![]() | Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
![]() | Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like |
![]() | Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) ![]() binds cofactor molecules in the opposite direction than classical Rossmann fold |
![]() | Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins) silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain |
![]() | Protein NAD-dependent deacetylase sirtuin-5 [142128] (1 species) |
![]() | Species Human (Homo sapiens) [TaxId:9606] [142129] (5 PDB entries) Uniprot Q9NXA8 36-302 |
![]() | Domain d2b4yd_: 2b4y D: [127871] automated match to d2b4ya1 complexed with apr, epe, zn |
PDB Entry: 2b4y (more details), 1.9 Å
SCOPe Domain Sequences for d2b4yd_:
Sequence, based on SEQRES records: (download)
>d2b4yd_ c.31.1.5 (D:) NAD-dependent deacetylase sirtuin-5 {Human (Homo sapiens) [TaxId: 9606]} psssmadfrkffakakhiviisgagvsaesgvptfrgaggywrkwqaqdlatplafahnp srvwefyhyrrevmgskepnaghraiaecetrlgkqgrrvvvitqnidelhrkagtknll eihgslfktrctscgvvaenykspicpalsgkgapepgtqdasipveklprceeagcggl lrphvvwfgenldpaileevdrelahcdlclvvgtssvvypaamfapqvaargvpvaefn tettpatnrfrfhfqgpcgttlpeala
>d2b4yd_ c.31.1.5 (D:) NAD-dependent deacetylase sirtuin-5 {Human (Homo sapiens) [TaxId: 9606]} psssmadfrkffakakhiviisgagvsaesgvptfywrkwqaqdlatplafahnpsrvwe fyhyrrevmgskepnaghraiaecetrlgkqgrrvvvitqnidelhrkagtknlleihgs lfktrctscgvvaenykspicpalsgkgapepgtqdasipveklprceeagcggllrphv vwfgenldpaileevdrelahcdlclvvgtssvvypaamfapqvaargvpvaefntettp atnrfrfhfqgpcgttlpeala
Timeline for d2b4yd_: