SCOPe 2.08: Species: Human (Homo sapiens) [TaxId: 9606]

Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds)
Fold a.60: SAM domain-like [47768] (17 superfamilies)
4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
Superfamily a.60.2: RuvA domain 2-like [47781] (7 families)
duplication: contains two helix-hairpin-helix (HhH) motifs

Family a.60.2.5: Hef domain-like [140629] (4 proteins)
helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain ((81795), that contains a single NMR structure of a monomeric truncated domain, 1kft)

Protein DNA repair endonuclease XPF [140634] (2 species)
Species Human (Homo sapiens) [TaxId:9606] [140636] (4 PDB entries)
Uniprot Q92889 823-905! Uniprot Q92889 837-898

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

Domain(s) for 1z00:
- Domain d1z00b1: 1z00 B:823-905 [124295]
  Other proteins in same PDB: d1z00a1, d1z00a2
Domain(s) for 2a1j:
- Domain d2a1ja1: 2a1j A:837-898 [126000]
  Other proteins in same PDB: d2a1jb1, d2a1jb2
  protein/DNA complex; complexed with hg
Domain(s) for 2aq0:
1. Domain d2aq0a_: 2aq0 A: [127136]
  automated match to d2aq0a1
2. Domain d2aq0b_: 2aq0 B: [127137]
  automated match to d2aq0a1
Domain(s) for 2mut:
- Domain d2mutb1: 2mut B:823-905 [274222]
  Other proteins in same PDB: d2muta1, d2muta2, d2muta3, d2mutb2
  automated match to d2aq0a_
  mutant

More info for Species Human (Homo sapiens) [TaxId:9606] from a.60.2.5 DNA repair endonuclease XPF

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.60.2.5 DNA repair endonuclease XPF:

Species Human (Homo sapiens) [TaxId:9606] from a.60.2.5 DNA repair endonuclease XPF first appeared in SCOP 1.73
Species Human (Homo sapiens) [TaxId:9606] from a.60.2.5 DNA repair endonuclease XPF appears in SCOPe 2.07