Lineage for Protein: Apoptosis regulator Bcl-xL

  1. Root: SCOPe 2.05
  2. 1955192Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)
  3. 1955193Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 1955265Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 1955266Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 1955272Protein Apoptosis regulator Bcl-xL [56856] (3 species)

Species:

  1. 1955273Human (Homo sapiens) [TaxId:9606] [56857] (32 PDB entries)
    1. Domain for 1bxl:
    2. Domain for 1g5j:
    3. Domain for 1lxl:
    4. Domain for 1maz:
    5. Domain for 1r2d:
    6. Domain for 1r2e:
    7. Domain for 1r2g:
    8. Domain for 1r2h:
    9. Domain for 1r2i:
    10. Domain for 1ysg:
    11. Domain for 1ysi:
    12. Domain for 1ysn:
    13. Domain for 2b48:
    14. Domain for 2lpc:
    15. Domain for 2me8:
    16. Domain for 2me9:
    17. Domain for 2o1y:
    18. Domain for 2o2m:
    19. Domain for 2o2n:
    20. Domains for 2p1l:
      1. 1955296Domain d2p1la_: 2p1l A: [166945]
        automated match to d1g5ja_
      2. 1955297Domain d2p1lc_: 2p1l C: [166946]
        automated match to d1g5ja_
      3. 1955298Domain d2p1le_: 2p1l E: [166947]
        automated match to d1g5ja_
      4. 1955299Domain d2p1lg_: 2p1l G: [166948]
        automated match to d1g5ja_
    21. Domain for 2pon:
    22. Domains for 2yxj:
      1. 1955289Domain d2yxja_: 2yxj A: [170913]
        automated match to d1g5ja_
        complexed with cl, gol, n3c
      2. 1955290Domain d2yxjb_: 2yxj B: [170914]
        automated match to d1g5ja_
        complexed with cl, gol, n3c
    23. Domain for 3cva:
    24. Domains for 3io8:
      1. 1955294Domain d3io8a_: 3io8 A: [178474]
        automated match to d1g5ja_
        complexed with zn
      2. 1955295Domain d3io8c_: 3io8 C: [178475]
        automated match to d1g5ja_
        complexed with zn
    25. Domains for 3pl7:
      1. 1955303Domain d3pl7a_: 3pl7 A: [183827]
        automated match to d1g5ja_
      2. 1955304Domain d3pl7b_: 3pl7 B: [183828]
        automated match to d1g5ja_
    26. Domains for 3qkd:
      1. 1955285Domain d3qkda_: 3qkd A: [184464]
        automated match to d1g5ja_
        complexed with cl, gol, hi0
      2. 1955286Domain d3qkdb_: 3qkd B: [184465]
        automated match to d1g5ja_
        complexed with cl, gol, hi0
    27. Domain for 3sp7:
    28. Domain for 3spf:
    29. Domains for 3wiz:
      1. 1955301Domain d3wiza_: 3wiz A: [233972]
        automated match to d1g5ja_
        complexed with lc6, po4
      2. 1955302Domain d3wizb_: 3wiz B: [233973]
        automated match to d1g5ja_
        complexed with lc6, po4
    30. Domain for 4ehr:
    31. Domain for 4ppi:
    32. Domains for 4tuh:
      1. 1955277Domain d4tuha_: 4tuh A: [260442]
        automated match to d1ysga_
        complexed with 38h, act, edo
      2. 1955278Domain d4tuhb_: 4tuh B: [263918]
        automated match to d2o1ya_
        complexed with 38h, act, edo
      3. 1955279Domain d4tuhc_: 4tuh C: [263919]
        automated match to d2o1ya_
        complexed with 38h, act, edo
      4. 1955280Domain d4tuhd_: 4tuh D: [263920]
        automated match to d2o1ya_
        complexed with 38h, act, edo
      5. 1955281Domain d4tuhe_: 4tuh E: [263921]
        automated match to d2o1ya_
        complexed with 38h, act, edo
      6. 1955282Domain d4tuhf_: 4tuh F: [263922]
        automated match to d2o1ya_
        complexed with 38h, act, edo
      7. 1955283Domain d4tuhg_: 4tuh G: [263923]
        automated match to d2o1ya_
        complexed with 38h, act, edo
      8. 1955284Domain d4tuhh_: 4tuh H: [263924]
        automated match to d2o1ya_
        complexed with 38h, act, edo
  2. 1955321Mouse (Mus musculus) [TaxId:10090] [103423] (9 PDB entries)
    1. Domain for 1pq0:
    2. Domain for 1pq1:
    3. Domain for 3ihc:
    4. Domain for 3ihd:
    5. Domains for 3ihf:
      1. 1955327Domain d3ihfa_: 3ihf A: [211686]
        automated match to d1r2da_
        mutant
      2. 1955328Domain d3ihfb_: 3ihf B: [211687]
        automated match to d1r2da_
        mutant
      3. 1955329Domain d3ihfc_: 3ihf C: [211688]
        automated match to d1r2da_
        mutant
      4. 1955330Domain d3ihfd_: 3ihf D: [211689]
        automated match to d1r2da_
        mutant
    6. Domain for 3iig:
    7. Domain for 3iih:
    8. Domains for 3ilb:
      1. 1955332Domain d3ilba_: 3ilb A: [211817]
        automated match to d1r2da_
        mutant
      2. 1955333Domain d3ilbn_: 3ilb N: [211818]
        automated match to d1r2da_
        mutant
    9. Domain for 3ilc:
  3. 1955335Norway rat (Rattus norvegicus) [TaxId:10116] [56858] (1 PDB entry)

More info for Protein Apoptosis regulator Bcl-xL from f.1.4.1: Bcl-2 inhibitors of programmed cell death

Timeline for Protein Apoptosis regulator Bcl-xL from f.1.4.1: Bcl-2 inhibitors of programmed cell death: