Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.8: (Trans)glycosidases [51445] (15 families) |
Family c.1.8.1: Amylase, catalytic domain [51446] (26 proteins) members of the family may contain various insert subdomains in alpha-amylases and closer relatives this domain is usually followed by a common all-beta domain |
1,4-alpha-glucan branching enzyme, central domain [82244] (1 species) |
Species Escherichia coli [TaxId:562] [82245] (1 PDB entry) |
4-alpha-glucanotransferase [75062] (1 species) |
Species Thermotoga maritima [TaxId:2336] [75063] (2 PDB entries) |
A4 beta-galactosidase [82246] (1 species) the catalytic domain is very similar to that of the bacterial beta-amylase; but contains a typical alpha-amylase extra domain |
Species Thermus thermophilus [TaxId:274] [82247] (2 PDB entries) |
Amylomaltase MalQ [51478] (3 species) 4-alpha-glucanotransferase; single-domain amylase with several insertions in the common fold |
Species Aquifex aeolicus [TaxId:63363] [141770] (1 PDB entry) Uniprot O66937 1-485 |
Species Potato (Solanum tuberosum) [TaxId:4113] [141771] (4 PDB entries) Uniprot Q06801 54-576 |
Species Thermus aquaticus [TaxId:271] [51479] (4 PDB entries) synonym: Thermus thermophilus |
Amylosucrase [69384] (1 species) |
Species Neisseria polysaccharea [TaxId:489] [69385] (10 PDB entries) |
Animal alpha-amylase [51458] (3 species) contains Ca2+-binding subdomain, residues 100-170 |
Species Human (Homo sapiens) [TaxId:9606] [51460] (55 PDB entries) Uniprot P04746 16-511 ! SQ 04746 |
Species Pig (Sus scrofa) [TaxId:9823] [51459] (13 PDB entries) |
Species Yellow mealworm (Tenebrio molitor), larva [TaxId:7067] [51461] (4 PDB entries) |
Bacterial alpha-amylase [51447] (10 species) |
Species Bacillus licheniformis [TaxId:1402] [51448] (9 PDB entries) |
Species Bacillus sp. 707 [TaxId:1416] [117366] (4 PDB entries) Uniprot P19571 38-518 |
Species Bacillus sp., ksm-k38 [TaxId:1409] [89463] (6 PDB entries) |
Species Bacillus stearothermophilus [TaxId:1422] [51451] (1 PDB entry) |
Species Bacillus subtilis [TaxId:1423] [51450] (2 PDB entries) Uniprot P00691 |
Species Chimera (Bacillus amyloliquefaciens) and (Bacillus licheniformis) [TaxId:1390] [63903] (4 PDB entries) the N-terminal 300 residues are from B. amyloliquefaciens |
Species Halothermothrix orenii [TaxId:31909] [141767] (1 PDB entry) Uniprot Q8GPL8 28-436 |
Species Pseudoalteromonas haloplanktis [TaxId:228] [51449] (9 PDB entries) |
Species Pyrococcus woesei [TaxId:2262] [89464] (3 PDB entries) |
Bacterial beta-amylase [51485] (1 species) protein contains additional starch-binding domain |
Species Bacillus cereus [TaxId:1396] [51486] (11 PDB entries) |
beta-Amylase [51481] (3 species) Common fold covers whole protein structure |
Species Barley (Hordeum vulgare) [TaxId:4513] [51483] (1 PDB entry) |
Species Soybean (Glycine max) [TaxId:3847] [51482] (18 PDB entries) Uniprot P10538 |
Species Sweet potato (Ipomoea batatas) [TaxId:4120] [51484] (3 PDB entries) |
Cyclodextrin glycosyltransferase [51452] (5 species) contains two more all-beta domains, one is Immunoglobulin-like and the other is trasthyretin-like |
Species Bacillus circulans, different strains [TaxId:1397] [51453] (36 PDB entries) |
Species Bacillus sp. 1011, alkaliphilic [TaxId:1410] [51456] (8 PDB entries) Uniprot P05618 |
Species Bacillus stearothermophilus [TaxId:1422] [51454] (1 PDB entry) |
Species Bacillus stearothermophilus, maltogenic alpha-amylase [TaxId:1422] [51455] (2 PDB entries) |
Species Thermoanaerobacterium thermosulfurigenes, EM1 [TaxId:33950] [51457] (4 PDB entries) |
Cyclomaltodextrinase, central domain [102058] (1 species) protein shares similar domain organization with maltogenic amylases but differs in the spatial arrangement of its domains |
Species Flavobacterium sp. 92 [TaxId:197856] [102059] (6 PDB entries) |
Fungal alpha-amylases [51462] (2 species) |
Species Aspergillus niger, acid amylase [TaxId:5061] [51463] (1 PDB entry) |
Species Aspergillus oryzae, Taka-amylase [TaxId:5062] [51464] (8 PDB entries) |
G4-amylase (1,4-alpha-D-glucan maltotetrahydrolase) [51472] (1 species) |
Species Pseudomonas stutzeri [TaxId:316] [51473] (9 PDB entries) |
Glycosyltrehalose trehalohydrolase, central domain [51468] (2 species) contains an additional N-terminal domain |
Species Deinococcus radiodurans [TaxId:1299] [141769] (9 PDB entries) Uniprot Q9RX51 111-528 |
Species Sulfolobus solfataricus, km1 [TaxId:2287] [51469] (8 PDB entries) |
Isoamylase, central domain [51470] (1 species) |
Species Pseudomonas amyloderamosa [TaxId:32043] [51471] (1 PDB entry) |
Isomaltulose synthase PalI [89466] (2 species) |
Species Erwinia rhapontici [TaxId:55212] [254869] (5 PDB entries) |
Species Klebsiella sp., lx3 [TaxId:576] [89467] (1 PDB entry) |
Maltogenic amylase, central domain [51465] (4 species) contains an additional N-terminal domain |
Species Bacillus sp., cyclomaltodextrinase [TaxId:1409] [75060] (1 PDB entry) |
Species Thermoactinomyces vulgaris, TVAI [TaxId:2026] [75061] (8 PDB entries) |
Species Thermoactinomyces vulgaris, TVAII [TaxId:2026] [51467] (12 PDB entries) |
Species Thermus sp. [TaxId:275] [51466] (2 PDB entries) |
Maltooligosyl trehalose synthase [82242] (1 species) elaborated with several large insertions in the common fold |
Species Sulfolobus acidocaldarius [TaxId:2285] [82243] (1 PDB entry) |
Maltosyltransferase [63904] (1 species) similar to bacterial alpha-amylase; contains larger insertion domain |
Species Thermotoga maritima [TaxId:2336] [63905] (2 PDB entries) |
Melibiase [75064] (4 species) |
Species Chicken (Gallus gallus) [TaxId:9031] [75065] (2 PDB entries) alpha-N-acetylgalactosaminidase |
Species Human (Homo sapiens) [TaxId:9606] [102062] (21 PDB entries) alpha-galactosidase A |
Species Rice (Oryza sativa) [TaxId:4530] [89468] (1 PDB entry) alpha-galactosidase |
Species Trichoderma reesei [TaxId:51453] [110349] (2 PDB entries) Alpha-galactosidase agl1 Uniprot Q92456 |
Neopullulanase, central domain [82240] (1 species) homologous to Maltogenic amylase |
Species Bacillus stearothermophilus [TaxId:1422] [82241] (4 PDB entries) |
Oligo-1,6, glucosidase [51476] (1 species) |
Species Bacillus cereus [TaxId:1396] [51477] (1 PDB entry) |
Plant alpha-amylase [51474] (2 species) |
Species Barley (Hordeum vulgare), AMY1 isozyme [TaxId:4513] [89465] (7 PDB entries) |
Species Barley (Hordeum vulgare), seeds, AMY2 isozyme [TaxId:4513] [51475] (3 PDB entries) |
Pullulanase PulA [159381] (1 species) |
Species Klebsiella pneumoniae [TaxId:573] [159382] (6 PDB entries) Uniprot P07206 410-972 |
Sucrose phosphorylase [102060] (1 species) sequence and close structural relationship to amylosucrase; variations in the C-terminal domain fold |
Species Bifidobacterium adolescentis [TaxId:1680] [102061] (2 PDB entries) |
automated matches [190099] (31 species) not a true protein |
Species Bacillus halmapalus [TaxId:79882] [255187] (2 PDB entries) |
Species Bacillus sp. [225222] (1 PDB entry) |
Species Bacillus sp. [TaxId:535911] [225472] (1 PDB entry) |
Species Bacillus subtilis [TaxId:224308] [228099] (5 PDB entries) |
Species Barley (Hordeum vulgare) [TaxId:4513] [255684] (11 PDB entries) |
Species Bifidobacterium adolescentis [TaxId:1680] [255183] (4 PDB entries) |
Species Bifidobacterium adolescentis [TaxId:367928] [365787] (1 PDB entry) |
Species Escherichia coli [TaxId:331111] [311496] (3 PDB entries) |
Species Escherichia coli [TaxId:562] [270950] (4 PDB entries) |
Species Fungus (Aspergillus oryzae) [TaxId:5062] [393398] (1 PDB entry) |
Species Geobacillus stearothermophilus [TaxId:1422] [311444] (1 PDB entry) |
Species Human (Homo sapiens) [TaxId:9606] [225770] (14 PDB entries) |
Species Klebsiella pneumoniae [TaxId:573] [359376] (10 PDB entries) |
Species Listeria monocytogenes [TaxId:169963] [277525] (1 PDB entry) |
Species Neisseria polysaccharea [TaxId:489] [226280] (7 PDB entries) |
Species Nicotiana benthamiana [TaxId:4100] [351546] (1 PDB entry) |
Species Oryzias latipes [TaxId:8090] [226401] (1 PDB entry) |
Species Pelomonas saccharophila [TaxId:304] [377973] (4 PDB entries) |
Species Pig (Sus scrofa) [TaxId:9823] [225875] (3 PDB entries) |
Species Protaminobacter rubrum [TaxId:126825] [225680] (2 PDB entries) |
Species Pseudomonas mesoacidophila [TaxId:265293] [224875] (9 PDB entries) |
Species Pyrococcus woesei [TaxId:2262] [226292] (1 PDB entry) |
Species Soybean (Glycine max) [TaxId:3847] [186821] (2 PDB entries) |
Species Streptococcus agalactiae [TaxId:1311] [402353] (1 PDB entry) |
Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [278910] (6 PDB entries) |
Species Thermoactinomyces vulgaris [TaxId:2026] [254920] (8 PDB entries) |
Species Thermus aquaticus [TaxId:271] [328921] (1 PDB entry) |
Species Thermus brockianus [TaxId:56956] [189542] (1 PDB entry) |
Species Thermus thermophilus [TaxId:274] [188525] (3 PDB entries) |
Species Wheat (Triticum aestivum) [TaxId:4565] [361430] (1 PDB entry) |
Timeline for Family c.1.8.1: Amylase, catalytic domain: