SCOPe 2.06: Species: Human (Homo sapiens) [TaxId: 9606]

Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.06
Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
shares functional and structural similarities with the ATP-grasp fold and PIPK
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
members organized in the groups and subfamiles specified by the comments
Protein Tyrosine-protein kinase SYK [118131] (1 species)
PTK group; SYK/ZAP-70 subfamily; non-membrane spanning protein tyrosine kinase
Species Human (Homo sapiens) [TaxId:9606] [118132] (60 PDB entries)
Uniprot P43405 363-635 # structure of the SH2 domain tandem region (9-265) is also known (55576)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

Domain(s) for 1xba:
- Domain d1xbaa1: 1xba A:363-635 [115076]
  Other proteins in same PDB: d1xbaa2
  Structural genomics target
Domain(s) for 1xbb:
- Domain d1xbba1: 1xbb A:363-637 [115077]
  Other proteins in same PDB: d1xbba2
  Structural genomics target
  complexed with sti
Domain(s) for 1xbc:
- Domain d1xbca1: 1xbc A:363-635 [115078]
  Other proteins in same PDB: d1xbca2
  Structural genomics target
  complexed with stu
Domain(s) for 3emg:
- Domain d3emga_: 3emg A: [175086]
  automated match to d1xbaa_
  complexed with 685
Domain(s) for 3fqe:
- Domain d3fqea1: 3fqe A:363-635 [175975]
  Other proteins in same PDB: d3fqea2
  automated match to d1xbba_
  complexed with p5c
Domain(s) for 3fqh:
1. Domain d3fqha_: 3fqh A: [175977]
  automated match to d1xbba_
  complexed with 057
2. Domain d3fqhb_: 3fqh B: [175978]
  automated match to d1xbba_
  complexed with 057
Domain(s) for 3fqs:
- Domain d3fqsa1: 3fqs A:363-635 [175985]
  Other proteins in same PDB: d3fqsa2
  automated match to d1xbba_
  complexed with 585
Domain(s) for 3srv:
1. Domain d3srva_: 3srv A: [185500]
  automated match to d1xbaa_
  complexed with gol, s19
2. Domain d3srvb_: 3srv B: [185501]
  automated match to d1xbaa_
  complexed with gol, s19
Domain(s) for 3tub:
- Domain d3tuba_: 3tub A: [217031]
  automated match to d1u59a_
  complexed with fpu
Domain(s) for 3tuc:
- Domain d3tuca_: 3tuc A: [217032]
  automated match to d1u59a_
  complexed with fpw
Domain(s) for 3tud:
- Domain d3tuda1: 3tud A:363-635 [217033]
  Other proteins in same PDB: d3tuda2
  automated match to d1u59a_
  complexed with fpx
Domain(s) for 3vf8:
- Domain d3vf8a_: 3vf8 A: [217795]
  automated match to d1u59a_
  complexed with 0je
Domain(s) for 3vf9:
- Domain d3vf9a_: 3vf9 A: [217796]
  automated match to d1u59a_
  complexed with 477
Domain(s) for 4dfl:
- Domain d4dfla1: 4dfl A:363-635 [195550]
  Other proteins in same PDB: d4dfla2
  automated match to d1xbaa_
  complexed with 0k0, edo, so4
Domain(s) for 4dfn:
- Domain d4dfna1: 4dfn A:363-635 [219739]
  Other proteins in same PDB: d4dfna2
  automated match to d4dfla_
  complexed with 0k1
Domain(s) for 4f4p:
- Domain d4f4pa1: 4f4p A:365-635 [194235]
  Other proteins in same PDB: d4f4pa2
  automated match to d1xbba_
  complexed with 0sb, so4
Domain(s) for 4fl1:
- Domain d4fl1a_: 4fl1 A: [221264]
  automated match to d1xbba_
  complexed with anp, mg
Domain(s) for 4fyn:
- Domain d4fyna1: 4fyn A:363-635 [221596]
  Other proteins in same PDB: d4fyna2
  automated match to d1xbba_
  complexed with 0ve
Domain(s) for 4fyo:
- Domain d4fyoa1: 4fyo A:363-635 [193271]
  Other proteins in same PDB: d4fyoa2
  automated match to d1xbba_
  complexed with 0vf
Domain(s) for 4fz6:
- Domain d4fz6a1: 4fz6 A:363-635 [221629]
  Other proteins in same PDB: d4fz6a2
  automated match to d1xbba_
  complexed with 0vg
Domain(s) for 4fz7:
- Domain d4fz7a1: 4fz7 A:363-635 [221630]
  Other proteins in same PDB: d4fz7a2
  automated match to d1xbba_
  complexed with 0vh
Domain(s) for 4gfg:
- Domain d4gfga1: 4gfg A:363-635 [221885]
  Other proteins in same PDB: d4gfga2
  automated match to d1xbba_
  complexed with 0xf
Domain(s) for 4i0r:
- Domain d4i0ra1: 4i0r A:363-635 [228655]
  Other proteins in same PDB: d4i0ra2
  automated match to d1xbba_
  complexed with 1b4
Domain(s) for 4i0s:
- Domain d4i0sa1: 4i0s A:363-635 [228656]
  Other proteins in same PDB: d4i0sa2
  automated match to d1xbba_
  complexed with 1b5
Domain(s) for 4i0t:
- Domain d4i0ta1: 4i0t A:363-635 [228654]
  Other proteins in same PDB: d4i0ta2
  automated match to d1xbba_
  complexed with 1b6
Domain(s) for 4puz:
1. Domain d4puza_: 4puz A: [257562]
  automated match to d1xbba_
  complexed with cg9
2. Domain d4puzb_: 4puz B: [257563]
  automated match to d1xbba_
  complexed with cg9
Domain(s) for 4pv0:
- Domain d4pv0a1: 4pv0 A:363-635 [257561]
  Other proteins in same PDB: d4pv0a2
  automated match to d4fyoa_
  complexed with cg4, cl
Domain(s) for 4rss:
- Domain d4rssa_: 4rss A: [278423]
  automated match to d3tuca_
  complexed with 4mg
Domain(s) for 4rx7:
- Domain d4rx7a1: 4rx7 A:363-635 [270468]
  Other proteins in same PDB: d4rx7a2
  automated match to d3tuca_
  complexed with 3yv, fmt, gol
Domain(s) for 4rx8:
- Domain d4rx8a1: 4rx8 A:364-635 [270474]
  Other proteins in same PDB: d4rx8a2
  automated match to d3tuca_
  complexed with 3yx, gol
Domain(s) for 4rx9:
- Domain d4rx9a1: 4rx9 A:363-635 [270482]
  Other proteins in same PDB: d4rx9a2
  automated match to d3tuca_
  complexed with 3yt, gol
Domain(s) for 4wnm:
- Domain d4wnma1: 4wnm A:363-635 [311578]
  Other proteins in same PDB: d4wnma2
  automated match to d3tuca_
  complexed with 3rt, so4
Domain(s) for 4xg2:
- Domain d4xg2a1: 4xg2 A:364-635 [280193]
  Other proteins in same PDB: d4xg2a2
  automated match to d3tuca_
Domain(s) for 4xg3:
1. Domain d4xg3a_: 4xg3 A: [280185]
  automated match to d3tuca_
  complexed with x3g
2. Domain d4xg3b_: 4xg3 B: [280189]
  automated match to d3tuca_
  complexed with x3g
Domain(s) for 4xg4:
- Domain d4xg4a_: 4xg4 A: [280182]
  automated match to d3tuca_
  complexed with x4g
Domain(s) for 4xg5:
1. Domain d4xg5a_: 4xg5 A: [280190]
  automated match to d3tuca_
  complexed with x5g
2. Domain d4xg5b_: 4xg5 B: [280192]
  automated match to d3tuca_
  complexed with x5g
Domain(s) for 4xg6:
- Domain d4xg6a1: 4xg6 A:363-635 [280186]
  Other proteins in same PDB: d4xg6a2
  automated match to d3tuca_
  complexed with x6g
Domain(s) for 4xg7:
- Domain d4xg7a1: 4xg7 A:364-635 [280188]
  Other proteins in same PDB: d4xg7a2
  automated match to d3tuca_
  complexed with x7g
Domain(s) for 4xg8:
1. Domain d4xg8a_: 4xg8 A: [280183]
  automated match to d3tuca_
  complexed with x8g
2. Domain d4xg8c_: 4xg8 C: [280187]
  automated match to d3tuca_
  complexed with x8g
Domain(s) for 4xg9:
1. Domain d4xg9a_: 4xg9 A: [280191]
  automated match to d3tuca_
  complexed with x9g
2. Domain d4xg9b_: 4xg9 B: [280184]
  automated match to d3tuca_
  complexed with x9g
Domain(s) for 4yjo:
- Domain d4yjoa_: 4yjo A: [277696]
  automated match to d3tuca_
  complexed with 4df, gol
Domain(s) for 4yjp:
- Domain d4yjpa_: 4yjp A: [277685]
  automated match to d3tuca_
  complexed with 4dl, dms
Domain(s) for 4yjq:
- Domain d4yjqa_: 4yjq A: [277688]
  automated match to d3tuca_
  complexed with 4dk
Domain(s) for 4yjr:
- Domain d4yjra_: 4yjr A: [277689]
  automated match to d3tuca_
  complexed with 4dj
Domain(s) for 4yjs:
- Domain d4yjsa_: 4yjs A: [277687]
  automated match to d3tuca_
  complexed with 4dn
Domain(s) for 4yjt:
- Domain d4yjta_: 4yjt A: [277684]
  automated match to d3tuca_
  complexed with 4dq, gol
Domain(s) for 4yju:
- Domain d4yjua_: 4yju A: [277686]
  automated match to d3tuca_
  complexed with 4do
Domain(s) for 4yjv:
- Domain d4yjva_: 4yjv A: [278232]
  automated match to d3tuca_
  complexed with 4dt
Domain(s) for 5c26:
- Domain d5c26a1: 5c26 A:363-635 [277851]
  Other proteins in same PDB: d5c26a2
  automated match to d3tuca_
  complexed with 50h
Domain(s) for 5c27:
- Domain d5c27a1: 5c27 A:363-635 [277850]
  Other proteins in same PDB: d5c27a2
  automated match to d3tuca_
  complexed with 50j, gol
Domain(s) for 5cxh:
- Domain d5cxha1: 5cxh A:363-635 [277113]
  Other proteins in same PDB: d5cxha2
  automated match to d3tuca_
  complexed with 55m
Domain(s) for 5cxz:
- Domain d5cxza1: 5cxz A:363-635 [276972]
  Other proteins in same PDB: d5cxza2
  automated match to d3tuca_
  complexed with 55u, cl, gol
Domain(s) for 5cy3:
- Domain d5cy3a1: 5cy3 A:360-635 [277181]
  Other proteins in same PDB: d5cy3a2
  automated match to d3tuca_
  complexed with 55y
Domain(s) for 5ghv:
1. Domain d5ghva_: 5ghv A: [319342]
  automated match to d3tuca_
  complexed with x5g
2. Domain d5ghvb_: 5ghv B: [319441]
  automated match to d3tuca_
  complexed with x5g
Domain(s) for 5lma:
- Domain d5lmaa_: 5lma A: [322851]
  automated match to d3tuca_
  complexed with 6zg, dms, gol
Domain(s) for 5lmb:
1. Domain d5lmba_: 5lmb A: [322857]
  automated match to d3tuca_
  complexed with 6zf, gol
2. Domain d5lmbb_: 5lmb B: [322835]
  automated match to d3tuca_
  complexed with 6zf, gol
Domain(s) for 5t68:
1. Domain d5t68a1: 5t68 A:363-635 [324581]
  Other proteins in same PDB: d5t68a2
  automated match to d3tuca_
  complexed with 77v
2. Domain d5t68b_: 5t68 B: [324571]
  Other proteins in same PDB: d5t68a2
  automated match to d3tuca_
  complexed with 77v
Domain(s) for 5tiu:
- Domain d5tiua1: 5tiu A:363-635 [328195]
  Other proteins in same PDB: d5tiua2
  automated match to d3tuca_
  complexed with 7cu
Domain(s) for 5tr6:
- Domain d5tr6a1: 5tr6 A:362-635 [326837]
  Other proteins in same PDB: d5tr6a2
  automated match to d3tuca_
  complexed with 7kg, edo
Domain(s) for 5tt7:
- Domain d5tt7a1: 5tt7 A:358-635 [326791]
  Other proteins in same PDB: d5tt7a2
  automated match to d3tuca_
  complexed with 7kf

More info for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK:

Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK first appeared in SCOP 1.71
Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK appears in SCOPe 2.05
Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK appears in SCOPe 2.07
Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK appears in the current release, SCOPe 2.08