PDB entry 2a1j

View 2a1j on RCSB PDB site
Description: Crystal Structure of the Complex between the C-Terminal Domains of Human XPF and ERCC1
Class: DNA binding protein
Keywords: XPF, ERCC1, Xeroderma pigmentosum, NER, DNA repair, endonuclease, helix-hairpin-helix, DNA BINDING PROTEIN
Deposited on 2005-06-20, released 2005-08-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.241
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA repair endonuclease XPF
    Species: Homo sapiens [TaxId:9606]
    Gene: ERCC4, ERCC11, XPF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2a1ja1
  • Chain 'B':
    Compound: DNA excision repair protein ERCC-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ERCC1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07992 (14-90)
      • cloning artifact (12-13)
    Domains in SCOPe 2.08: d2a1jb1, d2a1jb2
  • Heterogens: HG

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2a1jA (A:)
mpqdfllkmpgvnakncrslmhhvkniaelaalsqdeltsilgnaanakqlydfihtsfa
evv

    Sequence, based on observed residues (ATOM records): (download) 
    >2a1jA (A:)
pqdfllkmpgvnakncrslmhhvkniaelaalsqdeltsilgnaanakqlydfihtsfae
vv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2a1jB (B:)
mgsshhhhhhsqdpadllmekleqdfvsrvteclttvksvnktdsqtllttfgsleqlia
asredlalcpglgpqkarrlfdvlhepflkv

    Sequence, based on observed residues (ATOM records): (download) 
    >2a1jB (B:)
dpadllmekleqdfvsrvteclttvksvnktdsqtllttfgsleqliaasredlalcpgl
gpqkarrlfdvlhepflkv