Lineage for Protein: dTDP-glucose 4,6-dehydratase (RmlB)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2426096Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2426097Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2426443Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2427003Protein dTDP-glucose 4,6-dehydratase (RmlB) [51755] (4 species)

Species:

  1. 2427004Escherichia coli [TaxId:562] [51756] (1 PDB entry)
  2. 2427007Salmonella enterica [TaxId:28901] [63925] (1 PDB entry)
  3. 2427012Streptococcus suis, serotype 2 [TaxId:1307] [69406] (6 PDB entries)
    1. Domains for 1kep:
      1. 2427023Domain d1kepa_: 1kep A: [68536]
        complexed with nad, so4, tdx
      2. 2427024Domain d1kepb_: 1kep B: [68537]
        complexed with nad, so4, tdx
    2. Domains for 1ker:
      1. 2427019Domain d1kera_: 1ker A: [68538]
        complexed with dau, nad, so4
      2. 2427020Domain d1kerb_: 1ker B: [68539]
        complexed with dau, nad, so4
    3. Domains for 1ket:
      1. 2427015Domain d1keta_: 1ket A: [68540]
        complexed with nad, tyd
      2. 2427016Domain d1ketb_: 1ket B: [68541]
        complexed with nad, tyd
    4. Domains for 1keu:
      1. 2427021Domain d1keua_: 1keu A: [68542]
        complexed with dau, nad
      2. 2427022Domain d1keub_: 1keu B: [68543]
        complexed with dau, nad
    5. Domains for 1kew:
      1. 2427017Domain d1kewa_: 1kew A: [68544]
        complexed with gol, nad, tyd
      2. 2427018Domain d1kewb_: 1kew B: [68545]
        complexed with gol, nad, tyd
    6. Domains for 1oc2:
      1. 2427013Domain d1oc2a_: 1oc2 A: [92765]
        complexed with nad, so4, tdx
      2. 2427014Domain d1oc2b_: 1oc2 B: [92766]
        complexed with nad, so4, tdx
  4. 2427025Streptomyces venezuelae [TaxId:54571] [102133] (2 PDB entries)
    1. Domain for 1r66:
    2. Domain for 1r6d:

More info for Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein dTDP-glucose 4,6-dehydratase (RmlB) from c.2.1.2: Tyrosine-dependent oxidoreductases: