PDB entry 4c2m

View 4c2m on RCSB PDB site
Description: Structure of RNA polymerase I at 2.8 A resolution
Class: transcription
Keywords: transcription, ribosome biogenesis
Deposited on 2013-08-19, released 2013-10-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2015-08-19, with a file datestamp of 2015-08-14.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2m1_
  • Chain '2':
    Compound: DNA-directed RNA polymerase I subunit RPA49
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2m2_
  • Chain '3':
    Compound: DNA-directed RNA polymerase I subunit RPA34
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2m3_
  • Chain '4':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'A':
    Compound: DNA-directed RNA polymerase I subunit rpa190
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2ma_
  • Chain 'B':
    Compound: DNA-directed RNA polymerase I subunit rpa135
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mb_
  • Chain 'C':
    Compound: DNA-directed RNA polymerases I and III subunit rpac1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mc1, d4c2mc2
  • Chain 'D':
    Compound: DNA-directed RNA polymerase I subunit rpa14
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2me1, d4c2me2
  • Chain 'F':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mf_
  • Chain 'G':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mg1
  • Chain 'H':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 3
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mh_
  • Chain 'I':
    Compound: DNA-directed RNA polymerase I subunit rpa12
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mi1, d4c2mi2
  • Chain 'J':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 5
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mj_
  • Chain 'K':
    Compound: DNA-directed RNA polymerases I and III subunit rpac2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mk_
  • Chain 'L':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2ml_
  • Chain 'M':
    Compound: DNA-directed RNA polymerase I subunit RPA49
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mm_
  • Chain 'N':
    Compound: DNA-directed RNA polymerase I subunit RPA34
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mn_
  • Chain 'O':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: DNA-directed RNA polymerase I subunit rpa190
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mp_
  • Chain 'Q':
    Compound: DNA-directed RNA polymerase I subunit rpa135
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mq_
  • Chain 'R':
    Compound: DNA-directed RNA polymerases I and III subunit rpac1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mr1, d4c2mr2
  • Chain 'S':
    Compound: DNA-directed RNA polymerase I subunit rpa14
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'T':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mt1, d4c2mt2
  • Chain 'U':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mu_
  • Chain 'V':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mv1
  • Chain 'W':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 3
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mw_
  • Chain 'X':
    Compound: DNA-directed RNA polymerase I subunit rpa12
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mx1, d4c2mx2
  • Chain 'Y':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 5
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2my_
  • Chain 'Z':
    Compound: DNA-directed RNA polymerases I and III subunit rpac2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c2mz_
  • Heterogens: ZN, SO4, HOH

PDB Chain Sequences:

  • Chain '1':
    Sequence, based on SEQRES records: (download) 
    >4c2m1 (1:)
msregfqiptnldaaaagtsqartatlkyicaecssklslsrtdavrckdcghrillkar
tkrlvqfear

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2m1 (1:)
lkyicaecssklslsrtdavrckdcghrillkartkrlvqfear

  • Chain '2':
    Sequence, based on SEQRES records: (download) 
    >4c2m2 (2:)
msvkrsvseieiesvqdqpsvavgsffkgfrapsdttfdlykkkksekdefvlhgenerl
eyegytdsssqasnqyvvglfnpekksiqlykapvlvskvvskssknlrgpkiksksdtr
psalrnalgeafgtkkakkaiadlernridsdkltdsaidivdsvrtaskdlptraqlde
itsndrptplanidatdveqiypiesiipkkelqfirvssilkeadkekklelfpyqnns
kyvakkldsltqpsqmtklqllyylslllgvyenrrvnnktkllerlnsppeilvdgils
rftvikpgqfgrskdrsyfidpqnedkilcyilaiimhldnfiveitplahelnlkpskv
vslfrvlgaivkgatvaqaeafgipkstaasykiatmkvpfklpemtrrgrgprr

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2m2 (2:)
seieiesvqdqpsvavgsffkgfrapsdttfdlykkdefvlhgenerleyegytdsssqa
snqyvvglfnpekksiqlykapvlvskvvskssknlrgpkiks

  • Chain '3':
    Sequence, based on SEQRES records: (download) 
    >4c2m3 (3:)
msklskdyvsdsdsddevisnefsipdgfkkckhlknfplngdnkkkakqqqvwlikfps
nvdisklkslpvdfessttmtidkhdykimddtdiessltqdnlsnmtllvpseskeslk
iastakdnaplqfdkvfsvsetakipaidyskvrvprkdvpkveglklehfatgydaedf
hvaeevkenkkepkkrshhddeeessekkkkkkekrekrekkdkkdkkkkhrd

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2m3 (3:)
ipdgfkkckhlknfplnqqqvwlikfpsnvdisklkslpvsttmtidkhdykimddtdie
ssltqdnlsnmtllvpseskeslkiastakdnaplqfdkvfsvsetakipaidyskvrvp
rkdvpkveglklehfatgydaedfh

  • Chain '4':
    No sequence available.

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4c2mA (A:)
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitlgslnssmytddeaiednedemdgegskqskdisstllne
lkskrseyvdmaiakalsdgrttergsftatvnderkklvhefhkkllsrgkcdncgmfs
pkfrkdgftkifetalnekqitnnrvkgfirqdmikkqkqakkldgsneasandeesfdv
grnpttrpktgstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvl
vvpptrfrlpsklgeevhensqnqllskvlttsllirdlnddlsklqkdkvsledrrvif
srlmnafvtiqndvnafidstkaqgrtsgkvpipgvkqalekkeglfrkhmmgkrvnyaa
rsvispdpnietneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqned
gslvsligmsveqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasm
mghkvrvlpnektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltp
tsgspvrgliqdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptif
kpyplwtgkqiittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgi
ldksqygaskygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegn
kwrtdilktsvdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskv
naitsqvvskcvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvm
vsgktlpsfkpyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylq
rcltkqlegvhvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkky
npsaliehldvesalkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenf
qdklesfldknsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqm
tlntfhfaghgaanvtlgiprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksisk
vllsevidkvivtettgtsntaggnaarsyvihmrffdnneyseeydvskeelqnvisnq
fihlleaaivkeikkqkrttgpdigvavprlqtdvansssnskrleedndeeqshkktkq
avsydepdedeietmreaekssdeegidsdkesdsdsededvdmneqinksiveannnmn
kvqrdrqsaiishhrfitkynfddesgkwcefklelaadtekllmvniveeicrksiirq
iphidrcvhpepengkrvlvtegvnfqamwdqeafidvdgitsndvaavlktygveaarn
tivneinnvfsryaisvsfrhldliadmmtrqgtylafnrqgmetstssfmkmsyettcq
fltkavldnereqldspsarivvgklnnvgtgsfdvlakvpnaa

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mA (A:)
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitlsstllnelkskrseyvdmaiakalsdgrttergsftatv
nderkklvhefhkkllsrgkcdncgmfspkfrkdgftkifetalnekqitnnrvkgfirq
dstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvlvvpptrfrlp
sklgeevhensqnqllskvlttsllirdlnddlsklqkdkvsledrrvifsrlmnafvti
qndvnafidstkaqgrtsgkvpipgvkqalekkeglfrkhmmgkrvnyaarsvispdpni
etneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqnedgslvsligms
veqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasmmghkvrvlpn
ektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltptsgspvrgli
qdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptifkpyplwtgkq
iittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgildksqygask
ygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegnkwrtdilkts
vdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskvnaitsqvvsk
cvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvmvsgktlpsfk
pyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylqrcltkqlegv
hvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkkynpsaliehld
vesalkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenfqdklesfldk
nsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqmtlntfanvtl
giprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksiskvllsevidkvivtetta
arsyvihmrffdnneyseeydvskeelqnvisnqfihlleaaivkeikkqkrtpdigvav
pnskrleedndeeqshkktkqavsydepdedeietmnkvqrdrqsaiishhrfitkynfd
desgkwcefklelaadtekllmvniveeicrksiirqiphidrcvhpepengkrvlvteg
vnfqamwdqeafidvdgitsndvaavlktygveaarntivneinnvfsryaisvsfrhld
liadmmtrqgtylafnrqgmetstssfmkmsyettcqfltkavldnereqldspsarivv
gklnnvgtgsfdvlakvpnaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4c2mB (B:)
mskvikppgqartadfrtleresrfinppkdksafpllqeavqphigsfnaltegpdggl
lnlgvkdigekvifdgkplnsedeisnsgylgnklsvsveqvsiakpmsndgvssaverk
vypsesrqrltsyrgklllklkwsvnngeenlfevrdcgglpvmlqsnrchlnkmspyel
vqhkeesdeiggyfivngieklirmlivqrrnhpmaiirpsfanrgasyshygiqirsvr
pdqtsqtnvlhylndgqvtfrfswrkneylvpvvmilkalchtsdreifdgiigndvkds
fltdrlelllrgfkkryphlqnrtqvlqylgdkfrvvfqaspdqsdlevgqevldrivlv
hlgkdgsqdkfrmllfmirklyslvagecspdnpdatqhqevllggflygmilkekidey
lqniiaqvrmdinrgmainfkdkrymsrvlmrvnenigskmqyflstgnlvsqsgldlqq
vsgytvvaekinfyrfishfrmvhrgsffaqlktttvrkllpeswgflcpvhtpdgspcg
llnhfahkcristqqsdvsripsilyslgvapashtfaagpslccvqidgkiigwvsheq
gkiiadtlrywkvegktpglpidleigyvppstrgqypglylfgghsrmlrpvrylpldk
edivgpfeqvymniavtpqeiqnnvhthveftptnilsilanltpfsdfnqsprnmyqcq
mgkqtmgtpgvalchrsdnklyrlqtgqtpivkanlyddygmdnfpngfnavvavisytg
ydmddamiinksadergfgygtmyktekvdlalnrnrgdpitqhfgfgndewpkewlekl
dedglpyigtyveegdpicayfddtlnktkiktyhssepayieevnligdesnkfqelqt
vsikyrirrtpqigdkfssrhgqkgvcsrkwptidmpfsetgiqpdiiinphafpsrmti
gmfveslagkagalhgiaqdstpwifneddtpadyfgeqlakagynyhgnepmysgatge
elradiyvgvvyyqrlrhmvndkfqvrstgpvnsltmqpvkgrkrhggirvgemerdali
ghgtsfllqdrllnssdytqasvcrecgsilttqqsvprigsistvccrrcsmrfedakk
lltksedgekifiddsqiwedgqgnkfvggnetttvaipfvlkyldselsamgirlrynv
epk

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mB (B:)
pgqartadfrtleresrfinppkdksafpllqeavqphigsfnaltegpdggllnlgvkd
igekvifdgkplnsnsgylgnklsvsveqvsiakpmsndgvssaverkvypsesrqrlts
yrgklllklkwsvnngeenlfevrdcgglpvmlqsnrchlnkmspyelvqhkeesdeigg
yfivngieklirmlivqrrnhpmaiirpsfanrgasyshygiqirsvrpdqtsqtnvlhy
lndgqvtfrfswrkneylvpvvmilkalchtsdreifdgiigndvkdsfltdrlelllrg
fkkryphlqnrtqvlqylgdkfrvvfqaspdqsdlevgqevldrivlvhlgkdgsqdkfr
mllfmirklyslvagecspdnpdatqhqevllggflygmilkekideylqniiaqvrmdi
nrgmainfkdkrymsrvlmrvnenigskmqyflstgnlvsqsgldlqqvsgytvvaekin
fyrfishfrmvhrgsffaqlktttvrkllpeswgflcpvhtpdgspcgllnhfahkcris
tqqsdvsripsilyslgvapashtfaagpslccvqidgkiigwvsheqgkiiadtlrywk
vegktpglpidleigyvppstrgqypglylfgghsrmlrpvrylpldkedivgpfeqvym
niavtpqeiqnnvhthveftptnilsilanltpfsdfnqsprnmyqcqmgkqtmgtpgva
lchrsdnklyrlqtgqtpivkanlyddygmdnfpngfnavvavisytgydmddamiinks
adergfgygtmyktekvdlalnrnrgdpitqhfgfgndewpkewlekldedglpyigtyv
eegdpicayfddtlnktkiktyhssepayieevnligdesnkfqelqtvsikyrirrtpq
igdkfssrhgqkgvcsrkwptidmpfsetgiqpdiiinphafpsrmtigmfveslagkag
alhgiaqdstpwifneddtpadyfgeqlakagynyhgnepmysgatgeelradiyvgvvy
yqrlrhmvndkfqvrstgpvnsltmqpvkgrkrhggirvgemerdalighgtsfllqdrl
lnssdytqasvcrecgsilttqqsvprigsistvccrrcsmrfedakklifiddsqiwed
gqgnkfvggnetttvaipfvlkyldselsamgirlrynvepk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4c2mC (C:)
msnivgieynrvtnttstdfpgfskdaenewnvekfkkdfevnissldareanfdlinid
tsianafrrimisevpsvaaeyvyffnntsviqdevlahriglvplkvdpdmltwvdsnl
pddekftdentivlslnvkctrnpdapkgstdpkelynnahvyardlkfepqgrqsttfa
dcpvvpadpdillaklrpgqeislkahcilgiggdhakfspvstasyrllpqinilqpik
gesarrfqkcfppgvigidegsdeayvkdarkdtvsrevlryeefadkvklgrvrnhfif
nvesagamtpeeiffksvrilknkaeylkncpitq

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mC (C:)
wnvekfkkdfevnissldareanfdlinidtsianafrrimisevpsvaaeyvyffnnts
viqdevlahriglvplkvdpdmltwvdsnlpddekftdentivlslnvkctrnpdapkgs
tdpkelynnahvyardlkfepqgrqsttfadcpvvpadpdillaklrpgqeislkahcil
giggdhakfspvstasyrllpqinilqpikgesarrfqkcfppgvigidegsdeayvkda
rkdtvsrevlryeefadkvklgrvrnhfifnvesagamtpeeiffksvrilknkaeylkn
cpitq

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >4c2mE (E:)
mdqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsf
qanpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsa
mklvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqr
adpvalylglkrgevvkiirksetsgryasyricm

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mE (E:)
enernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsfqan
pteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsamkl
vpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqradp
valylglkrgevvkiirksetsgryasyricm

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >4c2mF (F:)
msdyeeafndgnenfedfdvehfsdeetyeekpqfkdgettdangktivtggngpedfqq
heqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlegetdplri
amkelaekkiplvirrylpdgsfedwsveelivdl

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mF (F:)
pedfqqheqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlege
tdplriamkelaekkiplvirrylpdgsfedwsveelivd

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >4c2mG (G:)
msqvkranenretarfikkhkkqvtnpidekngtsncivrvpialyvslapmylenplqg
vmkqhlnplvmkynnkvggvvlgyeglkildadplskedtseklikitpdtpfgftwchv
nlyvwqpqvgdvlegyifiqsashigllihdafnasikknnipvdwtfvhndveedadvi
ntdenngnnnnednkdsnggsnslgkfsfgnrslghwvdsngepidgklrftvrnvhttg
rvvsvdgtlisdadeegngynssrsqaeslpivsnkkivfddevsienkeshkeldlpev
kedngseivyeentsesndgessdsd

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mG (G:)
arfikkhkkqvtnpidekngtsncivrvpialyvslapmylenplqgvmkqhlnplvmky
nnkvggvvlgyeglkildadplskedtseklikitpdtpfgftwchvnlyvwqpqvgdvl
egyifiqsashigllihdafnasikknnipvdwtfvhghwvdsngepidgklrftvrnvh
ttgrvvsvdgtli

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >4c2mH (H:)
msntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtia
sslnledtpandssatrswrppqagdrsladdydyvmygtaykfeevskdliavyysfgg
llmrlegnyrnlnnlkqenayllirr

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mH (H:)
ntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtiass
lnswrppqagdrsladdydyvmygtaykfeevskdliavyysfggllmrlegnyrnlnnl
kqenayllirr

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >4c2mI (I:)
msvvgslifcldcgdllenpnavlgsnvecsqckaiypksqfsnlkvvtttaddafpssl
rakksvvktslkknelkdgatikekcpqcgneemnyhtlqlrsadegatvfytctscgyk
frtnn

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mI (I:)
svvgslifcldcgdllenpnavlgsnvecsqckaiypksqfsnlkvvtttaddafpsslr
akksvvktslkknelkdgatikekcpqcgneemnyhtlqlrsadegatvfytctscgykf
rtnn

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >4c2mJ (J:)
mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
lrynplekrd

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mJ (J:)
mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
lrynplekr

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >4c2mK (K:)
mtedieqkktatevtpqepkhiqeeeeqdvdmtgdeeqeeepdrekiklltqatsedgts
asfqiveedhtlgnalryvimknpdvefcgysiphpsenllniriqtygettavdalqkg
lkdlmdlcdvveskftekiksm

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mK (K:)
pdrekiklltqatsedgtsasfqiveedhtlgnalryvimknpdvefcgysiphpsenll
niriqtygettavdalqkglkdlmdlcdvveskftekiksm

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >4c2mL (L:)
msregfqiptnldaaaagtsqartatlkyicaecssklslsrtdavrckdcghrillkar
tkrlvqfear

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mL (L:)
lkyicaecssklslsrtdavrckdcghrillkartkrlvqfear

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >4c2mM (M:)
msvkrsvseieiesvqdqpsvavgsffkgfrapsdttfdlykkkksekdefvlhgenerl
eyegytdsssqasnqyvvglfnpekksiqlykapvlvskvvskssknlrgpkiksksdtr
psalrnalgeafgtkkakkaiadlernridsdkltdsaidivdsvrtaskdlptraqlde
itsndrptplanidatdveqiypiesiipkkelqfirvssilkeadkekklelfpyqnns
kyvakkldsltqpsqmtklqllyylslllgvyenrrvnnktkllerlnsppeilvdgils
rftvikpgqfgrskdrsyfidpqnedkilcyilaiimhldnfiveitplahelnlkpskv
vslfrvlgaivkgatvaqaeafgipkstaasykiatmkvpfklpemtrrgrgprr

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mM (M:)
seieiesvqdqpsvavgsffkgfrapsdttfdlykkkksekdefvlhgenerleyegytd
sssqasnqyvvglfnpekksiqlykapvlvskvvskssknlrgpkiks

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >4c2mN (N:)
msklskdyvsdsdsddevisnefsipdgfkkckhlknfplngdnkkkakqqqvwlikfps
nvdisklkslpvdfessttmtidkhdykimddtdiessltqdnlsnmtllvpseskeslk
iastakdnaplqfdkvfsvsetakipaidyskvrvprkdvpkveglklehfatgydaedf
hvaeevkenkkepkkrshhddeeessekkkkkkekrekrekkdkkdkkkkhrd

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mN (N:)
sipdgfkkckhlknfplnkqqqvwlikfpsnvdisklkslpvttmtidkhdykimddtdi
essltqdnlsnmtllvpseskeslkiastakdnaplqfdkvfsvsetakipaidyskvrv
prkdvpkveglklehfatgydaedf

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >4c2mP (P:)
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitlgslnssmytddeaiednedemdgegskqskdisstllne
lkskrseyvdmaiakalsdgrttergsftatvnderkklvhefhkkllsrgkcdncgmfs
pkfrkdgftkifetalnekqitnnrvkgfirqdmikkqkqakkldgsneasandeesfdv
grnpttrpktgstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvl
vvpptrfrlpsklgeevhensqnqllskvlttsllirdlnddlsklqkdkvsledrrvif
srlmnafvtiqndvnafidstkaqgrtsgkvpipgvkqalekkeglfrkhmmgkrvnyaa
rsvispdpnietneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqned
gslvsligmsveqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasm
mghkvrvlpnektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltp
tsgspvrgliqdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptif
kpyplwtgkqiittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgi
ldksqygaskygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegn
kwrtdilktsvdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskv
naitsqvvskcvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvm
vsgktlpsfkpyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylq
rcltkqlegvhvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkky
npsaliehldvesalkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenf
qdklesfldknsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqm
tlntfhfaghgaanvtlgiprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksisk
vllsevidkvivtettgtsntaggnaarsyvihmrffdnneyseeydvskeelqnvisnq
fihlleaaivkeikkqkrttgpdigvavprlqtdvansssnskrleedndeeqshkktkq
avsydepdedeietmreaekssdeegidsdkesdsdsededvdmneqinksiveannnmn
kvqrdrqsaiishhrfitkynfddesgkwcefklelaadtekllmvniveeicrksiirq
iphidrcvhpepengkrvlvtegvnfqamwdqeafidvdgitsndvaavlktygveaarn
tivneinnvfsryaisvsfrhldliadmmtrqgtylafnrqgmetstssfmkmsyettcq
fltkavldnereqldspsarivvgklnnvgtgsfdvlakvpnaa

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mP (P:)
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitlsstllnelkskrseyvdmaiakalsdgrttergsftatv
nderkklvhefhkkllsrgkcdncgmfspkfrkdgftkifetalnekqitnnrvkgfirq
dstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvlvvpptrfrlp
sklgeevhensqnqllskvlttsllirdlnddlsklqkdkvsledrrvifsrlmnafvti
qndvnafidstkaqgrtsgkvpipgvkqalekkeglfrkhmmgkrvnyaarsvispdpni
etneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqnedgslvsligms
veqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasmmghkvrvlpn
ektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltptsgspvrgli
qdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptifkpyplwtgkq
iittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgildksqygask
ygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegnkwrtdilkts
vdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskvnaitsqvvsk
cvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvmvsgktlpsfk
pyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylqrcltkqlegv
hvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkkynpsaliehld
vesalkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenfqdklesfldk
nsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqmtlntfnvtlg
iprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksiskvllsevidkvivtettaa
rsyvihmrffdnneyseeydvskeelqnvisnqfihlleaaivkeikkqkdigvavprns
krleedndeeqshkktkqavsydepdedeietmnkvqrdrqsaiishhrfitkynfddes
gkwcefklelaadtekllmvniveeicrksiirqiphidrcvhpepengkrvlvtegvnf
qamwdqeafidvdgitsndvaavlktygveaarntivneinnvfsryaisvsfrhldlia
dmmtrqgtylafnrqgmetstssfmkmsyettcqfltkavldnereqldspsarivvgkl
nnvgtgsfdvlakvpnaa

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >4c2mQ (Q:)
mskvikppgqartadfrtleresrfinppkdksafpllqeavqphigsfnaltegpdggl
lnlgvkdigekvifdgkplnsedeisnsgylgnklsvsveqvsiakpmsndgvssaverk
vypsesrqrltsyrgklllklkwsvnngeenlfevrdcgglpvmlqsnrchlnkmspyel
vqhkeesdeiggyfivngieklirmlivqrrnhpmaiirpsfanrgasyshygiqirsvr
pdqtsqtnvlhylndgqvtfrfswrkneylvpvvmilkalchtsdreifdgiigndvkds
fltdrlelllrgfkkryphlqnrtqvlqylgdkfrvvfqaspdqsdlevgqevldrivlv
hlgkdgsqdkfrmllfmirklyslvagecspdnpdatqhqevllggflygmilkekidey
lqniiaqvrmdinrgmainfkdkrymsrvlmrvnenigskmqyflstgnlvsqsgldlqq
vsgytvvaekinfyrfishfrmvhrgsffaqlktttvrkllpeswgflcpvhtpdgspcg
llnhfahkcristqqsdvsripsilyslgvapashtfaagpslccvqidgkiigwvsheq
gkiiadtlrywkvegktpglpidleigyvppstrgqypglylfgghsrmlrpvrylpldk
edivgpfeqvymniavtpqeiqnnvhthveftptnilsilanltpfsdfnqsprnmyqcq
mgkqtmgtpgvalchrsdnklyrlqtgqtpivkanlyddygmdnfpngfnavvavisytg
ydmddamiinksadergfgygtmyktekvdlalnrnrgdpitqhfgfgndewpkewlekl
dedglpyigtyveegdpicayfddtlnktkiktyhssepayieevnligdesnkfqelqt
vsikyrirrtpqigdkfssrhgqkgvcsrkwptidmpfsetgiqpdiiinphafpsrmti
gmfveslagkagalhgiaqdstpwifneddtpadyfgeqlakagynyhgnepmysgatge
elradiyvgvvyyqrlrhmvndkfqvrstgpvnsltmqpvkgrkrhggirvgemerdali
ghgtsfllqdrllnssdytqasvcrecgsilttqqsvprigsistvccrrcsmrfedakk
lltksedgekifiddsqiwedgqgnkfvggnetttvaipfvlkyldselsamgirlrynv
epk

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mQ (Q:)
pgqartadfrtleresrfinppkdksafpllqeavqphigsfnaltegpdggllnlgvkd
igekvifdgkpylgnklsvsveqvsiakpmsndverkvypsesrqrltsyrgklllklkw
svnngeenlfevrdcgglpvmlqsnrchlnkmspyelvqhkeesdeiggyfivngiekli
rmlivqrrnhpmaiirpsfanrgasyshygiqirsvrpdqtsqtnvlhylndgqvtfrfs
wrkneylvpvvmilkalchtsdreifdgiigndvkdsfltdrlelllrgfkkryphlqnr
tqvlqylgdkfrvvfqaspdqsdlevgqevldrivlvhlgkdgsqdkfrmllfmirklys
lvagecspdnpdatqhqevllggflygmilkekideylqniiaqvrmdinrgmainfkdk
rymsrvlmrvnenigskmqyflstgnlvsqsgldlqqvsgytvvaekinfyrfishfrmv
hrgsffaqlktttvrkllpeswgflcpvhtpdgspcgllnhfahkcristqqsdvsrips
ilyslgvapashtfaagpslccvqidgkiigwvsheqgkiiadtlrywkvegktpglpid
leigyvppstrgqypglylfgghsrmlrpvrylpldkedivgpfeqvymniavtpqeiqn
nvhthveftptnilsilanltpfsdfnqsprnmyqcqmgkqtmgtpgvalchrsdnklyr
lqtgqtpivkanlyddygmdnfpngfnavvavisytgydmddamiinksadergfgygtm
yktekvdlalnrnpitqhfgfgndewpkewlekldedglpyigtyveegdpicayfddtl
nktkiktyhssepayieevnligdeqelqtvsikyrirrtpqigdkfssrhgqkgvcsrk
wptidmpfsetgiqpdiiinphafpsrmtigmfveslagkagalhgiaqdstpwifnedd
tpadyfgeqlakagynyhgnepmysgatgeelradiyvgvvyyqrlrhmvndkfqvrstg
pvnsltmqpvkgrkrhggirvgemerdalighgtsfllqdrllnssdytqasvcrecgsi
lttqqsvprigsistvccrrcsmrfedakklifiddsqiwedgqgnkfvggnetttvaip
fvlkyldselsamgirlrynvepk

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >4c2mR (R:)
msnivgieynrvtnttstdfpgfskdaenewnvekfkkdfevnissldareanfdlinid
tsianafrrimisevpsvaaeyvyffnntsviqdevlahriglvplkvdpdmltwvdsnl
pddekftdentivlslnvkctrnpdapkgstdpkelynnahvyardlkfepqgrqsttfa
dcpvvpadpdillaklrpgqeislkahcilgiggdhakfspvstasyrllpqinilqpik
gesarrfqkcfppgvigidegsdeayvkdarkdtvsrevlryeefadkvklgrvrnhfif
nvesagamtpeeiffksvrilknkaeylkncpitq

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mR (R:)
wnvekfkkdfevnissldareanfdlinidtsianafrrimisevpsvaaeyvyffnnts
viqdevlahriglvplkvdpdmltwvdsnlpddekftdentivlslnvkctrnpdapkgs
tdpkelynnahvyardlkfepqgrqsttfadcpvvpadpdillaklrpgqeislkahcil
giggdhakfspvstasyrllpqinilqpikgesarrfqkcfppgvigidegsdeayvkda
rkdtvsrevlryeefadkvklgrvrnhfifnvesagamtpeeiffksvrilknkaeylkn
cpitq

  • Chain 'S':
    No sequence available.

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >4c2mT (T:)
mdqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsf
qanpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsa
mklvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqr
adpvalylglkrgevvkiirksetsgryasyricm

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mT (T:)
enernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsfqan
pteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsamkl
vpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqradp
valylglkrgevvkiirksetsgryasyricm

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >4c2mU (U:)
msdyeeafndgnenfedfdvehfsdeetyeekpqfkdgettdangktivtggngpedfqq
heqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlegetdplri
amkelaekkiplvirrylpdgsfedwsveelivdl

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mU (U:)
pedfqqheqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlege
tdplriamkelaekkiplvirrylpdgsfedwsveelivd

  • Chain 'V':
    Sequence, based on SEQRES records: (download) 
    >4c2mV (V:)
msqvkranenretarfikkhkkqvtnpidekngtsncivrvpialyvslapmylenplqg
vmkqhlnplvmkynnkvggvvlgyeglkildadplskedtseklikitpdtpfgftwchv
nlyvwqpqvgdvlegyifiqsashigllihdafnasikknnipvdwtfvhndveedadvi
ntdenngnnnnednkdsnggsnslgkfsfgnrslghwvdsngepidgklrftvrnvhttg
rvvsvdgtlisdadeegngynssrsqaeslpivsnkkivfddevsienkeshkeldlpev
kedngseivyeentsesndgessdsd

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mV (V:)
arfikkhkkqvtnpidngtsncivrvpialyvslapmylenplqgvmkqhlnplvmkynn
kvggvvlgyeglkildadplskedtseklikitpdtpfgftwchvnlyvwqpqvgdvleg
yifiqsashigllihdafnasikknnipvdwtfvhndveedghwvdsngepidgklrftv
rnvhttgrvvsvdgtli

  • Chain 'W':
    Sequence, based on SEQRES records: (download) 
    >4c2mW (W:)
msntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtia
sslnledtpandssatrswrppqagdrsladdydyvmygtaykfeevskdliavyysfgg
llmrlegnyrnlnnlkqenayllirr

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mW (W:)
ntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtiass
lnswrppqagdrsladdydyvmygtaykfeevskdliavyysfggllmrlegnyrnlnnl
kqenayllirr

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >4c2mX (X:)
msvvgslifcldcgdllenpnavlgsnvecsqckaiypksqfsnlkvvtttaddafpssl
rakksvvktslkknelkdgatikekcpqcgneemnyhtlqlrsadegatvfytctscgyk
frtnn

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mX (X:)
svvgslifcldcgdllenpnavlgsnvecsqckaiypksqfsnlkvvtttaddafpsslr
akksvvktslkdgatikekcpqcgneemnyhtlqlrsadegatvfytctscgykfrtnn

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >4c2mY (Y:)
mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
lrynplekrd

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mY (Y:)
mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
lrynplekr

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >4c2mZ (Z:)
mtedieqkktatevtpqepkhiqeeeeqdvdmtgdeeqeeepdrekiklltqatsedgts
asfqiveedhtlgnalryvimknpdvefcgysiphpsenllniriqtygettavdalqkg
lkdlmdlcdvveskftekiksm

    Sequence, based on observed residues (ATOM records): (download) 
    >4c2mZ (Z:)
drekiklltqatsedgtsasfqiveedhtlgnalryvimknpdvefcgysiphpsenlln
iriqtygettavdalqkglkdlmdlcdvveskftekiksm