PDB entry 2vcw

View 2vcw on RCSB PDB site
Description: complex structure of prostaglandin d2 synthase at 1.95a.
Class: isomerase
Keywords: prostaglandin biosynthesis, fatty acid biosynthesis, prostaglandin d2 synthase, pgds, asthma, cytoplasm, isomerase, lipid synthesis
Deposited on 2007-09-27, released 2008-04-15
The last revision prior to the SCOP 1.75 freeze date was dated 2008-04-15, with a file datestamp of 2008-04-11.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.20754
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutathione-requiring prostaglandin d synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vcwa1, d2vcwa2
  • Chain 'B':
    Compound: glutathione-requiring prostaglandin d synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vcwb1, d2vcwb2
  • Chain 'C':
    Compound: glutathione-requiring prostaglandin d synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vcwc1, d2vcwc2
  • Chain 'D':
    Compound: glutathione-requiring prostaglandin d synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2vcwd1, d2vcwd2
  • Heterogens: GSH, ZZA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vcwA (A:)
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lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
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    Sequence, based on observed residues (ATOM records): (download) 
    >2vcwA (A:)
pnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdgltl
hqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnellt
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  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vcwB (B:)
mpnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdglt
lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
vqaipavanwikrrpqtkl

    Sequence, based on observed residues (ATOM records): (download) 
    >2vcwB (B:)
pnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdgltl
hqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnellt
ynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkkv
qaipavanwikrrpqtkl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2vcwC (C:)
mpnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdglt
lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
vqaipavanwikrrpqtkl

    Sequence, based on observed residues (ATOM records): (download) 
    >2vcwC (C:)
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ldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkkvqaipavanw
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  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vcwD (D:)
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lhqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnell
tynaphlmqdldtylggrewlignsvtwadfyweicsttllvfkpdlldnhprlvtlrkk
vqaipavanwikrrpqtkl

    Sequence, based on observed residues (ATOM records): (download) 
    >2vcwD (D:)
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