Lineage for Protein: Class sigma GST

  1. Root: SCOP 1.75
  2. 814173Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 833461Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
    core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest
  4. 833462Superfamily c.47.1: Thioredoxin-like [52833] (23 families) (S)
  5. 833722Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain [52862] (18 proteins)
  6. 834130Protein Class sigma GST [81362] (5 species)

Species:

  1. 834131Fruit fly (Drosophila melanogaster) [TaxId:7227] [82427] (1 PDB entry)
  2. 834134Heligmosomoides polygyrus [TaxId:6339] [110608] (1 PDB entry)
    Uniprot Q9NJQ6 # Fragment
  3. 834143Human (Homo sapiens) [TaxId:9606] [89705] (11 PDB entries)
    Uniprot O60760
    synonym: hematopoietic prostaglandin D synthase
    1. Domains for 1iyh:
      1. 834148Domain d1iyha2: 1iyh A:2-75 [83791]
        Other proteins in same PDB: d1iyha1, d1iyhb1, d1iyhc1, d1iyhd1
      2. 834149Domain d1iyhb2: 1iyh B:202-275 [83793]
        Other proteins in same PDB: d1iyha1, d1iyhb1, d1iyhc1, d1iyhd1
      3. 834150Domain d1iyhc2: 1iyh C:402-475 [83795]
        Other proteins in same PDB: d1iyha1, d1iyhb1, d1iyhc1, d1iyhd1
      4. 834151Domain d1iyhd2: 1iyh D:602-675 [83797]
        Other proteins in same PDB: d1iyha1, d1iyhb1, d1iyhc1, d1iyhd1
        complexed with gsh, mg
    2. Domains for 1iyi:
      1. 834152Domain d1iyia2: 1iyi A:2-75 [83799]
        Other proteins in same PDB: d1iyia1, d1iyib1, d1iyic1, d1iyid1
      2. 834153Domain d1iyib2: 1iyi B:202-275 [83801]
        Other proteins in same PDB: d1iyia1, d1iyib1, d1iyic1, d1iyid1
      3. 834154Domain d1iyic2: 1iyi C:402-475 [83803]
        Other proteins in same PDB: d1iyia1, d1iyib1, d1iyic1, d1iyid1
      4. 834155Domain d1iyid2: 1iyi D:602-675 [83805]
        Other proteins in same PDB: d1iyia1, d1iyib1, d1iyic1, d1iyid1
        complexed with ca, gsh
    3. Domains for 1v40:
      1. 834168Domain d1v40a2: 1v40 A:2-75 [113513]
        Other proteins in same PDB: d1v40a1, d1v40b1, d1v40c1, d1v40d1
      2. 834169Domain d1v40b2: 1v40 B:202-275 [113515]
        Other proteins in same PDB: d1v40a1, d1v40b1, d1v40c1, d1v40d1
      3. 834170Domain d1v40c2: 1v40 C:402-475 [113517]
        Other proteins in same PDB: d1v40a1, d1v40b1, d1v40c1, d1v40d1
      4. 834171Domain d1v40d2: 1v40 D:602-675 [113519]
        Other proteins in same PDB: d1v40a1, d1v40b1, d1v40c1, d1v40d1
        complexed with cry, gsh, mg, o16
    4. Domains for 2cvd:
      1. 834144Domain d2cvda2: 2cvd A:2-75 [130862]
        Other proteins in same PDB: d2cvda1, d2cvdb1, d2cvdc1, d2cvdd1
        automatically matched to d1iyha2
        complexed with gol, gsh, hql, mg
      2. 834145Domain d2cvdb2: 2cvd B:2-75 [130864]
        Other proteins in same PDB: d2cvda1, d2cvdb1, d2cvdc1, d2cvdd1
        automatically matched to d1iyha2
        complexed with gol, gsh, hql, mg
      3. 834146Domain d2cvdc2: 2cvd C:2-75 [130866]
        Other proteins in same PDB: d2cvda1, d2cvdb1, d2cvdc1, d2cvdd1
        automatically matched to d1iyha2
        complexed with gol, gsh, hql, mg
      4. 834147Domain d2cvdd2: 2cvd D:2-75 [130868]
        Other proteins in same PDB: d2cvda1, d2cvdb1, d2cvdc1, d2cvdd1
        automatically matched to d1iyha2
        complexed with gol, gsh, hql, mg
    5. Domains for 2vcq:
      1. 834156Domain d2vcqa2: 2vcq A:2-75 [152923]
        Other proteins in same PDB: d2vcqa1, d2vcqb1, d2vcqc1, d2vcqd1
        automatically matched to d1iyha2
        complexed with d25, gsh
      2. 834157Domain d2vcqb2: 2vcq B:2-75 [152925]
        Other proteins in same PDB: d2vcqa1, d2vcqb1, d2vcqc1, d2vcqd1
        automatically matched to d1iyha2
        complexed with d25, gsh
      3. 834158Domain d2vcqc2: 2vcq C:2-75 [152927]
        Other proteins in same PDB: d2vcqa1, d2vcqb1, d2vcqc1, d2vcqd1
        automatically matched to d1iyha2
        complexed with d25, gsh
      4. 834159Domain d2vcqd2: 2vcq D:2-75 [152929]
        Other proteins in same PDB: d2vcqa1, d2vcqb1, d2vcqc1, d2vcqd1
        automatically matched to d1iyha2
        complexed with d25, gsh
    6. Domains for 2vcw:
      1. 834164Domain d2vcwa2: 2vcw A:2-75 [152931]
        Other proteins in same PDB: d2vcwa1, d2vcwb1, d2vcwc1, d2vcwd1
        automatically matched to d1iyha2
        complexed with gsh, zza
      2. 834165Domain d2vcwb2: 2vcw B:2-75 [152933]
        Other proteins in same PDB: d2vcwa1, d2vcwb1, d2vcwc1, d2vcwd1
        automatically matched to d1iyha2
        complexed with gsh, zza
      3. 834166Domain d2vcwc2: 2vcw C:2-75 [152935]
        Other proteins in same PDB: d2vcwa1, d2vcwb1, d2vcwc1, d2vcwd1
        automatically matched to d1iyha2
        complexed with gsh, zza
      4. 834167Domain d2vcwd2: 2vcw D:2-75 [152937]
        Other proteins in same PDB: d2vcwa1, d2vcwb1, d2vcwc1, d2vcwd1
        automatically matched to d1iyha2
        complexed with gsh, zza
    7. Domains for 2vcx:
      1. 834172Domain d2vcxa2: 2vcx A:2-75 [152939]
        Other proteins in same PDB: d2vcxa1, d2vcxb1, d2vcxc1, d2vcxd1
        automatically matched to d1iyha2
        complexed with d26, gsh, mg
      2. 834173Domain d2vcxb2: 2vcx B:2-75 [152941]
        Other proteins in same PDB: d2vcxa1, d2vcxb1, d2vcxc1, d2vcxd1
        automatically matched to d1iyha2
        complexed with d26, gsh, mg
      3. 834174Domain d2vcxc2: 2vcx C:2-75 [152943]
        Other proteins in same PDB: d2vcxa1, d2vcxb1, d2vcxc1, d2vcxd1
        automatically matched to d1iyha2
        complexed with d26, gsh, mg
      4. 834175Domain d2vcxd2: 2vcx D:2-75 [152945]
        Other proteins in same PDB: d2vcxa1, d2vcxb1, d2vcxc1, d2vcxd1
        automatically matched to d1iyha2
        complexed with d26, gsh, mg
    8. Domains for 2vcz:
      1. 834160Domain d2vcza2: 2vcz A:2-75 [152947]
        Other proteins in same PDB: d2vcza1, d2vczb1, d2vczc1, d2vczd1
        automatically matched to d1iyha2
        complexed with gsh, vc3
      2. 834161Domain d2vczb2: 2vcz B:2-75 [152949]
