Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) |
Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 has additional subdomain(s) that are not in the common domain |
Protein dTDP-glucose 4,6-dehydratase (RmlB) [51755] (4 species) |
Species Streptomyces venezuelae [TaxId:54571] [102133] (2 PDB entries) |
Domain d1r66a_: 1r66 A: [97146] complexed with cl, nad, tyd has additional subdomain(s) that are not in the common domain |
Domain d1r6da_: 1r6d A: [97148] complexed with dau, nad; mutant has additional subdomain(s) that are not in the common domain |
Timeline for Species Streptomyces venezuelae [TaxId:54571] from c.2.1.2 dTDP-glucose 4,6-dehydratase (RmlB):