Lineage for Protein: alpha-catenin

  1. Root: SCOPe 2.08
  2. Class a: All alpha proteins [46456] (290 folds)
  3. Fold a.24: Four-helical up-and-down bundle [47161] (29 superfamilies)
    core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
  4. Superfamily a.24.9: alpha-catenin/vinculin-like [47220] (2 families) (S)
  5. Family a.24.9.1: alpha-catenin/vinculin [47221] (3 proteins)
    possible duplication: contains several domains of this fold
    The listed PDB entries contain different large fragments but not the whole proteins
  6. Protein alpha-catenin [47222] (2 species)

Species:

  1. Human (Homo sapiens) [TaxId:9606] [63511] (1 PDB entry)
  2. Mouse (Mus musculus) [TaxId:10090] [47223] (3 PDB entries)
    1. Domain for 1dov:
      • Domain d1dova_: 1dov A: [16627]
        N-terminal, dimerization and beta-catenin binding domain
    2. Domain for 1dow:
      • Domain d1dowa_: 1dow A: [16626]
        chimera of the N-terminal domain of alpha-catenin and beta-catenin fragment (chain B)
        has additional subdomain(s) that are not in the common domain
    3. Domains for 1l7c:
      1. Domain d1l7ca1: 1l7c A:388-507 [73647]
        CASP4
      2. Domain d1l7ca2: 1l7c A:508-631 [73648]
        CASP4
      3. Domain d1l7cb1: 1l7c B:391-507 [73649]
        CASP4
      4. Domain d1l7cb2: 1l7c B:508-631 [73650]
        CASP4
      5. Domain d1l7cc1: 1l7c C:393-507 [73651]
        CASP4
      6. Domain d1l7cc2: 1l7c C:508-631 [73652]
        CASP4

More info for Protein alpha-catenin from a.24.9.1: alpha-catenin/vinculin

Timeline for Protein alpha-catenin from a.24.9.1: alpha-catenin/vinculin: