![]() | Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
![]() | Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like |
![]() | Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) ![]() binds cofactor molecules in the opposite direction than classical Rossmann fold |
![]() | Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins) silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain |
![]() | Protein NAD-dependent deacetylase sirtuin-5 [142128] (1 species) |
![]() | Human (Homo sapiens) [TaxId:9606] [142129] (5 PDB entries) Uniprot Q9NXA8 36-302 |
![]() | Domain d2b4ya1: 2b4y A:36-302 [127868] complexed with apr, epe, zn |
![]() | Domain d2b4yb_: 2b4y B: [127869] automated match to d2b4ya1 complexed with apr, epe, zn |
![]() | Domain d2b4yc_: 2b4y C: [127870] automated match to d2b4ya1 complexed with apr, epe, zn |
![]() | Domain d2b4yd_: 2b4y D: [127871] automated match to d2b4ya1 complexed with apr, epe, zn |
![]() | Domain d2fzqa_: 2fzq A: [303904] automated match to d2b4ya1 complexed with svr, zn |
![]() | Domain d2fzqb_: 2fzq B: [303905] automated match to d2b4ya1 complexed with svr, zn |
![]() | Domain d2nyra_: 2nyr A: [138827] automated match to d2b4ya1 complexed with svr, zn |
![]() | Domain d2nyrb_: 2nyr B: [138828] automated match to d2b4ya1 complexed with svr, zn |
![]() | Domain d5xhsa_: 5xhs A: [351738] automated match to d6eqsa_ complexed with mcm, phq, sll, zn |
![]() | Domain d6eqsa_: 6eqs A: [340912] Other proteins in same PDB: d6eqsc2, d6eqsd2 automated match to d2b4ya1 complexed with bu2, bv8, dms, edo, zn |
![]() | Domain d6eqsb_: 6eqs B: [340827] Other proteins in same PDB: d6eqsc2, d6eqsd2 automated match to d2b4ya1 complexed with bu2, bv8, dms, edo, zn |
![]() | Domain d6eqsc1: 6eqs C:34-302 [340934] Other proteins in same PDB: d6eqsc2, d6eqsd2 automated match to d2b4ya1 complexed with bu2, bv8, dms, edo, zn |
![]() | Domain d6eqsd1: 6eqs D:34-302 [341047] Other proteins in same PDB: d6eqsc2, d6eqsd2 automated match to d2b4ya1 complexed with bu2, bv8, dms, edo, zn |
Timeline for Protein NAD-dependent deacetylase sirtuin-5 from c.31.1.5: Sir2 family of transcriptional regulators: