PDB entry 4yjp

View 4yjp on RCSB PDB site
Description: the kinase domain of human spleen tyrosine (syk) in complex with gtc000223
Class: transferase
Keywords: syk, non-receptor tyrosine kinase, spleen tyrosine kinase, transferase, phosphorylation, transferase-transferase inhibitor complex
Deposited on 2015-03-03, released 2015-09-30
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-09-30, with a file datestamp of 2015-09-25.
Experiment type: XRAY
Resolution: 1.83 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase SYK
    Species: Homo sapiens [TaxId:9606]
    Gene: SYK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4yjpa_
  • Heterogens: 4DL, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4yjpA (A:)
peeirpkevyldrklltledkelgsgnfgtvkkgyyqmkkvvktvavkilkneandpalk
dellaeanvmqqldnpyivrmigiceaeswmlvmemaelgplnkylqqnrhvkdkniiel
vhqvsmgmkyleesnfvhrdlaarnvllvtqhyakisdfglskalradenyykaqthgkw
pvkwyapecinyykfssksdvwsfgvlmweafsygqkpyrgmkgsevtamlekgermgcp
agcpremydlmnlcwtydvenrpgfaavelrlrnyyydvvn

    Sequence, based on observed residues (ATOM records): (download) 
    >4yjpA (A:)
yldrklltledkelgsgnfgtvkkgyyqmkkvvktvavkilkndpalkdellaeanvmqq
ldnpyivrmigiceaeswmlvmemaelgplnkylqqnrhvkdkniielvhqvsmgmkyle
esnfvhrdlaarnvllvtqhyakisdfglskalradenyykagkwpvkwyapecinyykf
ssksdvwsfgvlmweafsygqkpyrgmkgsevtamlekgermgcpagcpremydlmnlcw
tydvenrpgfaavelrlrnyyyd