        Other proteins in same PDB: d2vcza1, d2vczb1, d2vczc1, d2vczd1
        automatically matched to d1iyha2
        complexed with gsh, vc3
      3. 834162Domain d2vczc2: 2vcz C:2-75 [152951]
        Other proteins in same PDB: d2vcza1, d2vczb1, d2vczc1, d2vczd1
        automatically matched to d1iyha2
        complexed with gsh, vc3
      4. 834163Domain d2vczd2: 2vcz D:2-75 [152953]
        Other proteins in same PDB: d2vcza1, d2vczb1, d2vczc1, d2vczd1
        automatically matched to d1iyha2
        complexed with gsh, vc3
    9. Domains for 2vd0:
      1. 834178Domain d2vd0a2: 2vd0 A:2-75 [152955]
        Other proteins in same PDB: d2vd0a1, d2vd0b1, d2vd0c1, d2vd0d1
        automatically matched to d1iyha2
        complexed with d27, gol, gsh
      2. 834179Domain d2vd0b2: 2vd0 B:2-75 [152957]
        Other proteins in same PDB: d2vd0a1, d2vd0b1, d2vd0c1, d2vd0d1
        automatically matched to d1iyha2
        complexed with d27, gol, gsh
      3. 834180Domain d2vd0c2: 2vd0 C:2-75 [152959]
        Other proteins in same PDB: d2vd0a1, d2vd0b1, d2vd0c1, d2vd0d1
        automatically matched to d1iyha2
        complexed with d27, gol, gsh
      4. 834181Domain d2vd0d2: 2vd0 D:2-75 [152961]
        Other proteins in same PDB: d2vd0a1, d2vd0b1, d2vd0c1, d2vd0d1
        automatically matched to d1iyha2
        complexed with d27, gol, gsh
    10. Domains for 2vd1:
      1. 834182Domain d2vd1a2: 2vd1 A:2-75 [152963]
        Other proteins in same PDB: d2vd1a1, d2vd1b1, d2vd1c1, d2vd1d1
        automatically matched to d1iyha2
        complexed with d28, gsh, mg
      2. 834183Domain d2vd1b2: 2vd1 B:2-75 [152965]
        Other proteins in same PDB: d2vd1a1, d2vd1b1, d2vd1c1, d2vd1d1
        automatically matched to d1iyha2
        complexed with d28, gsh, mg
      3. 834184Domain d2vd1c2: 2vd1 C:2-75 [152967]
        Other proteins in same PDB: d2vd1a1, d2vd1b1, d2vd1c1, d2vd1d1
        automatically matched to d1iyha2
        complexed with d28, gsh, mg
      4. 834185Domain d2vd1d2: 2vd1 D:2-75 [152969]
        Other proteins in same PDB: d2vd1a1, d2vd1b1, d2vd1c1, d2vd1d1
        automatically matched to d1iyha2
        complexed with d28, gsh, mg
    11. Domains for 3ee2:
      1. 834176Domain d3ee2a2: 3ee2 A:2-75 [158118]
        Other proteins in same PDB: d3ee2a1, d3ee2b1
        automatically matched to d1iyha2
        complexed with gtt, mg, nzo
      2. 834177Domain d3ee2b2: 3ee2 B:2-75 [158120]
        Other proteins in same PDB: d3ee2a1, d3ee2b1
        automatically matched to d1iyha2
        complexed with gtt, mg, nzo
  4. 834186Rat (Rattus norvegicus) [TaxId:10116] [52875] (1 PDB entry)
    synonym: hematopoietic prostaglandin D synthase
  5. 834189Squid (Ommastrephes sloani pacificus) [TaxId:6634] [52876] (2 PDB entries)
    1. Domain for 1gsq:
    2. Domain for 2gsq:

More info for Protein Class sigma GST from c.47.1.5: Glutathione S-transferase (GST), N-terminal domain

Timeline for Protein Class sigma GST from c.47.1.5: Glutathione S-transferase (GST), N-terminal domain: