Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2107255Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2107256Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2107522Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 protein domains)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 2107568Protein NAD-dependent deacetylase sirtuin-5 [142128] (1 species)
  7. 2107569Species Human (Homo sapiens) [TaxId:9606] [142129] (4 PDB entries)
    Uniprot Q9NXA8 36-302

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 2b4y:
    1. 2107570Domain d2b4ya1: 2b4y A:36-302 [127868]
      complexed with apr, epe, zn
    2. 2107571Domain d2b4yb_: 2b4y B: [127869]
      automated match to d2b4ya1
      complexed with apr, epe, zn
    3. 2107572Domain d2b4yc_: 2b4y C: [127870]
      automated match to d2b4ya1
      complexed with apr, epe, zn
    4. 2107573Domain d2b4yd_: 2b4y D: [127871]
      automated match to d2b4ya1
      complexed with apr, epe, zn
  2. Domain(s) for 2fzq:
    1. 2107576Domain d2fzqa_: 2fzq A: [303904]
      automated match to d2b4ya1
      complexed with svr, zn
    2. 2107577Domain d2fzqb_: 2fzq B: [303905]
      automated match to d2b4ya1
      complexed with svr, zn
  3. Domain(s) for 2nyr:
    1. 2107574Domain d2nyra_: 2nyr A: [138827]
      automated match to d2b4ya1
      complexed with svr, zn
    2. 2107575Domain d2nyrb_: 2nyr B: [138828]
      automated match to d2b4ya1
      complexed with svr, zn
  4. Domain(s) for 6eqs:
    1. 2297526Domain d6eqsb_: 6eqs B: [340827]
      Other proteins in same PDB: d6eqsc2, d6eqsd2
      automated match to d2b4ya1
      complexed with bu2, bv8, dms, edo, zn
    2. 2297611Domain d6eqsa_: 6eqs A: [340912]
      Other proteins in same PDB: d6eqsc2, d6eqsd2
      automated match to d2b4ya1
      complexed with bu2, bv8, dms, edo, zn
    3. 2297633Domain d6eqsc1: 6eqs C:34-302 [340934]
      Other proteins in same PDB: d6eqsc2, d6eqsd2
      automated match to d2b4ya1
      complexed with bu2, bv8, dms, edo, zn
    4. 2297746Domain d6eqsd1: 6eqs D:34-302 [341047]
      Other proteins in same PDB: d6eqsc2, d6eqsd2
      automated match to d2b4ya1
      complexed with bu2, bv8, dms, edo, zn

More info for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 NAD-dependent deacetylase sirtuin-5

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 NAD-dependent deacetylase sirtuin-5: