SCOPe 2.05: Species: Human (Homo sapiens) [TaxId: 9606]

Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.05
Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)
Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
multi-helical domains of various folds which is thought to unfold in the membrane
Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
Pfam PF00452
Protein Apoptosis regulator Bcl-xL [56856] (3 species)
Species Human (Homo sapiens) [TaxId:9606] [56857] (32 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

Domain(s) for 1bxl:
- Domain d1bxla_: 1bxl A: [43396]
Domain(s) for 1g5j:
- Domain d1g5ja_: 1g5j A: [43394]
  complex with peptide from Bad (CH B)
Domain(s) for 1lxl:
- Domain d1lxla_: 1lxl A: [43395]
Domain(s) for 1maz:
- Domain d1maza_: 1maz A: [43393]
Domain(s) for 1r2d:
- Domain d1r2da_: 1r2d A: [96864]
Domain(s) for 1r2e:
- Domain d1r2ea_: 1r2e A: [96865]
  mutant
Domain(s) for 1r2g:
- Domain d1r2ga_: 1r2g A: [96866]
  mutant
Domain(s) for 1r2h:
- Domain d1r2ha_: 1r2h A: [96867]
  mutant
Domain(s) for 1r2i:
- Domain d1r2ia_: 1r2i A: [96868]
  mutant
Domain(s) for 1ysg:
- Domain d1ysga_: 1ysg A: [123973]
  automated match to d1g5ja_
  complexed with 4fc, tn1
Domain(s) for 1ysi:
- Domain d1ysia_: 1ysi A: [123974]
  automated match to d1g5ja_
  complexed with n3b
Domain(s) for 1ysn:
- Domain d1ysna_: 1ysn A: [123980]
  automated match to d1g5ja_
  complexed with 43b
Domain(s) for 2b48:
- Domain d2b48a1: 2b48 A:1-196 [127816]
  automatically matched to d1maz__
Domain(s) for 2lpc:
- Domain d2lpca_: 2lpc A: [242960]
  automated match to d2o1ya1
Domain(s) for 2me8:
- Domain d2me8a_: 2me8 A: [256422]
  automated match to d1bxla_
Domain(s) for 2me9:
- Domain d2me9a_: 2me9 A: [257935]
  automated match to d1bxla_
Domain(s) for 2o1y:
- Domain d2o1ya_: 2o1y A: [138881]
  automated match to d1g5ja_
  complexed with 43b
Domain(s) for 2o2m:
- Domain d2o2ma_: 2o2m A: [243290]
  automated match to d4a1ua_
  complexed with li0
Domain(s) for 2o2n:
- Domain d2o2na_: 2o2n A: [243291]
  automated match to d4a1ua_
  complexed with liw
Domain(s) for 2p1l:
1. Domain d2p1la_: 2p1l A: [166945]
  automated match to d1g5ja_
2. Domain d2p1lc_: 2p1l C: [166946]
  automated match to d1g5ja_
3. Domain d2p1le_: 2p1l E: [166947]
  automated match to d1g5ja_
4. Domain d2p1lg_: 2p1l G: [166948]
  automated match to d1g5ja_
Domain(s) for 2pon:
- Domain d2ponb_: 2pon B: [149723]
  automated match to d3sp7a_
Domain(s) for 2yxj:
1. Domain d2yxja_: 2yxj A: [170913]
  automated match to d1g5ja_
  complexed with cl, gol, n3c
2. Domain d2yxjb_: 2yxj B: [170914]
  automated match to d1g5ja_
  complexed with cl, gol, n3c
Domain(s) for 3cva:
- Domain d3cvax_: 3cva X: [173494]
  automated match to d1bxla_
  mutant
Domain(s) for 3io8:
1. Domain d3io8a_: 3io8 A: [178474]
  automated match to d1g5ja_
  complexed with zn
2. Domain d3io8c_: 3io8 C: [178475]
  automated match to d1g5ja_
  complexed with zn
Domain(s) for 3pl7:
1. Domain d3pl7a_: 3pl7 A: [183827]
  automated match to d1g5ja_
2. Domain d3pl7b_: 3pl7 B: [183828]
  automated match to d1g5ja_
Domain(s) for 3qkd:
1. Domain d3qkda_: 3qkd A: [184464]
  automated match to d1g5ja_
  complexed with cl, gol, hi0
2. Domain d3qkdb_: 3qkd B: [184465]
  automated match to d1g5ja_
  complexed with cl, gol, hi0
Domain(s) for 3sp7:
- Domain d3sp7a_: 3sp7 A: [195002]
  automated match to d2o1ya1
  complexed with 03b, act, zn
Domain(s) for 3spf:
- Domain d3spfa_: 3spf A: [195036]
  automated match to d2o1ya1
  complexed with b50, gol
Domain(s) for 3wiz:
1. Domain d3wiza_: 3wiz A: [233972]
  automated match to d1g5ja_
  complexed with lc6, po4
2. Domain d3wizb_: 3wiz B: [233973]
  automated match to d1g5ja_
  complexed with lc6, po4
Domain(s) for 4ehr:
- Domain d4ehra_: 4ehr A: [195229]
  automated match to d2o1ya1
  complexed with 0q5, imd
Domain(s) for 4ppi:
- Domain d4ppia_: 4ppi A: [269752]
  automated match to d2o1ya_
  complexed with gol
Domain(s) for 4tuh:
1. Domain d4tuha_: 4tuh A: [260442]
  automated match to d1ysga_
  complexed with 38h, act, edo
2. Domain d4tuhb_: 4tuh B: [263918]
  automated match to d2o1ya_
  complexed with 38h, act, edo
3. Domain d4tuhc_: 4tuh C: [263919]
  automated match to d2o1ya_
  complexed with 38h, act, edo
4. Domain d4tuhd_: 4tuh D: [263920]
  automated match to d2o1ya_
  complexed with 38h, act, edo
5. Domain d4tuhe_: 4tuh E: [263921]
  automated match to d2o1ya_
  complexed with 38h, act, edo
6. Domain d4tuhf_: 4tuh F: [263922]
  automated match to d2o1ya_
  complexed with 38h, act, edo
7. Domain d4tuhg_: 4tuh G: [263923]
  automated match to d2o1ya_
  complexed with 38h, act, edo
8. Domain d4tuhh_: 4tuh H: [263924]
  automated match to d2o1ya_
  complexed with 38h, act, edo

More info for Species Human (Homo sapiens) [TaxId:9606] from f.1.4.1 Apoptosis regulator Bcl-xL

Timeline for Species Human (Homo sapiens) [TaxId:9606] from f.1.4.1 Apoptosis regulator Bcl-xL:

Species Human (Homo sapiens) [TaxId:9606] from f.1.4.1 Apoptosis regulator Bcl-xL first appeared (with stable ids) in SCOP 1.55
Species Human (Homo sapiens) [TaxId:9606] from f.1.4.1 Apoptosis regulator Bcl-xL appears in SCOPe 2.04
Species Human (Homo sapiens) [TaxId:9606] from f.1.4.1 Apoptosis regulator Bcl-xL appears in SCOPe 2.06
Species Human (Homo sapiens) [TaxId:9606] from f.1.4.1 Apoptosis regulator Bcl-xL appears in the current release, SCOPe 2.08