PDB entry 1v40

View 1v40 on RCSB PDB site
Description: First Inhibitor Complex Structure of Human Hematopoietic Prostaglandin D Synthase
Class: isomerase
Keywords: hematopoietic prostaglandin d synthase, pgds, gst, sigma-2 class gst, ligase
Deposited on 2003-11-07, released 2004-11-07
The last revision prior to the SCOP 1.75 freeze date was dated 2004-11-07, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.195
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutathione-requiring prostaglandin d synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60760
      • conflict (142)
    Domains in SCOP 1.75: d1v40a1, d1v40a2
  • Chain 'B':
    Compound: glutathione-requiring prostaglandin d synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60760
      • conflict (142)
    Domains in SCOP 1.75: d1v40b1, d1v40b2
  • Chain 'C':
    Compound: glutathione-requiring prostaglandin d synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60760
      • conflict (142)
    Domains in SCOP 1.75: d1v40c1, d1v40c2
  • Chain 'D':
    Compound: glutathione-requiring prostaglandin d synthase
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60760 (0-197)
      • conflict (142)
    Domains in SCOP 1.75: d1v40d1, d1v40d2
  • Heterogens: MG, GSH, O16, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1v40A (A:)
pnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdgltl
hqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnellt
ynaphlmqdldtylggrewligmsvtwadfyweicsttllvfkpdlldnhprlvtlrkkv
qaipavanwikrrpqtkl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1v40B (B:)
pnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdgltl
hqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnellt
ynaphlmqdldtylggrewligmsvtwadfyweicsttllvfkpdlldnhprlvtlrkkv
qaipavanwikrrpqtkl

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1v40C (C:)
pnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdgltl
hqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnellt
ynaphlmqdldtylggrewligmsvtwadfyweicsttllvfkpdlldnhprlvtlrkkv
qaipavanwikrrpqtkl

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1v40D (D:)
pnykltyfnmrgraeiiryifayldiqyedhrieqadwpeikstlpfgkipilevdgltl
hqslaiaryltkntdlagntemeqchvdaivdtlddfmscfpwaekkqdvkeqmfnellt
ynaphlmqdldtylggrewligmsvtwadfyweicsttllvfkpdlldnhprlvtlrkkv
qaipavanwikrrpqtkl