Lineage for Family d.37.1.1: CBS-domain pair

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2511352Fold d.37: CBS-domain pair [54630] (1 superfamily)
    duplication: tandem repeat of two beta-X-beta-alpha-beta(2)-alpha motifs of similar sequences; 4 layers: a/b/b/a
  4. 2511353Superfamily d.37.1: CBS-domain pair [54631] (2 families) (S)
  5. 2511354Family d.37.1.1: CBS-domain pair [54632] (21 protein domains)
    Pfam PF00571; pairs of CBS domains dimerize to form a stable globular domain, a.k.a. Bateman domain

Protein Domains:

  1. 25113555'-AMP-activated protein kinase subunit gamma-1, AMPKg [160176] (1 species)
  2. 2511383Chloride channel protein 5, ClC-5 [160174] (1 species)
  3. 2511386Chloride channel protein, CBS tandem [143138] (1 species)
    contains additional structures between the two CBS repeats
  4. 2511390Hypothetical protein MTH1622 [102897] (1 species)
  5. 2511393Hypothetical protein Rv2626c [143142] (1 species)
  6. 2511399Hypothetical protein Ta0289 [102899] (1 species)
    contains extra C-terminal zinc-finger domain
  7. 2511405Hypothetical protein TM0892, CBS tandem [143136] (1 species)
  8. 2511409Hypothetical protein TM0935 [102895] (1 species)
  9. 2511412Hypothetical protein VC0737 [143140] (1 species)
    Putative acetoin utilization protein AcuB
  10. 2511416Hypothetical protein YkuL [117881] (1 species)
  11. 2511420Magnesium transporter MgtE [160163] (2 species)
    1. 2511421Species Enterococcus faecalis [TaxId:1351] [160165] (1 PDB entry)
      Uniprot Q830V1 136-262
    2. 2511424Species Thermus thermophilus [TaxId:274] [160164] (2 PDB entries)
      Uniprot Q5SMG8 132-275
  12. 2511431Nuclear protein SNF4 [143134] (1 species)
    duplication: comprises four CBS repeats
  13. 2511440Type II inosine monophosphate dehydrogenase CBS domains [54633] (4 species)
    contains tandem repeat of two CBS domains inserted into the catalytic TIM-barrel domain; may be disordered in the crystals
    1. 2511441Species Chinese hamster (Cricetulus griseus) [TaxId:10029] [64260] (1 PDB entry)
    2. 2511443Species Human (Homo sapiens), type I [TaxId:9606] [89899] (1 PDB entry)
    3. 2511446Species Human (Homo sapiens), type II [TaxId:9606] [54634] (3 PDB entries)
    4. 2511452Species Streptococcus pyogenes [TaxId:1314] [54635] (1 PDB entry)
  14. 2511454Uncharacterized protein C1556.08c [160166] (1 species)
    consists of 4 CBS units
  15. 2511464Uncharacterized protein NE2398 [160172] (1 species)
  16. 2511470Uncharacterized protein PAE2072 [160178] (1 species)
    2 CBS domains = 1 Bateman domain; binds two adenosine nucleotides per subunit (one per one CBS repeat)
  17. 2511478Uncharacterized protein PH0107 [160168] (1 species)
  18. 2511481Uncharacterized protein PH1780 [160159] (1 species)
    duplication: comprises four CBS repeats
  19. 2511485Uncharacterized protein SSO3205 [160170] (1 species)
    duplication: comprises four CBS repeats
  20. 2511489Uncharacterized protein ST2348 [160161] (1 species)
  21. 2511492automated matches [190627] (7 species)
    not a true protein
    1. 2511493Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [231218] (4 PDB entries)
    2. 2511510Species Geobacillus kaustophilus [TaxId:235909] [188209] (1 PDB entry)
    3. 2511513Species Human (Homo sapiens) [TaxId:9606] [187902] (3 PDB entries)
    4. 2511529Species Pyrococcus horikoshii [TaxId:53953] [188263] (1 PDB entry)
    5. 2511531Species Sulfolobus tokodaii [TaxId:273063] [187663] (1 PDB entry)
    6. 2511533Species Thermus thermophilus HB8 [TaxId:300852] [231686] (1 PDB entry)
    7. 2511535Species Thermus thermophilus [TaxId:300852] [338063] (1 PDB entry)

More info for Family d.37.1.1: CBS-domain pair

Timeline for Family d.37.1.1: CBS-domain pair: