Class c: Alpha and beta proteins (a/b) [51349] (141 folds) |
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily) 3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like |
Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (6 families) binds cofactor molecules in the opposite direction than classical Rossmann fold |
Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (7 proteins) silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain |
Protein NAD-dependent deacetylase sirtuin-5 [142128] (1 species) |
Human (Homo sapiens) [TaxId:9606] [142129] (2 PDB entries) |
Domain d2b4ya1: 2b4y A:36-302 [127868] complexed with apr, epe, zn |
Domain d2b4yb1: 2b4y B:36-302 [127869] automatically matched to 2B4Y A:36-302 complexed with apr, epe, zn |
Domain d2b4yc1: 2b4y C:36-302 [127870] automatically matched to 2B4Y A:36-302 complexed with apr, epe, zn |
Domain d2b4yd1: 2b4y D:36-302 [127871] automatically matched to 2B4Y A:36-302 complexed with apr, epe, zn |
Domain d2nyra1: 2nyr A:36-302 [138827] automatically matched to 2B4Y A:36-302 complexed with svr, zn |
Domain d2nyrb1: 2nyr B:36-302 [138828] automatically matched to 2B4Y A:36-302 complexed with svr, zn |
Timeline for Protein NAD-dependent deacetylase sirtuin-5 from c.31.1.5: Sir2 family of transcriptional regulators: