Lineage for Protein: Type II inosine monophosphate dehydrogenase CBS domains

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2167405Fold d.37: CBS-domain pair [54630] (1 superfamily)
    duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a
  4. 2167406Superfamily d.37.1: CBS-domain pair [54631] (2 families) (S)
  5. 2167407Family d.37.1.1: CBS-domain pair [54632] (21 protein domains)
    Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain
  6. 2167481Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals

Species:

  1. 2167482Chinese hamster (Cricetulus griseus) [TaxId:10029] [64260] (1 PDB entry)
  2. 2167484Human (Homo sapiens), type I [TaxId:9606] [89899] (1 PDB entry)
  3. 2167487Human (Homo sapiens), type II [TaxId:9606] [54634] (3 PDB entries)
    1. Domain for 1b3o:
    2. Domains for 1nf7:
      1. 2167489Domain d1nf7a4: 1nf7 A:112-231 [144359]
        Other proteins in same PDB: d1nf7a1, d1nf7b1
        both CBS motifs are partly disordered in both chains, A and B
        complexed with k, myd, rvp, unk
      2. 2167490Domain d1nf7b4: 1nf7 B:112-231 [144360]
        Other proteins in same PDB: d1nf7a1, d1nf7b1
        both CBS motifs are partly disordered in both chains, A and B
        complexed with k, myd, rvp, unk
    3. Domains for 1nfb:
      1. 2167491Domain d1nfba4: 1nfb A:112-231 [144361]
        Other proteins in same PDB: d1nfba1, d1nfbb1
        both CBS motifs are partly disordered in both chains, A and B
        complexed with cpr, nad
      2. 2167492Domain d1nfbb4: 1nfb B:112-231 [144362]
        Other proteins in same PDB: d1nfba1, d1nfbb1
        both CBS motifs are partly disordered in both chains, A and B
        complexed with cpr, nad
  4. 2167493Streptococcus pyogenes [TaxId:1314] [54635] (1 PDB entry)

More info for Protein Type II inosine monophosphate dehydrogenase CBS domains from d.37.1.1: CBS-domain pair

Timeline for Protein Type II inosine monophosphate dehydrogenase CBS domains from d.37.1.1: CBS-domain pair: