Lineage for Species: Human (Homo sapiens), type II [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2943253Fold d.37: CBS-domain pair [54630] (1 superfamily)
    duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a
  4. 2943254Superfamily d.37.1: CBS-domain pair [54631] (2 families) (S)
  5. 2943255Family d.37.1.1: CBS-domain pair [54632] (21 proteins)
    Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain
  6. 2943353Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
  7. 2943359Species Human (Homo sapiens), type II [TaxId:9606] [54634] (3 PDB entries)

PDB entries in Species: Human (Homo sapiens), type II [TaxId: 9606]:

  1. Domain(s) for 1b3o:
    • 2943360Domain d1b3ob4: 1b3o B:112-231 [144354]
      Other proteins in same PDB: d1b3oa1, d1b3ob1
      complexed with cpr, sae, unx
      fragment; missing more than one-third of the common structure and/or sequence
  2. Domain(s) for 1nf7:
    1. 2943361Domain d1nf7a4: 1nf7 A:112-231 [144359]
      Other proteins in same PDB: d1nf7a1, d1nf7b1
      both CBS motifs are partly disordered in both chains, A and B
      complexed with k, myd, rvp, unk
      fragment; missing more than one-third of the common structure and/or sequence
    2. 2943362Domain d1nf7b4: 1nf7 B:112-231 [144360]
      Other proteins in same PDB: d1nf7a1, d1nf7b1
      both CBS motifs are partly disordered in both chains, A and B
      complexed with k, myd, rvp, unk
      fragment; missing more than one-third of the common structure and/or sequence
  3. Domain(s) for 1nfb:
    1. 2943363Domain d1nfba4: 1nfb A:112-231 [144361]
      Other proteins in same PDB: d1nfba1, d1nfbb1
      both CBS motifs are partly disordered in both chains, A and B
      complexed with cpr, nad
      fragment; missing more than one-third of the common structure and/or sequence
    2. 2943364Domain d1nfbb4: 1nfb B:112-231 [144362]
      Other proteins in same PDB: d1nfba1, d1nfbb1
      both CBS motifs are partly disordered in both chains, A and B
      complexed with cpr, nad
      fragment; missing more than one-third of the common structure and/or sequence

More info for Species Human (Homo sapiens), type II [TaxId:9606] from d.37.1.1 Type II inosine monophosphate dehydrogenase CBS domains

Timeline for Species Human (Homo sapiens), type II [TaxId:9606] from d.37.1.1 Type II inosine monophosphate dehydrogenase CBS domains: