Lineage for d1nf7b4 (1nf7 B:112-231)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2511352Fold d.37: CBS-domain pair [54630] (1 superfamily)
    duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a
  4. 2511353Superfamily d.37.1: CBS-domain pair [54631] (2 families) (S)
  5. 2511354Family d.37.1.1: CBS-domain pair [54632] (21 proteins)
    Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain
  6. 2511440Protein Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
  7. 2511446Species Human (Homo sapiens), type II [TaxId:9606] [54634] (3 PDB entries)
  8. 2511449Domain d1nf7b4: 1nf7 B:112-231 [144360]
    Other proteins in same PDB: d1nf7a1, d1nf7b1
    both CBS motifs are partly disordered in both chains, A and B
    complexed with k, myd, rvp, unk

Details for d1nf7b4

PDB Entry: 1nf7 (more details), 2.65 Å

PDB Description: Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide
PDB Compounds: (B:) Inosine-5'-monophosphate dehydrogenase 2

SCOPe Domain Sequences for d1nf7b4:

Sequence, based on SEQRES records: (download)

>d1nf7b4 d.37.1.1 (B:112-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type II [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d1nf7b4 d.37.1.1 (B:112-231) Type II inosine monophosphate dehydrogenase CBS domains {Human (Homo sapiens), type II [TaxId: 9606]}

SCOPe Domain Coordinates for d1nf7b4:

Click to download the PDB-style file with coordinates for d1nf7b4.
(The format of our PDB-style files is described here.)

Timeline for d1nf7b4:

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