|  | Class b: All beta proteins [48724] (176 folds) | 
|  | Fold b.7: C2 domain-like [49561] (5 superfamilies) sandwich; 8 strands in 2 sheets; greek-key | 
|  | Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families)  two constituent families are related by circular permutation | 
|  | Family b.7.1.1: PLC-like (P variant) [49563] (12 proteins) | 
|  | Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species) | 
|  | Species Human (Homo sapiens) [TaxId:9606] [49572] (56 PDB entries) | 
|  | Domain d1e8ya2: 1e8y A:357-522 [23187] Other proteins in same PDB: d1e8ya1, d1e8ya3, d1e8ya4 | 
|  | Domain d1e8za2: 1e8z A:357-522 [23188] Other proteins in same PDB: d1e8za1, d1e8za3, d1e8za4 complexed with stu | 
|  | Domain d1he8a2: 1he8 A:353-524 [23189] Other proteins in same PDB: d1he8a1, d1he8a3, d1he8a4, d1he8b_ complexed with gnp, mg | 
|  | Domain d2a4za2: 2a4z A:357-522 [203391] Other proteins in same PDB: d2a4za1, d2a4za3, d2a4za4 automated match to d1e8ya2 complexed with bym | 
|  | Domain d2a5ua2: 2a5u A:357-522 [203395] Other proteins in same PDB: d2a5ua1, d2a5ua3, d2a5ua4 automated match to d1e8ya2 complexed with qyt | 
|  | Domain d2chwa2: 2chw A:357-522 [203788] Other proteins in same PDB: d2chwa1, d2chwa3, d2chwa4 automated match to d1e8ya2 complexed with 039 | 
|  | Domain d2chxa2: 2chx A:357-522 [203792] Other proteins in same PDB: d2chxa1, d2chxa3, d2chxa4 automated match to d1e8ya2 complexed with 090 | 
|  | Domain d2chza2: 2chz A:357-522 [203796] Other proteins in same PDB: d2chza1, d2chza3, d2chza4 automated match to d1e8ya2 complexed with 093 | 
|  | Domain d2v4la2: 2v4l A:357-522 [206204] Other proteins in same PDB: d2v4la1, d2v4la3, d2v4la4 automated match to d1e8ya2 complexed with abj | 
|  | Domain d3apca2: 3apc A:357-521 [245173] Other proteins in same PDB: d3apca1, d3apca3, d3apca4 automated match to d1e8wa2 complexed with mmd, so4 | 
|  | Domain d3apda2: 3apd A:357-522 [245177] Other proteins in same PDB: d3apda1, d3apda3, d3apda4 automated match to d1e8wa2 complexed with mmy, so4 | 
|  | Domain d3apfa2: 3apf A:357-522 [245181] Other proteins in same PDB: d3apfa1, d3apfa3, d3apfa4 automated match to d1e8wa2 complexed with bmw, so4 | 
|  | Domain d3csfa2: 3csf A:357-522 [245525] Other proteins in same PDB: d3csfa1, d3csfa3, d3csfa4 automated match to d1e8wa2 complexed with dw2 | 
|  | Domain d3dpda2: 3dpd A:357-522 [209251] Other proteins in same PDB: d3dpda1, d3dpda3, d3dpda4 automated match to d1e8ya2 complexed with 41a | 
|  | Domain d3enea2: 3ene A:357-522 [245882] Other proteins in same PDB: d3enea1, d3enea3, d3enea4 automated match to d1e8wa2 complexed with npz | 
|  | Domain d3ibea2: 3ibe A:357-522 [211566] Other proteins in same PDB: d3ibea1, d3ibea3, d3ibea4 automated match to d1e8ya2 complexed with l64, so4 | 
|  | Domain d3l08a2: 3l08 A:352-520 [247308] Other proteins in same PDB: d3l08a1, d3l08a3, d3l08a4 automated match to d1e8wa2 complexed with so4, zig | 
