PDB entry 3io8

View 3io8 on RCSB PDB site
Description: BimL12F in complex with Bcl-xL
Class: apoptosis
Keywords: helical bundle, Bcl-2-like fold, Alternative splicing, Apoptosis, Membrane, Mitochondrion, Nucleus, Transmembrane, Phosphoprotein
Deposited on 2009-08-14, released 2009-09-01
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-12-29, with a file datestamp of 2009-12-24.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.187
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bcl-2-like protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL2L1, BCL2L, BCLX
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (5-30)
      • expression tag (1-4)
    • Uniprot Q07817 (31-End)
    Domains in SCOPe 2.05: d3io8a_
  • Chain 'B':
    Compound: Bcl-2-like protein 11
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43521 (Start-25)
      • engineered (11)
  • Chain 'C':
    Compound: Bcl-2-like protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL2L1, BCL2L, BCLX
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (5-30)
      • expression tag (0-4)
    • Uniprot Q07817 (31-End)
    Domains in SCOPe 2.05: d3io8c_
  • Chain 'D':
    Compound: Bcl-2-like protein 11
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43521
      • engineered (11)
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3io8A (A:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygnnaaaesrkgqer

    Sequence, based on observed residues (ATOM records): (download) 
    >3io8A (A:)
plgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdllhit
pgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawmatyln
dhlepwiqenggwdtfvelygn

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3io8C (C:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygnnaaaesrkgqer

    Sequence, based on observed residues (ATOM records): (download) 
    >3io8C (C:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygn

  • Chain 'D':
    No sequence available.