SCOPe 2.04: Domain d3sy0b1: 3sy0 B:1-111

Lineage for d3sy0b1 (3sy0 B:1-111)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1 [TaxId:10090] [88548] (57 PDB entries)
   Uniprot P01796 # ! HV27_MOUSE Ig heavy chain V-III region A4

8. Domain d3sy0b1: 3sy0 B:1-111 [185583]
   Other proteins in same PDB: d3sy0a1, d3sy0a2, d3sy0b2
   part of Fab s25-2
   complexed with mg, zn

Details for d3sy0b1

PDB Entry: 3sy0, 1.49 Å

PDB Description: s25-2- a(2-8)-a(2-4)kdo trisaccharide complex

PDB Compounds: (B:) S25-2 Fab (IgG1k) heavy chain

SCOPe Domain Sequences for d3sy0b1:

Sequence; same for both SEQRES and ATOM records:

>d3sy0b1 b.1.1.1 (B:1-111) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 1 [TaxId: 10090]}
evklvesggglvqsggslrlscatsgftftdyymswvrqppgkalewlgfirnkangytt
eyspsvkgrftisrdnsqsilylqmntlraedsatyycardhdgyyerfsywgqgtlvtv
sa

Timeline for d3sy0b1:

• d3sy0b1 first appeared in SCOPe 2.01
  
• d3sy0b1 appears in SCOPe 2.03
  
• d3sy0b1 appears in SCOPe 2.05
  
• d3sy0b1 appears in the current release, SCOPe 2.08