Lineage for d5c26a1 (5c26 A:363-635)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220835Protein Tyrosine-protein kinase SYK [118131] (1 species)
    PTK group; SYK/ZAP-70 subfamily; non-membrane spanning protein tyrosine kinase
  7. 2220836Species Human (Homo sapiens) [TaxId:9606] [118132] (60 PDB entries)
    Uniprot P43405 363-635 # structure of the SH2 domain tandem region (9-265) is also known (55576)
  8. 2220881Domain d5c26a1: 5c26 A:363-635 [277851]
    Other proteins in same PDB: d5c26a2
    automated match to d3tuca_
    complexed with 50h

Details for d5c26a1

PDB Entry: 5c26 (more details), 1.95 Å

PDB Description: crystal structure of syk in complex with compound 1
PDB Compounds: (A:) Tyrosine-protein kinase SYK

SCOPe Domain Sequences for d5c26a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5c26a1 d.144.1.7 (A:363-635) Tyrosine-protein kinase SYK {Human (Homo sapiens) [TaxId: 9606]}
vyldrklltledkelgsgnfgtvkkgyyqmkkvvktvavkilkneandpalkdellaean
vmqqldnpyivrmigiceaeswmlvmemaelgplnkylqqnrhvkdkniielvhqvsmgm
kyleesnfvhrdlaarnvllvtqhyakisdfglskalradenyykaqthgkwpvkwyape
cinyykfssksdvwsfgvlmweafsygqkpyrgmkgsevtamlekgermgcpagcpremy
dlmnlcwtydvenrpgfaavelrlrnyyydvvn

SCOPe Domain Coordinates for d5c26a1:

Click to download the PDB-style file with coordinates for d5c26a1.
(The format of our PDB-style files is described here.)

Timeline for d5c26a1: