SCOPe 2.08: Protein: Syntaxin 1A

Lineage for Protein: Syntaxin 1A

Root: SCOPe 2.08
Class h: Coiled coil proteins [57942] (7 folds)
Fold h.1: Parallel coiled-coil [57943] (41 superfamilies)
this is not a true fold; includes oligomers of shorter identical helices
Superfamily h.1.15: SNARE fusion complex [58038] (2 families)
tetrameric parallel coiled coil
Family h.1.15.1: SNARE fusion complex [58039] (12 proteins)
Protein Syntaxin 1A [88908] (3 species)

Species:

Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [161254] (1 PDB entry)
- Domains for 3b5n:
  1. Domain d3b5nb_: 3b5n B: [154847]
    Other proteins in same PDB: d3b5na2, d3b5na3, d3b5nc2, d3b5nc3, d3b5nc4, d3b5ne_, d3b5ng1, d3b5ng2, d3b5ni_, d3b5nk_
    automated match to d3b5nb1
  2. Domain d3b5nf_: 3b5n F: [154849]
    Other proteins in same PDB: d3b5na2, d3b5na3, d3b5nc2, d3b5nc3, d3b5nc4, d3b5ne_, d3b5ng1, d3b5ng2, d3b5ni_, d3b5nk_
    automated match to d3b5nb1
  3. Domain d3b5nj_: 3b5n J: [154850]
    Other proteins in same PDB: d3b5na2, d3b5na3, d3b5nc2, d3b5nc3, d3b5nc4, d3b5ne_, d3b5ng1, d3b5ng2, d3b5ni_, d3b5nk_
    automated match to d3b5nb_
Longfin inshore squid (Loligo pealei) [TaxId:6621] [88910] (1 PDB entry)
- Domain for 1l4a:
  - Domain d1l4ab1: 1l4a B:183-259 [73560]
    Other proteins in same PDB: d1l4aa_, d1l4ab2, d1l4ac_, d1l4ad_, d1l4ae_
    complex with SNAP25, synaptobrevin and synaphin fragments

Norway rat (Rattus norvegicus) [TaxId:10116] [88909] (6 PDB entries)
Uniprot P32851 196-259
a globular structure of a larger fragment containing this region is available; seepdb:1dn1, chain B

Domains for 1hvv:
1. Domain d1hvva_: 1hvv A: [45639]
  Self-association H3 region of syntaxin 1A
  complexed with tar
2. Domain d1hvvb_: 1hvv B: [45640]
  Self-association H3 region of syntaxin 1A
  complexed with tar
3. Domain d1hvvc_: 1hvv C: [45641]
  Self-association H3 region of syntaxin 1A
  complexed with tar
4. Domain d1hvvd_: 1hvv D: [45642]
  Self-association H3 region of syntaxin 1A
  complexed with tar
Domains for 1jth:
1. Domain d1jthb_: 1jth B: [67271]
  Other proteins in same PDB: d1jtha_, d1jthc_
  complex with SNAP25 fragments
2. Domain d1jthd_: 1jth D: [67273]
  Other proteins in same PDB: d1jtha_, d1jthc_
  complex with SNAP25 fragments
Domain for 1kil:
- Domain d1kilb_: 1kil B: [72519]
  Other proteins in same PDB: d1kila_, d1kilc_, d1kild_, d1kile_
  complex with SNAP25, synaptobrevin and complexin fragments
  complexed with mg
Domain for 1n7s:
- Domain d1n7sb1: 1n7s B:191-256 [80272]
  Other proteins in same PDB: d1n7sa1, d1n7sa2, d1n7sb2, d1n7sc1, d1n7sc2, d1n7sd1, d1n7sd2
  complex with synaptobrevin and SNAP-25 fragments
  complexed with ca, mpd

Domains for 1sfc:

3040310

Domain d1sfcb_: 1sfc B: [45644]
Other proteins in same PDB: d1sfca_, d1sfcc_, d1sfcd_, d1sfce_, d1sfcg_, d1sfch_, d1sfci_, d1sfck_, d1sfcl_
complex with synaptobrevin and SNAP-25 fragments
complexed with mpd, sr

3040311

Domain d1sfcf_: 1sfc F: [45648]
Other proteins in same PDB: d1sfca_, d1sfcc_, d1sfcd_, d1sfce_, d1sfcg_, d1sfch_, d1sfci_, d1sfck_, d1sfcl_
complex with synaptobrevin and SNAP-25 fragments
complexed with mpd, sr

3040312

Domain d1sfcj_: 1sfc J: [45652]
Other proteins in same PDB: d1sfca_, d1sfcc_, d1sfcd_, d1sfce_, d1sfcg_, d1sfch_, d1sfci_, d1sfck_, d1sfcl_
complex with synaptobrevin and SNAP-25 fragments
complexed with mpd, sr

Domain for 1urq:
- Domain d1urqb_: 1urq B: [107995]
  Other proteins in same PDB: d1urqa_, d1urqc_, d1urqd1, d1urqd2

More info for Protein Syntaxin 1A from h.1.15.1: SNARE fusion complex

Timeline for Protein Syntaxin 1A from h.1.15.1: SNARE fusion complex:

Protein Syntaxin 1A from h.1.15.1: SNARE fusion complex first appeared in SCOP 1.65
Protein Syntaxin 1A from h.1.15.1: SNARE fusion complex appears in SCOPe 2.07