Lineage for d2a1ja1 (2a1j A:837-898)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2715427Fold a.60: SAM domain-like [47768] (17 superfamilies)
    4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
  4. 2715662Superfamily a.60.2: RuvA domain 2-like [47781] (7 families) (S)
    duplication: contains two helix-hairpin-helix (HhH) motifs
  5. 2715718Family a.60.2.5: Hef domain-like [140629] (4 proteins)
    helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain ((81795), that contains a single NMR structure of a monomeric truncated domain, 1kft)
  6. 2715728Protein DNA repair endonuclease XPF [140634] (2 species)
  7. 2715736Species Human (Homo sapiens) [TaxId:9606] [140636] (4 PDB entries)
    Uniprot Q92889 823-905! Uniprot Q92889 837-898
  8. 2715737Domain d2a1ja1: 2a1j A:837-898 [126000]
    Other proteins in same PDB: d2a1jb1, d2a1jb2
    protein/DNA complex; complexed with hg

Details for d2a1ja1

PDB Entry: 2a1j (more details), 2.7 Å

PDB Description: Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1
PDB Compounds: (A:) DNA repair endonuclease XPF

SCOPe Domain Sequences for d2a1ja1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2a1ja1 a.60.2.5 (A:837-898) DNA repair endonuclease XPF {Human (Homo sapiens) [TaxId: 9606]}
pqdfllkmpgvnakncrslmhhvkniaelaalsqdeltsilgnaanakqlydfihtsfae
vv

SCOPe Domain Coordinates for d2a1ja1:

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Timeline for d2a1ja1: