Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1931488Protein Tyrosine-protein kinase SYK [118131] (1 species)
    PTK group; SYK/ZAP-70 subfamily; non-membrane spanning protein tyrosine kinase
  7. 1931489Species Human (Homo sapiens) [TaxId:9606] [118132] (52 PDB entries)
    Uniprot P43405 363-635 # structure of the SH2 domain tandem region (9-265) is also known (55576)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1xba:
  2. Domain(s) for 1xbb:
    • 1931491Domain d1xbba_: 1xbb A: [115077]
      Structural genomics target
      complexed with sti
  3. Domain(s) for 1xbc:
    • 1931515Domain d1xbca_: 1xbc A: [115078]
      Structural genomics target
      complexed with stu
  4. Domain(s) for 3emg:
  5. Domain(s) for 3fqe:
  6. Domain(s) for 3fqh:
    1. 1931521Domain d3fqha_: 3fqh A: [175977]
      automated match to d1xbba_
      complexed with 057
    2. 1931522Domain d3fqhb_: 3fqh B: [175978]
      automated match to d1xbba_
      complexed with 057
  7. Domain(s) for 3fqs:
  8. Domain(s) for 3srv:
    1. 1931497Domain d3srva_: 3srv A: [185500]
      automated match to d1xbaa_
      complexed with gol, s19
    2. 1931498Domain d3srvb_: 3srv B: [185501]
      automated match to d1xbaa_
      complexed with gol, s19
  9. Domain(s) for 3tub:
  10. Domain(s) for 3tuc:
  11. Domain(s) for 3tud:
  12. Domain(s) for 3vf8:
  13. Domain(s) for 3vf9:
  14. Domain(s) for 4dfl:
  15. Domain(s) for 4dfn:
  16. Domain(s) for 4f4p:
  17. Domain(s) for 4fl1:
  18. Domain(s) for 4fyn:
  19. Domain(s) for 4fyo:
  20. Domain(s) for 4fz6:
  21. Domain(s) for 4fz7:
  22. Domain(s) for 4gfg:
  23. Domain(s) for 4i0r:
  24. Domain(s) for 4i0s:
  25. Domain(s) for 4i0t:
  26. Domain(s) for 4puz:
    1. 1931529Domain d4puza_: 4puz A: [257562]
      automated match to d1xbba_
      complexed with cg9
    2. 1931530Domain d4puzb_: 4puz B: [257563]
      automated match to d1xbba_
      complexed with cg9
  27. Domain(s) for 4pv0:
  28. Domain(s) for 4rss:
  29. Domain(s) for 4rx7:
  30. Domain(s) for 4rx8:
  31. Domain(s) for 4rx9:
  32. Domain(s) for 4xg2:
  33. Domain(s) for 4xg3:
    1. 1931540Domain d4xg3a_: 4xg3 A: [280185]
      automated match to d3tuca_
      complexed with x3g
    2. 1931541Domain d4xg3b_: 4xg3 B: [280189]
      automated match to d3tuca_
      complexed with x3g
  34. Domain(s) for 4xg4:
  35. Domain(s) for 4xg5:
    1. 1931545Domain d4xg5a_: 4xg5 A: [280190]
      automated match to d3tuca_
      complexed with x5g
    2. 1931546Domain d4xg5b_: 4xg5 B: [280192]
      automated match to d3tuca_
      complexed with x5g
  36. Domain(s) for 4xg6:
  37. Domain(s) for 4xg7:
  38. Domain(s) for 4xg8:
    1. 1931543Domain d4xg8a_: 4xg8 A: [280183]
      automated match to d3tuca_
      complexed with x8g
    2. 1931544Domain d4xg8c_: 4xg8 C: [280187]
      automated match to d3tuca_
      complexed with x8g
  39. Domain(s) for 4xg9:
    1. 1931547Domain d4xg9a_: 4xg9 A: [280191]
      automated match to d3tuca_
      complexed with x9g
    2. 1931548Domain d4xg9b_: 4xg9 B: [280184]
      automated match to d3tuca_
      complexed with x9g
  40. Domain(s) for 4yjo:
  41. Domain(s) for 4yjp:
  42. Domain(s) for 4yjq:
  43. Domain(s) for 4yjr:
  44. Domain(s) for 4yjs:
  45. Domain(s) for 4yjt:
  46. Domain(s) for 4yju:
  47. Domain(s) for 4yjv:
  48. Domain(s) for 5c26:
  49. Domain(s) for 5c27:
  50. Domain(s) for 5cxh:
  51. Domain(s) for 5cxz:
  52. Domain(s) for 5cy3:

More info for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK: