Lineage for Protein: NAD-dependent deacetylase sirtuin-5

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2107255Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2107256Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2107522Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 protein domains)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 2107568Protein NAD-dependent deacetylase sirtuin-5 [142128] (1 species)

Species:

More info for Protein NAD-dependent deacetylase sirtuin-5 from c.31.1.5: Sir2 family of transcriptional regulators

Timeline for Protein NAD-dependent deacetylase sirtuin-5 from c.31.1.5: Sir2 family of transcriptional regulators:

  • Protein NAD-dependent deacetylase sirtuin-5 from c.31.1.5: Sir2 family of transcriptional regulators first appeared in SCOP 1.73
  • Protein NAD-dependent deacetylase sirtuin-5 from c.31.1.5: Sir2 family of transcriptional regulators appears in SCOPe 2.05