SCOPe 2.08: Protein: DNA excision repair protein ERCC-1

Lineage for Protein: DNA excision repair protein ERCC-1

Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds)
Fold a.60: SAM domain-like [47768] (17 superfamilies)
4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
Superfamily a.60.2: RuvA domain 2-like [47781] (7 families)
duplication: contains two helix-hairpin-helix (HhH) motifs

Family a.60.2.5: Hef domain-like [140629] (4 proteins)
helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain ((81795), that contains a single NMR structure of a monomeric truncated domain, 1kft)

Protein DNA excision repair protein ERCC-1 [140630] (1 species)

Species:

Human (Homo sapiens) [TaxId:9606] [140631] (3 PDB entries)
Uniprot P07992 219-296! Uniprot P07992 220-297
1. Domain for 1z00:
  - Domain d1z00a1: 1z00 A:220-297 [124294]
    Other proteins in same PDB: d1z00a2, d1z00b1
2. Domain for 2a1j:
  - Domain d2a1jb1: 2a1j B:220-296 [126001]
    Other proteins in same PDB: d2a1ja1, d2a1jb2
    protein/DNA complex; complexed with hg
3. Domain for 2mut:
  - Domain d2muta1: 2mut A:220-297 [274219]
    Other proteins in same PDB: d2muta2, d2muta3, d2mutb1, d2mutb2
    automated match to d1z00a1
    mutant

More info for Protein DNA excision repair protein ERCC-1 from a.60.2.5: Hef domain-like

Timeline for Protein DNA excision repair protein ERCC-1 from a.60.2.5: Hef domain-like:

Protein DNA excision repair protein ERCC-1 from a.60.2.5: Hef domain-like first appeared in SCOP 1.73
Protein DNA excision repair protein ERCC-1 from a.60.2.5: Hef domain-like appears in SCOPe 2.07