SCOPe 2.04: Domain d1ifhl2: 1ifh L:109-212

Lineage for d1ifhl2 (1ifh L:109-212)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (346 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d1ifhl2: 1ifh L:109-212 [20900]
   Other proteins in same PDB: d1ifhh1, d1ifhh2, d1ifhl1
   part of Fab 17/9

Details for d1ifhl2

PDB Entry: 1ifh, 2.8 Å

PDB Description: a detailed analysis of the free and bound conformation of an antibody: x-ray structures of anti-peptide fab 17(slash)9 and three different fab-peptide complexes

PDB Compounds: (L:) igg2a-kappa 17/9 fab (light chain)

SCOPe Domain Sequences for d1ifhl2:

Sequence; same for both SEQRES and ATOM records:

>d1ifhl2 b.1.1.2 (L:109-212) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
adaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqds
kdstysmsstltltkdeyerhnsytceathktstspivksfnrn

Timeline for d1ifhl2:

• d1ifhl2 first appeared (with stable ids) in SCOP 1.55
  
• d1ifhl2 appears in SCOPe 2.03
  
• d1ifhl2 appears in SCOPe 2.05
  
• d1ifhl2 appears in the current release, SCOPe 2.08