|  | Domain d3l13a2: 3l13 A:357-522 [247312] Other proteins in same PDB: d3l13a1, d3l13a3, d3l13a4 automated match to d1e8wa2 complexed with jzw | 
|  | Domain d3l16a2: 3l16 A:357-522 [247316] Other proteins in same PDB: d3l16a1, d3l16a3, d3l16a4 automated match to d1e8wa2 complexed with jzx | 
|  | Domain d3l17a2: 3l17 A:357-522 [247320] Other proteins in same PDB: d3l17a1, d3l17a3, d3l17a4 automated match to d1e8wa2 complexed with jzy | 
|  | Domain d3lj3a2: 3lj3 A:357-522 [212906] Other proteins in same PDB: d3lj3a1, d3lj3a3, d3lj3a4 automated match to d1e8ya2 complexed with so4, wye | 
|  | Domain d3mjwa2: 3mjw A:357-522 [213287] Other proteins in same PDB: d3mjwa1, d3mjwa3, d3mjwa4 automated match to d1e8ya2 complexed with wyf | 
|  | Domain d3ml8a2: 3ml8 A:357-522 [213319] Other proteins in same PDB: d3ml8a1, d3ml8a3, d3ml8a4 automated match to d1e8ya2 complexed with ml8 | 
|  | Domain d3ml9a2: 3ml9 A:357-522 [213323] Other proteins in same PDB: d3ml9a1, d3ml9a3, d3ml9a4 automated match to d1e8ya2 complexed with ml9 | 
|  | Domain d3nzsa2: 3nzs A:353-521 [248104] Other proteins in same PDB: d3nzsa1, d3nzsa3, d3nzsa4 automated match to d1e8wa2 complexed with nzs | 
|  | Domain d3nzua2: 3nzu A:357-521 [248108] Other proteins in same PDB: d3nzua1, d3nzua3, d3nzua4 automated match to d1e8wa2 complexed with nzu | 
|  | Domain d3oawa2: 3oaw A:353-524 [248155] Other proteins in same PDB: d3oawa1, d3oawa3, d3oawa4 automated match to d1e8wa2 complexed with oaw | 
|  | Domain d3prea2: 3pre A:353-522 [248624] Other proteins in same PDB: d3prea1, d3prea3, d3prea4 automated match to d1e8wa2 complexed with 3re | 
|  | Domain d3prza2: 3prz A:352-524 [248634] Other proteins in same PDB: d3prza1, d3prza3, d3prza4 automated match to d1e8wa2 complexed with 3rz | 
|  | Domain d3ps6a2: 3ps6 A:352-523 [248641] Other proteins in same PDB: d3ps6a1, d3ps6a3, d3ps6a4 automated match to d1e8wa2 complexed with 3ps | 
|  | Domain d3qaqa2: 3qaq A:352-522 [248827] Other proteins in same PDB: d3qaqa1, d3qaqa3, d3qaqa4 automated match to d1e8wa2 complexed with qaq, so4 | 
|  | Domain d3qara2: 3qar A:353-522 [248831] Other proteins in same PDB: d3qara1, d3qara3, d3qara4 automated match to d1e8wa2 complexed with qar, so4 | 
|  | Domain d3qk0a2: 3qk0 A:357-522 [248916] Other proteins in same PDB: d3qk0a1, d3qk0a3, d3qk0a4 automated match to d1e8wa2 complexed with qk0, so4 | 
|  | Domain d3s2aa2: 3s2a A:352-522 [249286] Other proteins in same PDB: d3s2aa1, d3s2aa3, d3s2aa4 automated match to d1e8wa2 complexed with 2nq, so4 | 
|  | Domain d3tjpa2: 3tjp A:357-522 [216843] Other proteins in same PDB: d3tjpa1, d3tjpa3, d3tjpa4 automated match to d1e8ya2 complexed with 13k, so4 | 
|  | Domain d3tl5a2: 3tl5 A:357-524 [249950] Other proteins in same PDB: d3tl5a1, d3tl5a3, d3tl5a4 automated match to d1e8wa2 complexed with 980 | 
|  | Domain d4dk5a2: 4dk5 A:352-522 [251469] Other proteins in same PDB: d4dk5a1, d4dk5a3, d4dk5a4 automated match to d1e8wa2 complexed with 0ko, so4 | 
|  | Domain d4ezja2: 4ezj A:357-522 [251834] Other proteins in same PDB: d4ezja1, d4ezja3, d4ezja4 automated match to d1e8wa2 complexed with 0sc | 
|  | Domain d4ezka2: 4ezk A:357-522 [251838] Other proteins in same PDB: d4ezka1, d4ezka3, d4ezka4 automated match to d1e8wa2 complexed with 0sd | 
|  | Domain d4ezla2: 4ezl A:357-522 [251842] Other proteins in same PDB: d4ezla1, d4ezla3, d4ezla4 automated match to d1e8wa2 complexed with 0se | 
|  | Domain d4f1sa2: 4f1s A:352-522 [251864] Other proteins in same PDB: d4f1sa1, d4f1sa3, d4f1sa4 automated match to d1e8wa2 complexed with f1s, so4 | 
|  | Domain d4fhja2: 4fhj A:357-522 [251971] Other proteins in same PDB: d4fhja1, d4fhja3, d4fhja4 automated match to d1e8wa2 complexed with 0tz, so4 | 
|  | Domain d4fhka2: 4fhk A:357-522 [251975] Other proteins in same PDB: d4fhka1, d4fhka3, d4fhka4 automated match to d1e8wa2 complexed with 0u0, so4 | 
|  | Domain d4fjya2: 4fjy A:352-522 [252012] Other proteins in same PDB: d4fjya1, d4fjya3, d4fjya4 automated match to d1e8wa2 complexed with fjy, so4 | 
|  | Domain d4fjza2: 4fjz A:356-522 [252016] Other proteins in same PDB: d4fjza1, d4fjza3, d4fjza4 automated match to d1e8wa2 complexed with 4fj, so4 | 
|  | Domain d4flha2: 4flh A:352-521 [252034] Other proteins in same PDB: d4flha1, d4flha3, d4flha4 automated match to d1e8wa2 complexed with 14k, so4 | 
|  | Domain d4fula2: 4ful A:357-522 [221536] Other proteins in same PDB: d4fula1, d4fula3, d4fula4 automated match to d1e8ya2 complexed with 0vu | 
|  | Domain d4gb9a2: 4gb9 A:357-522 [252186] Other proteins in same PDB: d4gb9a1, d4gb9a3, d4gb9a4 automated match to d1e8wa2 complexed with 0wr | 
|  | Domain d4hvba2: 4hvb A:357-522 [229090] Other proteins in same PDB: d4hvba1, d4hvba3, d4hvba4 automated match to d1e8ya2 complexed with 19p | 
|  | Domain d4kz0a2: 4kz0 A:357-522 [224530] Other proteins in same PDB: d4kz0a1, d4kz0a3, d4kz0a4 automated match to d1e8ya2 complexed with 1uj, so4 | 
|  | Domain d4ps3a2: 4ps3 A:357-522 [257529] Other proteins in same PDB: d4ps3a1, d4ps3a3, d4ps3a4 automated match to d1e8ya2 complexed with 2wh | 
|  | Domain d4ps7a2: 4ps7 A:357-522 [257535] Other proteins in same PDB: d4ps7a1, d4ps7a3, d4ps7a4 automated match to d1e8ya2 complexed with 2wj | 
|  | Domain d4ps8a2: 4ps8 A:357-522 [257540] Other proteins in same PDB: d4ps8a1, d4ps8a3, d4ps8a4 automated match to d1e8ya2 complexed with 2wk | 
|  | Domain d4wwna2: 4wwn A:352-522 [262147] Other proteins in same PDB: d4wwna1, d4wwna3, d4wwna4 automated match to d1e8wa2 complexed with 3vc, so4 | 
|  | Domain d4wwoa2: 4wwo A:352-522 [262150] Other proteins in same PDB: d4wwoa1, d4wwoa3, d4wwoa4 automated match to d1e8wa2 complexed with 3vd, so4 | 
|  | Domain d4wwpa2: 4wwp A:352-522 [262143] Other proteins in same PDB: d4wwpa1, d4wwpa3, d4wwpa4 automated match to d1e8wa2 complexed with 3ve, gol, so4 | 
Timeline for Species Human (Homo sapiens) [TaxId:9606] from b.7.1.1 Phoshoinositide 3-kinase (PI3K):