SCOPe 2.08: Family a.24.9.1: alpha-catenin/vinculin

Lineage for Family a.24.9.1: alpha-catenin/vinculin

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.24: Four-helical up-and-down bundle [47161] (29 superfamilies)
   core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down

4. Superfamily a.24.9: alpha-catenin/vinculin-like [47220] (2 families)

5. Family a.24.9.1: alpha-catenin/vinculin [47221] (3 proteins)
   possible duplication: contains several domains of this fold
   The listed PDB entries contain different large fragments but not the whole proteins

Proteins:

1. alpha-catenin [47222] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [63511] (1 PDB entry)

   2. Species Mouse (Mus musculus) [TaxId:10090] [47223] (3 PDB entries)

2. Vinculin [47224] (2 species)

   1. Species Chicken (Gallus gallus) [TaxId:9031] [47225] (3 PDB entries)
      Uniprot P12003

   2. Species Human (Homo sapiens) [TaxId:9606] [101111] (16 PDB entries)
      Uniprot P18206 1-257

3. automated matches [226863] (2 species)
   not a true protein

   1. Species Chicken (Gallus gallus) [TaxId:9031] [225109] (3 PDB entries)

   2. Species Human (Homo sapiens) [TaxId:9606] [224995] (5 PDB entries)

More info for Family a.24.9.1: alpha-catenin/vinculin

Timeline for Family a.24.9.1: alpha-catenin/vinculin:

• Family a.24.9.1: alpha-catenin/vinculin first appeared (with stable ids) in SCOP 1.55
  
• Family a.24.9.1: alpha-catenin/vinculin appears in SCOPe 2.07