Lineage for Protein: dTDP-glucose 4,6-dehydratase (RmlB)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2841004Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2841005Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2841375Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

    has additional subdomain(s) that are not in the common domain
  6. 2842012Protein dTDP-glucose 4,6-dehydratase (RmlB) [51755] (4 species)

Species:

  1. 2842013Escherichia coli [TaxId:562] [51756] (1 PDB entry)
    • Domains for 1bxk:
      1. 2842014Domain d1bxka_: 1bxk A: [29803]
        complexed with nad
        has additional subdomain(s) that are not in the common domain
      2. 2842015Domain d1bxkb_: 1bxk B: [29804]
        complexed with nad
        has additional subdomain(s) that are not in the common domain
  2. 2842016Salmonella enterica [TaxId:28901] [63925] (1 PDB entry)
    • Domains for 1g1a:
      1. 2842017Domain d1g1aa_: 1g1a A: [60198]
        complexed with nad, so4
        has additional subdomain(s) that are not in the common domain
      2. 2842018Domain d1g1ab_: 1g1a B: [60199]
        complexed with nad, so4
        has additional subdomain(s) that are not in the common domain
      3. 2842019Domain d1g1ac_: 1g1a C: [60200]
        complexed with nad, so4
        has additional subdomain(s) that are not in the common domain
      4. 2842020Domain d1g1ad_: 1g1a D: [60201]
        complexed with nad, so4
        has additional subdomain(s) that are not in the common domain
  3. 2842021Streptococcus suis, serotype 2 [TaxId:1307] [69406] (6 PDB entries)
    1. Domains for 1kep:
      1. 2842032Domain d1kepa_: 1kep A: [68536]
        complexed with nad, so4, tdx
        has additional subdomain(s) that are not in the common domain
      2. 2842033Domain d1kepb_: 1kep B: [68537]
        complexed with nad, so4, tdx
        has additional subdomain(s) that are not in the common domain
    2. Domains for 1ker:
      1. 2842028Domain d1kera_: 1ker A: [68538]
        complexed with dau, nad, so4
        has additional subdomain(s) that are not in the common domain
      2. 2842029Domain d1kerb_: 1ker B: [68539]
        complexed with dau, nad, so4
        has additional subdomain(s) that are not in the common domain
    3. Domains for 1ket:
      1. 2842022Domain d1keta_: 1ket A: [68540]
        complexed with nad, tyd
        has additional subdomain(s) that are not in the common domain
      2. 2842023Domain d1ketb_: 1ket B: [68541]
        complexed with nad, tyd
        has additional subdomain(s) that are not in the common domain
    4. Domains for 1keu:
      1. 2842030Domain d1keua_: 1keu A: [68542]
        complexed with dau, nad
        has additional subdomain(s) that are not in the common domain
      2. 2842031Domain d1keub_: 1keu B: [68543]
        complexed with dau, nad
        has additional subdomain(s) that are not in the common domain
    5. Domains for 1kew:
      1. 2842024Domain d1kewa_: 1kew A: [68544]
        complexed with gol, nad, tyd
        has additional subdomain(s) that are not in the common domain
      2. 2842025Domain d1kewb_: 1kew B: [68545]
        complexed with gol, nad, tyd
        has additional subdomain(s) that are not in the common domain
    6. Domains for 1oc2:
      1. 2842026Domain d1oc2a_: 1oc2 A: [92765]
        complexed with nad, so4, tdx
        has additional subdomain(s) that are not in the common domain
      2. 2842027Domain d1oc2b_: 1oc2 B: [92766]
        complexed with nad, so4, tdx
        has additional subdomain(s) that are not in the common domain
  4. 2842034Streptomyces venezuelae [TaxId:54571] [102133] (2 PDB entries)
    1. Domain for 1r66:
      • 2842036Domain d1r66a_: 1r66 A: [97146]
        complexed with cl, nad, tyd
        has additional subdomain(s) that are not in the common domain
    2. Domain for 1r6d:
      • 2842035Domain d1r6da_: 1r6d A: [97148]
        complexed with dau, nad; mutant
        has additional subdomain(s) that are not in the common domain

More info for Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases: