | Domain d2r2ba1: 2r2b A:1-107 [205942] Other proteins in same PDB: d2r2ba2, d2r2bb1, d2r2bb2 automated match to d3t65a1 complexed with zn |
![]() | Domain d2r2ea1: 2r2e A:1-107 [205946] Other proteins in same PDB: d2r2ea2, d2r2eb1, d2r2eb2 automated match to d3t65a1 complexed with kde |
![]() | Domain d2r2ha1: 2r2h A:1-107 [205950] Other proteins in same PDB: d2r2ha2, d2r2hb1, d2r2hb2 automated match to d3t65a1 complexed with ko2, mg, zn |
![]() | Domain d3bpca1: 3bpc A:1-107 [208686] Other proteins in same PDB: d3bpca2, d3bpcb1, d3bpcb2 automated match to d3t65a1 complexed with kda, kdb, mg, zn |
![]() | Domain d3ck0l1: 3ck0 L:1-107 [100867] Other proteins in same PDB: d3ck0h1, d3ck0h2, d3ck0l2 part of anti-anti-idiotypic Fab against human angiotensin II, complex with angiotensin II |
![]() | Domain d3sy0a1: 3sy0 A:1-107 [185581] Other proteins in same PDB: d3sy0a2, d3sy0b1, d3sy0b2 part of Fab s25-2 complexed with mg, zn |
![]() | Domain d3t4ya1: 3t4y A:1-107 [185644] Other proteins in same PDB: d3t4ya2, d3t4yb1, d3t4yb2 part of Fab s25-2 complexed with kdo, mg, zn |
![]() | Domain d3t65a1: 3t65 A:1-107 [185654] Other proteins in same PDB: d3t65a2, d3t65b1, d3t65b2 part of Fab s25-2 complexed with mg, zn |
![]() | Domain d3t77a1: 3t77 A:1-107 [185667] Other proteins in same PDB: d3t77a2, d3t77b1, d3t77b2 part of Fab s25-2 complexed with mg, zn |
![]() | Domain d43c9a_: 43c9 A: [20386] Other proteins in same PDB: d43c9b_, d43c9d_, d43c9f_, d43c9h_ part of sterolytic and amidolytic Fv 43c9 |
![]() | Domain d43c9c_: 43c9 C: [20388] Other proteins in same PDB: d43c9b_, d43c9d_, d43c9f_, d43c9h_ part of sterolytic and amidolytic Fv 43c9 |
![]() | Domain d43c9e_: 43c9 E: [20390] Other proteins in same PDB: d43c9b_, d43c9d_, d43c9f_, d43c9h_ part of sterolytic and amidolytic Fv 43c9 |
![]() | Domain d43c9g_: 43c9 G: [20392] Other proteins in same PDB: d43c9b_, d43c9d_, d43c9f_, d43c9h_ part of sterolytic and amidolytic Fv 43c9 |
![]() | Domain d43caa_: 43ca A: [20394] Other proteins in same PDB: d43cab_, d43cad_, d43caf_, d43cah_ part of sterolytic and amidolytic Fv 43c9 complexed with npo |
![]() | Domain d43cac_: 43ca C: [20396] Other proteins in same PDB: d43cab_, d43cad_, d43caf_, d43cah_ part of sterolytic and amidolytic Fv 43c9 complexed with npo |
![]() | Domain d43cae_: 43ca E: [20398] Other proteins in same PDB: d43cab_, d43cad_, d43caf_, d43cah_ part of sterolytic and amidolytic Fv 43c9 complexed with npo |
![]() | Domain d43cag_: 43ca G: [20400] Other proteins in same PDB: d43cab_, d43cad_, d43caf_, d43cah_ part of sterolytic and amidolytic Fv 43c9 complexed with npo |
![]() | Domain d4hgwa1: 4hgw A:1-107 [222598] Other proteins in same PDB: d4hgwa2, d4hgwb1, d4hgwb2 automated match to d3t65a1 complexed with zn |
Timeline for Species Mouse (Mus musculus), cluster 1.2 [TaxId:10090] from b.1.1.1 Immunoglobulin light chain kappa variable domain, VL-kappa: