SCOPe 2.08: Protein: Animal alpha-amylase

Lineage for Protein: Animal alpha-amylase

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.8: (Trans)glycosidases [51445] (15 families)

Family c.1.8.1: Amylase, catalytic domain [51446] (26 proteins)
members of the family may contain various insert subdomains
in alpha-amylases and closer relatives this domain is usually followed by a common all-beta domain

Protein Animal alpha-amylase [51458] (3 species)
contains Ca2+-binding subdomain, residues 100-170

Species:

Human (Homo sapiens) [TaxId:9606] [51460] (55 PDB entries)
Uniprot P04746 16-511 ! SQ 04746

Domain for 1b2y:
- Domain d1b2ya2: 1b2y A:2-403 [28759]
  Other proteins in same PDB: d1b2ya1
  complexed with ca, cl, pca
  has additional subdomain(s) that are not in the common domain
Domain for 1bsi:
- Domain d1bsia2: 1bsi A:2-403 [28757]
  Other proteins in same PDB: d1bsia1, d1bsia3
  complexed with ca, cl, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1c8q:
- Domain d1c8qa2: 1c8q A:1-403 [59088]
  Other proteins in same PDB: d1c8qa1
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 1cpu:
- Domain d1cpua2: 1cpu A:1-403 [28758]
  Other proteins in same PDB: d1cpua1
  complexed with ca, cl, hmc, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1hny:
- Domain d1hnya2: 1hny A:2-403 [28756]
  Other proteins in same PDB: d1hnya1, d1hnya3
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 1jxj:
- Domain d1jxja2: 1jxj A:1-403 [63315]
  Other proteins in same PDB: d1jxja1
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 1jxk:
- Domain d1jxka2: 1jxk A:1-403 [63317]
  Other proteins in same PDB: d1jxka1
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 1kb3:
- Domain d1kb3a2: 1kb3 A:1-403 [72270]
  Other proteins in same PDB: d1kb3a1
  complexed with ca, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1kbb:
- Domain d1kbba2: 1kbb A:1-403 [72276]
  Other proteins in same PDB: d1kbba1
  complexed with ca, cl; mutant
  has additional subdomain(s) that are not in the common domain
Domain for 1kbk:
- Domain d1kbka2: 1kbk A:1-403 [72283]
  Other proteins in same PDB: d1kbka1
  complexed with ca, cl, nag; mutant
  has additional subdomain(s) that are not in the common domain
Domain for 1kgu:
- Domain d1kgua2: 1kgu A:1-403 [68599]
  Other proteins in same PDB: d1kgua1
  complexed with ca
  has additional subdomain(s) that are not in the common domain
Domain for 1kgw:
- Domain d1kgwa2: 1kgw A:1-403 [68601]
  Other proteins in same PDB: d1kgwa1
  complexed with ca, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1kgx:
- Domain d1kgxa2: 1kgx A:1-403 [68603]
  Other proteins in same PDB: d1kgxa1
  complexed with ca, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1mfu:
- Domain d1mfua2: 1mfu A:1-403 [79048]
  Other proteins in same PDB: d1mfua1
  complexed with ca, cl, glc, hmc; mutant
  has additional subdomain(s) that are not in the common domain
Domain for 1mfv:
- Domain d1mfva2: 1mfv A:2-403 [79050]
  Other proteins in same PDB: d1mfva1, d1mfva3
  complexed with ca, cl, hmc
  has additional subdomain(s) that are not in the common domain
Domain for 1nm9:
- Domain d1nm9a2: 1nm9 A:1-403 [91975]
  Other proteins in same PDB: d1nm9a1
  complexed with ca, cl, glc, hmc; mutant
  has additional subdomain(s) that are not in the common domain
Domain for 1q4n:
- Domain d1q4nx2: 1q4n X:1-403 [95808]
  Other proteins in same PDB: d1q4nx1
  complexed with ca, cl, tam
  has additional subdomain(s) that are not in the common domain
Domain for 1smd:
- Domain d1smda2: 1smd A:2-403 [28755]
  Other proteins in same PDB: d1smda1, d1smda3
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 1u2y:
- Domain d1u2ya2: 1u2y A:1-403 [107625]
  Other proteins in same PDB: d1u2ya1
  complexed with ca, cl, gox, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1u30:
- Domain d1u30a2: 1u30 A:1-403 [107630]
  Other proteins in same PDB: d1u30a1
  complexed with ca, cl, gox, lag, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1u33:
- Domain d1u33a2: 1u33 A:1-403 [107633]
  Other proteins in same PDB: d1u33a1
  complexed with ca, cl, lm2, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1xcw:
- Domain d1xcwa2: 1xcw A:1-403 [115135]
  Other proteins in same PDB: d1xcwa1
  complexed with ca, cl, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1xcx:
- Domain d1xcxa2: 1xcx A:1-403 [115137]
  Other proteins in same PDB: d1xcxa1
  complexed with ca, cl, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1xd0:
- Domain d1xd0a2: 1xd0 A:1-403 [115139]
  Other proteins in same PDB: d1xd0a1
  complexed with are, ca, cl, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1xd1:
- Domain d1xd1a2: 1xd1 A:1-403 [115141]
  Other proteins in same PDB: d1xd1a1
  complexed with 6sa, ca, cl, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1z32:
- Domain d1z32x2: 1z32 X:1-408 [124395]
  Other proteins in same PDB: d1z32x1
  automated match to d1jxka2
  complexed with agl, ca, cl, glc, hmc
  has additional subdomain(s) that are not in the common domain
Domain for 2cpu:
- Domain d2cpua2: 2cpu A:1-403 [63335]
  Other proteins in same PDB: d2cpua1
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 2qmk:
- Domain d2qmka2: 2qmk A:1-403 [150885]
  Other proteins in same PDB: d2qmka1
  automated match to d1hnya2
  complexed with ca, nag, no2
  has additional subdomain(s) that are not in the common domain
Domain for 2qv4:
- Domain d2qv4a2: 2qv4 A:1-403 [151385]
  Other proteins in same PDB: d2qv4a1
  automated match to d1hnya2
  complexed with ca, nag, no2, qv4
  has additional subdomain(s) that are not in the common domain
Domain for 3bai:
- Domain d3baia2: 3bai A:1-403 [155031]
  Other proteins in same PDB: d3baia1
  automated match to d1hnya2
  complexed with ca, nag, no3
  has additional subdomain(s) that are not in the common domain
Domain for 3baj:
- Domain d3baja2: 3baj A:1-403 [155033]
  Other proteins in same PDB: d3baja1
  automated match to d1hnya2
  complexed with are, ca, nag, no3
  has additional subdomain(s) that are not in the common domain
Domain for 3bak:
- Domain d3baka2: 3bak A:1-408 [155035]
  Other proteins in same PDB: d3baka1
  automated match to d1jxka2
  complexed with ca, nag, no3; mutant
  has additional subdomain(s) that are not in the common domain
Domain for 3baw:
- Domain d3bawa2: 3baw A:1-403 [155040]
  Other proteins in same PDB: d3bawa1
  automated match to d1hnya2
  complexed with azi, ca, cl, na, nag
  has additional subdomain(s) that are not in the common domain
Domain for 3bax:
- Domain d3baxa2: 3bax A:1-408 [155042]
  Other proteins in same PDB: d3baxa1
  automated match to d1jxka2
  complexed with azi, ca, cl, na, nag
  has additional subdomain(s) that are not in the common domain
Domain for 3bay:
- Domain d3baya2: 3bay A:1-408 [155044]
  Other proteins in same PDB: d3baya1
  automated match to d1jxka2
  complexed with are, ca, nag, no3
  has additional subdomain(s) that are not in the common domain
Domain for 3blk:
- Domain d3blka1: 3blk A:1-403 [208655]
  Other proteins in same PDB: d3blka2
  automated match to d1jfha2
  complexed with ca, cl, hmc
  has additional subdomain(s) that are not in the common domain
Domain for 3blp:
- Domain d3blpx1: 3blp X:1-403 [208657]
  Other proteins in same PDB: d3blpx2
  automated match to d1jfha2
  complexed with ca, cl, hmc
  has additional subdomain(s) that are not in the common domain
Domain for 3cpu:
- Domain d3cpua2: 3cpu A:1-403 [63337]
  Other proteins in same PDB: d3cpua1
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 3ij7:
- Domain d3ij7a1: 3ij7 A:1-403 [211717]
  Other proteins in same PDB: d3ij7a2
  automated match to d1hnya2
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 3ij8:
- Domain d3ij8a1: 3ij8 A:1-403 [211719]
  Other proteins in same PDB: d3ij8a2
  automated match to d1hnya2
  complexed with b0d, b9d, ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 3ij9:
- Domain d3ij9a1: 3ij9 A:1-403 [211721]
  Other proteins in same PDB: d3ij9a2
  automated match to d1hnya2
  complexed with b0d, ca, cl
  has additional subdomain(s) that are not in the common domain

Domain for 3old:

Domain d3olda1: 3old A:2-403 [214428]
Other proteins in same PDB: d3olda2
automated match to d1jfha2
complexed with aci, ca, cl, mpd, nag, pca, so4
has additional subdomain(s) that are not in the common domain

Domain for 3ole:

Domain d3olea1: 3ole A:2-403 [214430]
Other proteins in same PDB: d3olea2
automated match to d1jfha2
complexed with aci, ca, cl, mpd, nag, pca, so4
has additional subdomain(s) that are not in the common domain

Domain for 3olg:

Domain d3olga1: 3olg A:2-403 [214432]
Other proteins in same PDB: d3olga2
automated match to d1jfha2
complexed with ca, cl, glc, hsd, pca, so4
has additional subdomain(s) that are not in the common domain

Domain for 3oli:

Domain d3olia1: 3oli A:2-403 [214436]
Other proteins in same PDB: d3olia2
automated match to d1jfha2
complexed with bgc, ca, cl, hsd, mpd, pca, so4
has additional subdomain(s) that are not in the common domain

Domain for 4gqq:
- Domain d4gqqa1: 4gqq A:1-403 [222090]
  Other proteins in same PDB: d4gqqa2
  automated match to d1hnya2
  complexed with 0xr, ca, cl, nag
  has additional subdomain(s) that are not in the common domain
Domain for 4gqr:
- Domain d4gqra1: 4gqr A:1-403 [222092]
  Other proteins in same PDB: d4gqra2
  automated match to d1hnya2
  complexed with ca, cl, myc, nag
  has additional subdomain(s) that are not in the common domain
Domain for 4w93:
- Domain d4w93a1: 4w93 A:1-403 [274977]
  Other proteins in same PDB: d4w93a2
  automated match to d1hnya2
  complexed with 3l9, ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 4x9y:
- Domain d4x9ya1: 4x9y A:1-403 [269160]
  Other proteins in same PDB: d4x9ya2
  automated match to d1hnya2
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 5e0f:
- Domain d5e0fa1: 5e0f A:1-403 [322162]
  Other proteins in same PDB: d5e0fa2
  automated match to d1hnya2
  complexed with 5j7, ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 5emy:
- Domain d5emya1: 5emy A:1-403 [319260]
  Other proteins in same PDB: d5emya2
  automated match to d1hnya2
  complexed with 5qp, ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 5td4:
- Domain d5td4a1: 5td4 A:1-403 [324741]
  Other proteins in same PDB: d5td4a2
  automated match to d2cpua2
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 5u3a:
- Domain d5u3aa1: 5u3a A:1-403 [342403]
  Other proteins in same PDB: d5u3aa2
  automated match to d1hnya2
  complexed with ca, cl, nag
  has additional subdomain(s) that are not in the common domain
Domain for 6obx:
- Domain d6obxa1: 6obx A:1-403 [380488]
  Other proteins in same PDB: d6obxa2
  automated match to d1hnya2
  complexed with ca, cl, mpd, nag, zxu
  has additional subdomain(s) that are not in the common domain
Domain for 6ocn:
- Domain d6ocna1: 6ocn A:1-403 [380428]
  Other proteins in same PDB: d6ocna2
  automated match to d1hnya2
  complexed with ca, cl, nag, zxy
  has additional subdomain(s) that are not in the common domain

Pig (Sus scrofa) [TaxId:9823] [51459] (13 PDB entries)

Domain for 1bvn:
- Domain d1bvnp2: 1bvn P:1-403 [28754]
  Other proteins in same PDB: d1bvnp1, d1bvnt_
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 1dhk:
- Domain d1dhka2: 1dhk A:1-403 [28748]
  Other proteins in same PDB: d1dhka1, d1dhkb_
  complexed with ca, cl, nag
  has additional subdomain(s) that are not in the common domain
Domain for 1hx0:
- Domain d1hx0a2: 1hx0 A:1-403 [61347]
  Other proteins in same PDB: d1hx0a1
  complexed with ca, cl, edo
  has additional subdomain(s) that are not in the common domain
Domain for 1jfh:
- Domain d1jfha2: 1jfh A:1-403 [28749]
  Other proteins in same PDB: d1jfha1
  complexed with ca, cl, hg
  has additional subdomain(s) that are not in the common domain

Domains for 1kxq:

Domain d1kxqa2: 1kxq A:1-403 [73164]
Other proteins in same PDB: d1kxqa1, d1kxqb1, d1kxqc1, d1kxqd1, d1kxqe_, d1kxqf_, d1kxqg_, d1kxqh_
complexed with ca, cl
has additional subdomain(s) that are not in the common domain

Domain d1kxqb2: 1kxq B:1-403 [73166]
Other proteins in same PDB: d1kxqa1, d1kxqb1, d1kxqc1, d1kxqd1, d1kxqe_, d1kxqf_, d1kxqg_, d1kxqh_
complexed with ca, cl
has additional subdomain(s) that are not in the common domain

Domain d1kxqc2: 1kxq C:1-403 [73168]
Other proteins in same PDB: d1kxqa1, d1kxqb1, d1kxqc1, d1kxqd1, d1kxqe_, d1kxqf_, d1kxqg_, d1kxqh_
complexed with ca, cl
has additional subdomain(s) that are not in the common domain

Domain d1kxqd2: 1kxq D:1-403 [73170]
Other proteins in same PDB: d1kxqa1, d1kxqb1, d1kxqc1, d1kxqd1, d1kxqe_, d1kxqf_, d1kxqg_, d1kxqh_
complexed with ca, cl
has additional subdomain(s) that are not in the common domain

Domains for 1kxt:
1. Domain d1kxta2: 1kxt A:1-403 [73178]
  Other proteins in same PDB: d1kxta1, d1kxtb_, d1kxtc1, d1kxtd_, d1kxte1, d1kxtf_
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
2. Domain d1kxtc2: 1kxt C:1-403 [73181]
  Other proteins in same PDB: d1kxta1, d1kxtb_, d1kxtc1, d1kxtd_, d1kxte1, d1kxtf_
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
3. Domain d1kxte2: 1kxt E:1-403 [73184]
  Other proteins in same PDB: d1kxta1, d1kxtb_, d1kxtc1, d1kxtd_, d1kxte1, d1kxtf_
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domains for 1kxv:
1. Domain d1kxva2: 1kxv A:1-403 [73187]
  Other proteins in same PDB: d1kxva1, d1kxvb1, d1kxvc_, d1kxvd_
  has additional subdomain(s) that are not in the common domain
2. Domain d1kxvb2: 1kxv B:1-403 [73189]
  Other proteins in same PDB: d1kxva1, d1kxvb1, d1kxvc_, d1kxvd_
  has additional subdomain(s) that are not in the common domain
Domain for 1ose:
- Domain d1osea2: 1ose A:1-403 [28753]
  Other proteins in same PDB: d1osea1
  complexed with bgc, ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 1pif:
- Domain d1pifa2: 1pif A:1-403 [28752]
  Other proteins in same PDB: d1pifa1
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 1pig:
- Domain d1piga2: 1pig A:1-403 [28751]
  Other proteins in same PDB: d1piga1
  complexed with bgc, ca, cl, hmc
  has additional subdomain(s) that are not in the common domain
Domain for 1ppi:
- Domain d1ppia2: 1ppi A:1-403 [28750]
  Other proteins in same PDB: d1ppia1
  complexed with ca, cl
  has additional subdomain(s) that are not in the common domain
Domain for 1ua3:
- Domain d1ua3a2: 1ua3 A:1-403 [99127]
  Other proteins in same PDB: d1ua3a1
  complexed with bgc, ca, cl, edo
  has additional subdomain(s) that are not in the common domain
Domain for 1wo2:
- Domain d1wo2a2: 1wo2 A:1-403 [121109]
  Other proteins in same PDB: d1wo2a1
  automated match to d1hx0a2
  complexed with ca, cl, edo
  has additional subdomain(s) that are not in the common domain

Yellow mealworm (Tenebrio molitor), larva [TaxId:7067] [51461] (4 PDB entries)
1. Domain for 1clv:
  - Domain d1clva2: 1clv A:1-378 [28761]
    Other proteins in same PDB: d1clva1, d1clvi_
    complexed with ca, cl
    has additional subdomain(s) that are not in the common domain
2. Domain for 1jae:
  - Domain d1jaea2: 1jae A:1-378 [28760]
    Other proteins in same PDB: d1jaea1
    complexed with ca, cl
    has additional subdomain(s) that are not in the common domain
3. Domain for 1tmq:
  - Domain d1tmqa2: 1tmq A:1-378 [28762]
    Other proteins in same PDB: d1tmqa1, d1tmqb_
    complexed with ca, cl
    has additional subdomain(s) that are not in the common domain
4. Domain for 1viw:
  - Domain d1viwa2: 1viw A:1-378 [28763]
    Other proteins in same PDB: d1viwa1, d1viwb_
    complexed with ca, cl
    has additional subdomain(s) that are not in the common domain

More info for Protein Animal alpha-amylase from c.1.8.1: Amylase, catalytic domain

Timeline for Protein Animal alpha-amylase from c.1.8.1: Amylase, catalytic domain:

Protein Animal alpha-amylase from c.1.8.1: Amylase, catalytic domain first appeared (with stable ids) in SCOP 1.55, called Protein Animal alpha-amylase from c.1.8.1: alpha-Amylases, N-terminal domain
Protein Animal alpha-amylase from c.1.8.1: Amylase, catalytic domain appears in SCOPe 2.07