Lineage for Fold a.60: SAM domain-like

  1. Root: SCOPe 2.08
  2. Class a: All alpha proteins [46456] (290 folds)
  3. Fold a.60: SAM domain-like [47768] (17 superfamilies)
    4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

Superfamilies:

  1. a.60.1: SAM/Pointed domain [47769] (4 families) (S)
  2. a.60.2: RuvA domain 2-like [47781] (7 families) (S)
    duplication: contains two helix-hairpin-helix (HhH) motifs
  3. a.60.3: C-terminal domain of RNA polymerase alpha subunit [47789] (1 family) (S)
    contains one classic and one pseudo HhH motifs
  4. a.60.4: Rad51 N-terminal domain-like [47794] (4 families) (S)
    contains one classic and one pseudo HhH motifs
  5. a.60.5: Barrier-to-autointegration factor, BAF [47798] (1 family) (S)
    contains one classic and one pseudo HhH motifs
    automatically mapped to Pfam PF02961
  6. a.60.6: DNA polymerase beta, N-terminal domain-like [47802] (2 families) (S)
    contains one classic and one pseudo HhH motifs
  7. a.60.7: 5' to 3' exonuclease, C-terminal subdomain [47807] (2 families) (S)
  8. a.60.8: HRDC-like [47819] (5 families) (S)
  9. a.60.9: lambda integrase-like, N-terminal domain [47823] (2 families) (S)
  10. a.60.10: Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain [47831] (1 family) (S)
  11. a.60.11: Hypothetical protein YjbJ [69047] (2 families) (S)
    automatically mapped to Pfam PF05532
  12. a.60.12: PsbU/PolX domain-like [81585] (3 families) (S)
    contains one classic and one pseudo HhH motifs
  13. a.60.13: Putative methyltransferase TM0872, insert domain [81799] (1 family) (S)
  14. a.60.14: eIF2alpha middle domain-like [116742] (2 families) (S)
  15. a.60.15: YozE-like [140652] (1 family) (S)
  16. a.60.16: GspK insert domain-like [158544] (1 family) (S)
    tandem repeat of two SAM-like domains iserted into pilin fold; domain 1 contains one classic HhH motif
  17. a.60.17: SAM domain from DprA-like [418757] (1 family) (S)

More info for Fold a.60: SAM domain-like

Timeline for Fold a.60: SAM domain-like: