Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 694236Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 694237Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (6 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 694413Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (7 proteins)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 694459Protein NAD-dependent deacetylase sirtuin-5 [142128] (1 species)
  7. 694460Species Human (Homo sapiens) [TaxId:9606] [142129] (2 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 2b4y:
    1. 694463Domain d2b4ya1: 2b4y A:36-302 [127868]
      complexed with apr, epe, zn
    2. 694464Domain d2b4yb1: 2b4y B:36-302 [127869]
      automatically matched to 2B4Y A:36-302
      complexed with apr, epe, zn
    3. 694465Domain d2b4yc1: 2b4y C:36-302 [127870]
      automatically matched to 2B4Y A:36-302
      complexed with apr, epe, zn
    4. 694466Domain d2b4yd1: 2b4y D:36-302 [127871]
      automatically matched to 2B4Y A:36-302
      complexed with apr, epe, zn
  2. Domain(s) for 2nyr:
    1. 694461Domain d2nyra1: 2nyr A:36-302 [138827]
      automatically matched to 2B4Y A:36-302
      complexed with svr, zn
    2. 694462Domain d2nyrb1: 2nyr B:36-302 [138828]
      automatically matched to 2B4Y A:36-302
      complexed with svr, zn

More info for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 NAD-dependent deacetylase sirtuin-5

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.31.1.5 NAD-dependent deacetylase sirtuin-5: