Lineage for Fold h.1: Parallel coiled-coil

  1. Root: SCOPe 2.08
  2. Class h: Coiled coil proteins [57942] (7 folds)
  3. Fold h.1: Parallel coiled-coil [57943] (41 superfamilies)
    this is not a true fold; includes oligomers of shorter identical helices

Superfamilies:

  1. h.1.1: Triple coiled coil domain of C-type lectins [57944] (1 family) (S)
  2. h.1.2: Trimerization domain of TRAF [57953] (1 family) (S)
  3. h.1.3: Leucine zipper domain [57959] (2 families) (S)
  4. h.1.4: Inovirus (filamentous phage) major coat protein [57987] (1 family) (S)
  5. h.1.5: Tropomyosin [57997] (2 families) (S)
  6. h.1.6: Chicken cartilage matrix protein [58002] (1 family) (S)
  7. h.1.7: Assembly domain of cartilage oligomeric matrix protein [58006] (1 family) (S)
  8. h.1.8: Fibrinogen coiled-coil and central regions [58010] (2 families) (S)
  9. h.1.9: Coiled-coil domain of nucleotide exchange factor GrpE [58014] (1 family) (S)
  10. h.1.10: Coiled-coil dimerization domain from cortexillin I [58018] (1 family) (S)
  11. h.1.11: XRCC4, C-terminal oligomerization domain [58022] (2 families) (S)
  12. h.1.12: Delta-sleep-inducing peptide immunoreactive peptide [58026] (1 family) (S)
  13. h.1.13: Rotavirus nonstructural proteins [58030] (2 families) (S)
    not a true superfamily
  14. h.1.14: Multimerization domain of the phosphoprotein from sendai virus [58034] (1 family) (S)
  15. h.1.15: SNARE fusion complex [58038] (2 families) (S)
    tetrameric parallel coiled coil
  16. h.1.16: Outer membrane lipoprotein [58042] (1 family) (S)
  17. h.1.17: Fibritin [58046] (1 family) (S)
  18. h.1.18: N-terminal coiled coil domain from apc [58050] (1 family) (S)
  19. h.1.19: Tetrabrachion [58054] (1 family) (S)
  20. h.1.20: Intermediate filament protein, coiled coil region [64593] (2 families) (S)
  21. h.1.21: Eea1 homodimerisation domain [69979] (1 family) (S)
  22. h.1.22: Mitotic arrest deficient-like 1, Mad1 [75704] (1 family) (S)
  23. h.1.23: Dimerization motif of sir4 [90242] (1 family) (S)
  24. h.1.24: Head morphogenesis protein gp7 [90246] (1 family) (S)
  25. h.1.25: Troponin coil-coiled subunits [90250] (2 families) (S)
    form heterodimeric coiled coil
  26. h.1.26: Myosin rod fragments [90257] (2 families) (S)
  27. h.1.27: G protein-binding domain [103652] (2 families) (S)
  28. h.1.28: Geminin coiled-coil domain [111469] (2 families) (S)
  29. h.1.29: Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain [118370] (1 family) (S)
    tetrameric parallel coiled coil with a right-handed twist
  30. h.1.30: MPN010-like [144266] (1 family) (S)
    segmented trimeric coiled coil
  31. h.1.31: Eferin C-derminal domain-like [144270] (1 family) (S)
  32. h.1.32: Heterotrimerisation domain of extracellular hemoglobin linker subunits [144276] (1 family) (S)
  33. h.1.33: Sec2 N-terminal region [144284] (1 family) (S)
    dimeric coiled coil
  34. h.1.34: RILP dimerisation region [161256] (1 family) (S)
  35. h.1.35: Demethylase interaction domain of CoREST [267603] (1 family) (S)
    Includes N-terminal part of Pfam PF01448, ELM2 domain, which interacts with LSD1
  36. h.1.36: V-type ATPase peripheral stalk subunit E coiled coil [310578] (1 family) (S)
    Unusual right-handed coiled coil noted in PubMed 20173764
  37. h.1.37: V-type ATPase peripheral stalk subunit G coiled coil [310579] (1 family) (S)
    Unusual right-handed coiled coil noted in PubMed 20173764
  38. h.1.38: N-terminal linker of 6-deoxyerythronolide B synthase (DEBS) [310589] (1 family) (S)
  39. h.1.39: Proteasome regulatory subunits coiled coil regions [345933] (1 family) (S)
    Not a true superfamily
  40. h.1.40: Pre-mRNA splicing factor Prp19 coiled coil domain [345934] (2 families) (S)
    Pfam PF08606
  41. h.1.41: Pre-mRNA splicing factor Cwf7-like [345935] (1 family) (S)
    Pfam PF05700; mostly a long coiled coil with a few additional helices, partially disordered

More info for Fold h.1: Parallel coiled-coil

Timeline for Fold h.1: Parallel coiled-coil: